PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29691156-1	2018	Five lactam chemotypes amenable by the Castagnoli-Cushman reaction of imines and cyclic anhydrides have been investigated for their ability to activate p53 tumor suppressing transcription factor thus induce apoptosis in p53+ cancer cells.	Imines	70-76	tumor protein p53	Homo sapiens	152-155	
30057300-5	2018	Further experimental testing demonstrated that Michael acceptors, aldehydes, imines, and primary alcohols can promote thermodynamic stabilization of mutant p53.	Imines	77-83	tumor protein p53	Homo sapiens	156-159	
30057300-6	2018	Moreover, mild thiol reactivity, often coupled with combined chemical functional groups, such as in imines, aldehydes, and primary alcohols, can stimulate mutant p53 refolding.	Imines	100-106	tumor protein p53	Homo sapiens	162-165