PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7681466-8 1993 Compared with a control group (n = 4), hIGF-I significantly stimulated hexose uptake into heart, soleus and red quadriceps muscles and hIGFBP-1 partially reversed this effect. Hexoses 71-77 insulin like growth factor 1 Homo sapiens 39-45 2164929-5 1990 In contrast, IGF-1 stimulates hexose uptake in the patient"s fibroblasts 1.8 times, a similar value to that obtained by stimulation of control fibroblasts with insulin or IGF-1. Hexoses 30-36 insulin like growth factor 1 Homo sapiens 13-18 2164929-9 1990 As an insulin concentration of 10 microM is unable to give maximal stimulation of glucose uptake in the patient"s fibroblasts, which is already seen with 10 nM IGF-1, it seems that occupation of IGF-1 receptors by insulin on the patient"s cells is less efficient at stimulating hexose uptake compared to homologous activation. Hexoses 278-284 insulin like growth factor 1 Homo sapiens 195-200 2649887-5 1989 Microinjection of a monoclonal antibody directed against the tyrosine kinase domain of the human insulin receptor blocks activation of hexose uptake by insulin-like growth factor I and insulin but has no effect on basal uptake. Hexoses 135-141 insulin like growth factor 1 Homo sapiens 152-180 7514206-8 1994 IGFBP-1 also appears to inhibit IGF-I hexose-stimulated uptake. Hexoses 38-44 insulin like growth factor 1 Homo sapiens 32-37