PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10641290-1 1999 Part I: Immobilization, characterization and stabilization of acetylcholinesterase and organophosphate hydrolase on silica supports. Silicon Dioxide 116-122 acetylcholinesterase (Cartwright blood group) Homo sapiens 62-82 15522601-0 2004 Development of acetylcholinesterase silica sol-gel immobilized biosensor--an application towards oxydemeton methyl detection. Silicon Dioxide 36-42 acetylcholinesterase (Cartwright blood group) Homo sapiens 15-35 15522601-1 2004 An amperometric silica sol-gel film immobilized biosensor doped with acetylcholinesterase was fabricated in the laboratory finding application in organophosphate detection based on enzyme inhibition. Silicon Dioxide 16-22 acetylcholinesterase (Cartwright blood group) Homo sapiens 69-89 10641290-7 1999 Two different covalent chemistries were used to immobilize AChE and OPH to these porous and non-porous silica beads. Silicon Dioxide 103-109 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-63 29451128-6 2018 The entrapped AChE hydrolyzed paraoxon to produce p-nitrophenol within the hydrogel microstructure, which subsequently quenched the fluorescence of the QDs on the surface of Ag@Silica. Silicon Dioxide 177-183 acetylcholinesterase (Cartwright blood group) Homo sapiens 14-18 31252259-1 2019 A stable and sensitive electrochemical acetylcholinesterase (AChE) biosensor for detection of organophosphorus pesticides (OPs) was developed by doping Au nanorods (AuNRs)@mesoporous SiO2 (MS) core-shell nanoparticles into CS/TiO2-CS (CS denotes for chitosan) immobilization matrix. Silicon Dioxide 183-187 acetylcholinesterase (Cartwright blood group) Homo sapiens 39-59 31252259-1 2019 A stable and sensitive electrochemical acetylcholinesterase (AChE) biosensor for detection of organophosphorus pesticides (OPs) was developed by doping Au nanorods (AuNRs)@mesoporous SiO2 (MS) core-shell nanoparticles into CS/TiO2-CS (CS denotes for chitosan) immobilization matrix. Silicon Dioxide 183-187 acetylcholinesterase (Cartwright blood group) Homo sapiens 61-65 31249381-3 2019 In this work, we select four enzymes (urease, acetylcholinesterase, glucose oxidase, and aldolase) to be attached on silica microcapsules and study how their turnover number and conformational dynamics affect the self-propulsion, combining both an experimental and molecular dynamics simulations approach. Silicon Dioxide 117-123 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-66 35491047-0 2022 Acetylcholinesterase-capped mesoporous silica gated switches for selective detection of high-toxicity organophosphate compounds. Silicon Dioxide 39-45 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 30672607-0 2019 Acetylcholinesterase with mesoporous silica: Covalent immobilization, physiochemical characterization, and its application in food for pesticide detection. Silicon Dioxide 37-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 30672607-2 2019 This study reports on Santa Barbara Amorphous (SBA-15), a type of mesoporous silica nanoparticles, for efficient and stable acetylcholinesterase (AChE) adhesion toward detection of toxic pesticides. Silicon Dioxide 77-83 acetylcholinesterase (Cartwright blood group) Homo sapiens 124-144 30672607-2 2019 This study reports on Santa Barbara Amorphous (SBA-15), a type of mesoporous silica nanoparticles, for efficient and stable acetylcholinesterase (AChE) adhesion toward detection of toxic pesticides. Silicon Dioxide 77-83 acetylcholinesterase (Cartwright blood group) Homo sapiens 146-150 31041959-1 2019 Mesoporous silica nanoparticles capped with acetylcholinesterase, through boronic ester linkages, selectively release an entrapped cargo in the presence of acetylcholine. Silicon Dioxide 11-17 acetylcholinesterase (Cartwright blood group) Homo sapiens 44-64 28169488-0 2017 Acetylcholinesterase-capped Mesoporous Silica Nanoparticles Controlled by the Presence of Inhibitors. Silicon Dioxide 39-45 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 28169488-1 2017 Two different acetylcholinesterase (AChE)-capped mesoporous silica nanoparticles (MSNs), S1-AChE and S2-AChE, were prepared and characterized. Silicon Dioxide 60-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 14-34 28169488-1 2017 Two different acetylcholinesterase (AChE)-capped mesoporous silica nanoparticles (MSNs), S1-AChE and S2-AChE, were prepared and characterized. Silicon Dioxide 60-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 36-40 27754682-0 2016 Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant). Silicon Dioxide 39-45 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 28220973-2 2017 We prepared and characterized Janus Au-mesoporous silica nanoparticles functionalized with acetylcholinesterase on the Au face and with supramolecular beta-cyclodextrin:benzimidazole inclusion complexes as caps on the mesoporous silica face. Silicon Dioxide 50-56 acetylcholinesterase (Cartwright blood group) Homo sapiens 91-111 27754682-1 2016 Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP). Silicon Dioxide 11-17 acetylcholinesterase (Cartwright blood group) Homo sapiens 72-92 26516688-7 2016 Results confirm that reliable fluorescent monitoring AChE-catalyzed hydrolysis of ACh is possible through the H-function properties of Tb(III)-doped silica nanoparticles. Silicon Dioxide 149-155 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-57 24321276-3 2014 Herein is presented the results of selective screening assays of a coumarin derivatives library using BChE and AChE covalently immobilized onto silica fused capillaries (ICERs, 15 cm x 0.1 mm ID). Silicon Dioxide 144-150 acetylcholinesterase (Cartwright blood group) Homo sapiens 111-115 25365355-0 2016 Acetylcholinesterase immobilized onto PEI-coated silica nanoparticles. Silicon Dioxide 49-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 26513558-1 2016 A new mesoporous silica protected plasmonic photocatalyst, Au/BiOCl@mSiO2, was prepared by a modified AcHE method and a subsequent UV light induced photodeposition process. Silicon Dioxide 17-23 acetylcholinesterase (Cartwright blood group) Homo sapiens 102-106 25365355-9 2016 The storage stability of acetylcholinesterase was increased when immobilized onto the novel PEI-coated silica nanoparticles. Silicon Dioxide 103-109 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-45 22814970-9 2013 Combined use of atomic-force microscopy and CLSM revealed that AChE was homogeneously and selectively distributed on the SiO(2) microstructures at a suitable distance from the reflective surface. Silicon Dioxide 121-127 acetylcholinesterase (Cartwright blood group) Homo sapiens 63-67 25050480-1 2014 An acetylcholinesterase-immobilized sensor unit was successfully prepared by encapsulating the enzyme within hybrid mesoporous silica membranes (F127-MST). Silicon Dioxide 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 3-23 25924313-6 2014 The biosensor is based on a self-assembled platform formed by poly(allylamine) hydrochloride (PAH) and silicon dioxide nanoparticles (SiO2-Np) that contains the immobilized enzyme AChE. Silicon Dioxide 103-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 180-184 24770670-2 2014 Acetylcholinesterase (AChE) was further encapsulated in a silica matrix and immobilized on the Au-PPy-rGO nanocomposite by co-deposition with (NH4)2SiF6. Silicon Dioxide 58-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 24770670-2 2014 Acetylcholinesterase (AChE) was further encapsulated in a silica matrix and immobilized on the Au-PPy-rGO nanocomposite by co-deposition with (NH4)2SiF6. Silicon Dioxide 58-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 22-26 24770670-5 2014 Since AChE molecules were protected by the circumambient silica matrix, which provided a biocompatible environment and facilitated mass transport, the fabricated AChE biosensor displayed high stability and excellent activity together with a fast response to organophosphorus pesticides. Silicon Dioxide 57-63 acetylcholinesterase (Cartwright blood group) Homo sapiens 6-10 24770670-5 2014 Since AChE molecules were protected by the circumambient silica matrix, which provided a biocompatible environment and facilitated mass transport, the fabricated AChE biosensor displayed high stability and excellent activity together with a fast response to organophosphorus pesticides. Silicon Dioxide 57-63 acetylcholinesterase (Cartwright blood group) Homo sapiens 162-166 21591743-3 2011 This is the first report of AChE encapsulated in monolithic silica for use as an immobilized enzyme reactor (IMER), and the first use of such IMERs for mixture screening. Silicon Dioxide 60-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 28-32 22430667-6 2012 The reaction kinetic parameters for AChE were successfully estimated with the silica particles and 2. Silicon Dioxide 78-84 acetylcholinesterase (Cartwright blood group) Homo sapiens 36-40 22430667-7 2012 These results reveal that the ensemble of the silica particles and 2 can be utilized for AChE assay. Silicon Dioxide 46-52 acetylcholinesterase (Cartwright blood group) Homo sapiens 89-93 22430667-8 2012 Moreover, the fluorescence spectra of the ensemble of the silica particles and 2 containing AChE were also measured after further addition of either neostigmine or tacrine which are typical inhibitors of AChE. Silicon Dioxide 58-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 204-208 22430667-9 2012 The results manifest that the ensemble of the emissive silica particles and 2 is also useful for screening the inhibitors of AChE. Silicon Dioxide 55-61 acetylcholinesterase (Cartwright blood group) Homo sapiens 125-129 21880553-2 2012 An acetylcholinesterase (AChE) based amperometric biosensor was developed by silica sol-gel film immobilization of the enzyme onto the carbon paste electrode. Silicon Dioxide 77-83 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-29 20593080-1 2010 A bioactive paper-based colorimetric "dipstick" bioassay is reported that is based on acetylcholinesterase (AChE) catalyzed enlargement of gold nanoparticles that are co-entrapped with the enzyme in a sol-gel based silica material that is coated on a functionalized paper substrate. Silicon Dioxide 215-221 acetylcholinesterase (Cartwright blood group) Homo sapiens 86-106 20949898-1 2010 A fluorimetric acetylcholinesterase (AChE) assay was developed and characterized both in solution and with the enzyme entrapped in sol-gel-derived silica. Silicon Dioxide 147-153 acetylcholinesterase (Cartwright blood group) Homo sapiens 37-41 20949898-4 2010 The assay was extended to the fabrication of functional AChE microarrays using contact pin-printing of sol-gel-derived silica. Silicon Dioxide 119-125 acetylcholinesterase (Cartwright blood group) Homo sapiens 56-60 20593080-1 2010 A bioactive paper-based colorimetric "dipstick" bioassay is reported that is based on acetylcholinesterase (AChE) catalyzed enlargement of gold nanoparticles that are co-entrapped with the enzyme in a sol-gel based silica material that is coated on a functionalized paper substrate. Silicon Dioxide 215-221 acetylcholinesterase (Cartwright blood group) Homo sapiens 108-112 19899797-2 2010 As a model system, immobilization of acetylcholinesterase (AChE) was investigated using biomagnetic glasses composed of a magnetic core with a size tunable porous silica shell. Silicon Dioxide 163-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 37-57 19899797-2 2010 As a model system, immobilization of acetylcholinesterase (AChE) was investigated using biomagnetic glasses composed of a magnetic core with a size tunable porous silica shell. Silicon Dioxide 163-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-63 17499494-1 2007 A simple method to immobilize acetylcholinesterase (AChE) on silica sol-gel (SiSG) film assembling gold nanoparticles (AuNPs) was proposed, thus a sensitive, fast and stable amperometric sensor for quantitative determination of organophosphorous insecticide was developed. Silicon Dioxide 61-67 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-50 18082383-7 2008 They might be explained by the interaction of either AChE or test compounds with the silica of the TLC plates, resulting in an altered affinity of the enzyme for the compounds. Silicon Dioxide 85-91 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-57 17499494-1 2007 A simple method to immobilize acetylcholinesterase (AChE) on silica sol-gel (SiSG) film assembling gold nanoparticles (AuNPs) was proposed, thus a sensitive, fast and stable amperometric sensor for quantitative determination of organophosphorous insecticide was developed. Silicon Dioxide 61-67 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-56