PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27641460-3 2016 Interestingly, this turn motif displays strong similarities with the FKBP52 FK1 domain-binding moiety of macrolide immunomodulators such as rapamycin and GPI-1046, an immunophilin ligand with neuroprotective characteristics. Macrolides 105-114 FKBP prolyl isomerase 4 Homo sapiens 69-75 7681058-2 1993 The ability of hsp56 to bind the immunosuppressive macrolide FK506 has led to the speculation that the steroid receptor and immunophilin signal transduction pathways are functionally interrelated. Macrolides 51-60 FKBP prolyl isomerase 4 Homo sapiens 15-20 8955134-11 1996 These results suggest that FAP48 shares or overlaps the macrolide binding site on FKBP59 as well as on FKBP12 and therefore may represent a natural common ligand of these immunosuppressant drug receptors. Macrolides 56-65 FKBP prolyl isomerase 4 Homo sapiens 82-88