PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19926874-6 2010 In contrast, secondary necrotic VSMCs release both IL-1alpha and caspase-activated IL-1beta, augmenting IL-6 and MCP-1 production. vsmcs 32-37 interleukin 6 Homo sapiens 104-108 18195163-13 2008 Our data suggest that fetally derived trophoblasts require direct cell-cell contact with maternally derived VSMCs to downregulate VSMC C3 and interleukin-6 expression and to avoid atherosis. vsmcs 108-113 interleukin 6 Homo sapiens 142-155 11076827-7 2000 5-HT induced IL-6 production by VSMCs in a time- and dose-dependent manner, with increased IL-6 mRNA accumulation and nuclear factor-kappaB activation. vsmcs 32-37 interleukin 6 Homo sapiens 13-17 14754879-7 2004 Conversely, TGF-beta1 inhibition of cytokine-mediated induction of iNOS and IL-6 expression was completely blocked in Smad3-deficient VSMCs. vsmcs 134-139 interleukin 6 Homo sapiens 76-80 11799073-6 2002 One of signaling pathways by which GSA activates VSMCs appears to be via nuclear factor kappaB activation, leading to induction of MCP-1 and IL-6 gene expression, comparable to the effects of lipopolysaccharide, TNF-alphaa, and IL-1alphab. vsmcs 49-54 interleukin 6 Homo sapiens 141-145 11799073-9 2002 Incubation of VSMCs with the antioxidant N-acetylcysteine suppressed GSA-elicited mRNA induction of MCP-1 and IL-6. vsmcs 14-19 interleukin 6 Homo sapiens 110-114 24222216-6 2013 The optical densities in MTT assay of the activated, inactivated, and control groups was 1.35 +- 0.11, 1.01 +- 0.09, and 0.29 +- 0.01, respectively, which correlated positively with the initial IL-6 level in the supernatant of the VSMCs (r = 0.63, P < 0.05). vsmcs 231-236 interleukin 6 Homo sapiens 194-198 31159449-5 2019 Our previous studies demonstrated that increased interleukin (IL)-6, epidermal growth factor family ligands, and erbB2 receptor, some of which amplify inflammation and, consequently, induce CID, were induced by IH and were involved in the proliferation of VSMCs. vsmcs 256-261 interleukin 6 Homo sapiens 49-67 29228352-6 2018 Exposure of VSMCs to uraemic serum or recombinant TNF-alpha lead to a strong upregulation of IL-6 mRNA expression and protein secretion, which was mediated by activator protein 1 (AP-1)/c-FOS-pathway signalling. vsmcs 12-17 interleukin 6 Homo sapiens 93-97