PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35571728-7	2022	Molecular docking results revealed that beta-carotene and sitosterol were acting as interference factors in attenuating inflammation by binding to an accessory protein of ERK, JNK, AKT, and NF-kappaB p65.	beta Carotene	40-53	mitogen-activated protein kinase 8	Mus musculus	176-179	
35402622-14	2022	Subsequently, we observed that adding 1*10-6 mol/L quercetin, 1*10-5  mol/L kaempferol, and 1*10-5  mol/L beta-carotene activated the ERK/JNK cascades and the heterodimer complex AP-1(Fos/Jun) in the MAPK pathway.	beta Carotene	106-119	mitogen-activated protein kinase 8	Mus musculus	138-141	
30460722-0	2019	beta-carotene attenuates lipopolysaccharide-induced inflammation via inhibition of the NF-kappaB, JAK2/STAT3 and JNK/p38 MAPK signaling pathways in macrophages.	beta Carotene	0-13	mitogen-activated protein kinase 8	Mus musculus	113-116	
30460722-6	2019	LPS-induced JAK2/STAT3, IkappaB/NF-kappaB p65, JNK/p38 MAPK signal activation were significantly attenuated (p < 0.05) by beta-carotene in a dose-dependent manner.	beta Carotene	125-138	mitogen-activated protein kinase 8	Mus musculus	47-50	
30460722-7	2019	In conclusion, beta-carotene could attenuate LPS-induced inflammation via inhibition of the NF-kappaB, JAK2/STAT3, and JNK/p38 MAPK signaling pathways in macrophages.	beta Carotene	15-28	mitogen-activated protein kinase 8	Mus musculus	119-122	
24668641-8	2014	The c-Jun N-terminal kinase (JNK) inhibitor, SP600125, suppressed the beta-carotene-induced GSH increase, whereas a p38 mitogen-activated protein kinase inhibitor or an extracellular signal-regulated kinase 1/2 inhibitor did not.	beta Carotene	70-83	mitogen-activated protein kinase 8	Mus musculus	29-32	
24668641-9	2014	The JNK inhibitor also suppressed the beta-carotene-induced GCL protein expression, and consistently beta-carotene induced JNK phosphorylation.	beta Carotene	38-51	mitogen-activated protein kinase 8	Mus musculus	4-7	
24668641-9	2014	The JNK inhibitor also suppressed the beta-carotene-induced GCL protein expression, and consistently beta-carotene induced JNK phosphorylation.	beta Carotene	101-114	mitogen-activated protein kinase 8	Mus musculus	4-7	
24668641-9	2014	The JNK inhibitor also suppressed the beta-carotene-induced GCL protein expression, and consistently beta-carotene induced JNK phosphorylation.	beta Carotene	101-114	mitogen-activated protein kinase 8	Mus musculus	123-126	
23442671-7	2012	beta-Carotene also suppressed (p<0.05) NF-kappaB (p50 and p65), phosphorylation of extracellular-signal-related kinase (ERK), p38, and c-Jun N-terminal kinase (JNK) expression.	beta Carotene	0-13	mitogen-activated protein kinase 8	Mus musculus	138-161	
23442671-7	2012	beta-Carotene also suppressed (p<0.05) NF-kappaB (p50 and p65), phosphorylation of extracellular-signal-related kinase (ERK), p38, and c-Jun N-terminal kinase (JNK) expression.	beta Carotene	0-13	mitogen-activated protein kinase 8	Mus musculus	163-166