PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6697533-1	1984	Gidez et al described a double precipitation method with polyanions to separate high density lipoprotein (HDL) subfractions, using sodium heparin to precipitate very low density lipoprotein (VLDL) and low density lipoprotein (LDL) first, and dextran sulphate 15000 to precipitate HDL2 from total HDL afterwards.	Heparin	131-145	junctophilin 3	Homo sapiens	280-284	
7175378-5	1982	HDL2 cholesterol is calculated as the difference between total HDL cholesterol (heparin-Mn2+ supernatant) and HDL3 cholesterol (dextran sulfate supernatant).	Heparin	80-87	junctophilin 3	Homo sapiens	0-4	
7123544-3	1982	The result, in conjunction with the HDL-cholesterol concentration simultaneously determined by the heparin-Ca2+ method, enabled us to calculate the HDL2- and HDL3-cholesterol concentrations.	Heparin	99-106	junctophilin 3	Homo sapiens	148-152	
7046999-1	1982	Recent evidence has suggested that the major physiological substrate of the heparin-releasable (postheparin plasma) hepatic lipase is HDL2-phospholipid.	Heparin	76-83	junctophilin 3	Homo sapiens	134-138	
7418200-5	1980	Heparin affinity chromatography of HDL2 in the presence of Ca2+ and Mn2+ showed an interaction of apolipoprotein E-containing HDL2 subfraction only in conditions involving Mn2+.	Heparin	0-7	junctophilin 3	Homo sapiens	35-39	
7285347-5	1981	The method provides an alternative to the recently described heparin/MnCl2/dextran sulphate double-precipitation procedure, with the advantage of permitting quantitative recovery of intact HDL2.	Heparin	61-68	junctophilin 3	Homo sapiens	189-193	
7314590-4	1981	Administration of heparin into the patients was responsible for an increase in the level of unsaturated phospholipids in HDL2 fraction (while they decreased in VLDL/as well as for a decrease in the ratio cholesterol/phospholipids.	Heparin	18-25	junctophilin 3	Homo sapiens	121-125	
7418200-5	1980	Heparin affinity chromatography of HDL2 in the presence of Ca2+ and Mn2+ showed an interaction of apolipoprotein E-containing HDL2 subfraction only in conditions involving Mn2+.	Heparin	0-7	junctophilin 3	Homo sapiens	126-130	
7822240-5	1994	Apolipoprotein (apo) E-free HDL2 from the patients, separated by heparin-Sepharose column chromatography, was rich in CE, poor in triglycerides (TG), and enlarged in size on 4-30% nondenaturing polyacrylamide gradient gel electrophoresis.	Heparin	65-72	junctophilin 3	Homo sapiens	28-32	
7897316-8	1994	HDL density profiles of the study groups prior to the administration of heparin demonstrated two distinct peaks at density 1.09 g/ml (HDL2) and 1.13 g/ml (HDL3).	Heparin	72-79	junctophilin 3	Homo sapiens	134-138	
7897316-9	1994	However, after the administration of heparin to the HTG group, only a single peak in the HDL profile was evident that was located at the density region corresponding to HDL2 (1.09 g/ml).	Heparin	37-44	junctophilin 3	Homo sapiens	169-173	
1364970-5	1992	The in vivo acceleration of lipoprotein metabolism by heparin resulted in: 1) the reduction of VLDL-TAG and HDL2-TAG, and in the increase of HDL3-TAG, 2) the appearance of positive relation of HDL2-C to the LPL activity and of opposite relation to the HL activity, 3) the lack of HL correlation to the TAG of HDL and HDL3.	Heparin	54-61	junctophilin 3	Homo sapiens	108-112	
1364970-5	1992	The in vivo acceleration of lipoprotein metabolism by heparin resulted in: 1) the reduction of VLDL-TAG and HDL2-TAG, and in the increase of HDL3-TAG, 2) the appearance of positive relation of HDL2-C to the LPL activity and of opposite relation to the HL activity, 3) the lack of HL correlation to the TAG of HDL and HDL3.	Heparin	54-61	junctophilin 3	Homo sapiens	193-197	
2151097-4	1990	The obtained results call attention to the importance of final concentration of Mn2+ ions at HDL2 precipitation with DS from heparin-Mn2+ supernate containing HDL.	Heparin	125-132	junctophilin 3	Homo sapiens	93-97	
2400395-7	1990	3H-labelled HDL2 and HDL3 subfractions behaved differently under the precipitant action of heparin-Mn2+; fraction C (the richest in apolipoprotein E) produced the largest amount of radioactive and chemical precipitate.	Heparin	91-98	junctophilin 3	Homo sapiens	12-16