PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34774865-9	2021	Considering the increased level of MG in diabetic condition, the current study appears physiologically relevant in terms of understanding AGE-mediated protein modification and subsequent structural changes.	Pyruvaldehyde	35-37	renin binding protein	Homo sapiens	138-141	
16037241-3	2005	As reactive intermediates of AGE formation, neurotoxic reactive dicarbonyl compounds such as glyoxal and methylglyoxal have been identified.	Pyruvaldehyde	105-118	renin binding protein	Homo sapiens	29-32	
34142632-2	2022	Glyoxal (GO) and methylglyoxal (MGO) are reactive intermediates created by food processing and they are precursors of advanced glycation end products (AGE) that cause glycative stress.	Pyruvaldehyde	17-30	renin binding protein	Homo sapiens	151-154	
34142632-2	2022	Glyoxal (GO) and methylglyoxal (MGO) are reactive intermediates created by food processing and they are precursors of advanced glycation end products (AGE) that cause glycative stress.	Pyruvaldehyde	32-35	renin binding protein	Homo sapiens	151-154	
35625570-11	2022	Tannerella forsythia, a common gram-negative anaerobe periodontal pathogen in the oral biofilm, was observed to produce methylglyoxal (precursor of AGE) in the gingival tissues.	Pyruvaldehyde	129-142	renin binding protein	Homo sapiens	157-160	
33359687-4	2021	Here, we comprehensively investigate age-related accumulation of AGEs and dicarbonyls, including methylglyoxal (MG), glyoxal (GO), and 3-deoxyglucosone (3-DG), and the effects of mitochondrial reactive oxygen species (ROS) on cerebral AGEs accumulation, mitochondrial function, and oxidative stress in the aging human and mouse brain.	Pyruvaldehyde	97-110	renin binding protein	Homo sapiens	37-40	
33359687-4	2021	Here, we comprehensively investigate age-related accumulation of AGEs and dicarbonyls, including methylglyoxal (MG), glyoxal (GO), and 3-deoxyglucosone (3-DG), and the effects of mitochondrial reactive oxygen species (ROS) on cerebral AGEs accumulation, mitochondrial function, and oxidative stress in the aging human and mouse brain.	Pyruvaldehyde	112-114	renin binding protein	Homo sapiens	37-40	
33223150-4	2021	In this study, immunoextraction based on polyclonal anti-HSA antibodies was used with high-performance affinity microcolumns to see how AGE-related modifications produced by glyoxal (Go) and methylglyoxal (MGo) affected the binding of HSA to several first- and second-generation sulfonylureas, a class of drugs used to treat type II diabetes and known to bind to HSA.	Pyruvaldehyde	191-204	renin binding protein	Homo sapiens	136-139	
33223150-4	2021	In this study, immunoextraction based on polyclonal anti-HSA antibodies was used with high-performance affinity microcolumns to see how AGE-related modifications produced by glyoxal (Go) and methylglyoxal (MGo) affected the binding of HSA to several first- and second-generation sulfonylureas, a class of drugs used to treat type II diabetes and known to bind to HSA.	Pyruvaldehyde	206-209	renin binding protein	Homo sapiens	136-139