PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33820486-3	2021	METHODS: We examined the effect of polyinosinic-polycytidylic acid (poly IC), an agonist of TLR3, on MCP-1, CCL5 and interferon (IFN)-beta expression in GECs.	Poly I-C	35-66	C-C motif chemokine ligand 2	Homo sapiens	101-106	
33820486-3	2021	METHODS: We examined the effect of polyinosinic-polycytidylic acid (poly IC), an agonist of TLR3, on MCP-1, CCL5 and interferon (IFN)-beta expression in GECs.	Poly I-C	68-75	C-C motif chemokine ligand 2	Homo sapiens	101-106	
31333667-4	2019	PolyI:C increased the expression of interferon-beta (IFN-beta), interleukin-6 (IL-6), interleukin-8 (IL-8), monocyte chemoattractant protein (MCP-1), and interleukin-1beta (IL-1beta) in HCT116 cells, and these up-regulations were significantly altered when cells were pre-stimulated with LAB isolated from Korean fermented foods.	Poly I-C	0-7	C-C motif chemokine ligand 2	Homo sapiens	142-147	
32221618-7	2020	Co-stimulation with poly I:C and LL-37 enhanced pro-inflammatory IL-6 and MCP-1 transcripts several fold compared to treatment with poly I:C or LL-37 alone.	Poly I-C	20-28	C-C motif chemokine ligand 2	Homo sapiens	74-79	
32221618-8	2020	Poly I:C increased IL-6 and MCP-1 protein production, and this effect was potentiated by LL-37.	Poly I-C	0-8	C-C motif chemokine ligand 2	Homo sapiens	28-33	
31049957-7	2019	RESULTS: Production of IL-6, IL-8, MCP-1, and OPG was significantly increased by Poly I:C or Pam3CSK4 to a similar extent.	Poly I-C	81-89	C-C motif chemokine ligand 2	Homo sapiens	35-40	
30295964-4	2018	RESULTS: Poly (I:C) induced the expression of the interferon-stimulated genes (ISG) MxA, OAS2 and APOBEC3G, and the cytokines MCP-1, IL-8, IL-6, CCL20, IFNbeta and RANTES by fibroblasts from all three sites.	Poly I-C	9-19	C-C motif chemokine ligand 2	Homo sapiens	126-131	
29632147-7	2018	Moreover, IRF3 activation by polyinosinic-polycytidylic acid augmented TNF-alpha-induced CCL2 secretion.	Poly I-C	29-60	C-C motif chemokine ligand 2	Homo sapiens	89-93	
24736562-4	2014	While PolyI:C induced maximal cytokine and chemokine production from both PHCEC (IFNgamma, CCL2, CCL3, and (CCL4), IL6, CXCL10, CCL5, TNFalpha) and PHKF (CCL2, IL-6, CXCL10, CCL5), only PHKF cytokines were inhibited by GCs.	Poly I-C	6-13	C-C motif chemokine ligand 2	Homo sapiens	91-95	
25055998-7	2015	We also found that poly-IC-induced mRNA expression of other proinflammatory mediators such as MCP-1, RANTES, and IL-8 was suppressed by licochalcone A.	Poly I-C	19-26	C-C motif chemokine ligand 2	Homo sapiens	94-99	
24736562-4	2014	While PolyI:C induced maximal cytokine and chemokine production from both PHCEC (IFNgamma, CCL2, CCL3, and (CCL4), IL6, CXCL10, CCL5, TNFalpha) and PHKF (CCL2, IL-6, CXCL10, CCL5), only PHKF cytokines were inhibited by GCs.	Poly I-C	6-13	C-C motif chemokine ligand 2	Homo sapiens	154-158	
28052863-5	2017	Poly(I:C) increased the production of IL-6, IL-8, monocyte chemoattractant protein-1, and ICAM-1.	Poly I-C	0-8	C-C motif chemokine ligand 2	Homo sapiens	50-84	
23542035-2	2013	We show that sustained LPS or poly(I:C)-stimulated MCP-1 production requires an IFNbeta-mediated feedback loop.	Poly I-C	30-39	C-C motif chemokine ligand 2	Homo sapiens	51-56	
22116002-6	2012	Poly(I:C) stimulated the secretion of IL-6, IL-8, MCP-1, RANTES, IP-10, eotaxin, MIP-1beta, and interferon-gamma, whereas zymosan triggered the production of IL-6, IL-8, and MCP-1.	Poly I-C	0-8	C-C motif chemokine ligand 2	Homo sapiens	50-55	
22762377-3	2012	While poly(I:C) induced IL-8 gene expression was solely inhibited by the NF-kappaB inhibitor III, MCP-1 gene induction was also blocked by PKA, p38 MAPK and JAK-STAT inhibitors.	Poly I-C	6-14	C-C motif chemokine ligand 2	Homo sapiens	98-103	
22762377-6	2012	These data are indicative for distinct signalling pathways in the poly(I:C)-induced gene expression of IL-8 and MCP-1 in HaCaT keratinocytes.	Poly I-C	66-75	C-C motif chemokine ligand 2	Homo sapiens	112-117	
22116002-6	2012	Poly(I:C) stimulated the secretion of IL-6, IL-8, MCP-1, RANTES, IP-10, eotaxin, MIP-1beta, and interferon-gamma, whereas zymosan triggered the production of IL-6, IL-8, and MCP-1.	Poly I-C	0-8	C-C motif chemokine ligand 2	Homo sapiens	174-179	
22116002-7	2012	LPS, poly(I:C), and zymosan thus each induced a distinct pattern of cytokine and chemokine release from human corneal fibroblasts, with the release of IL-6, IL-8, and MCP-1 being commonly elicited by all three agents.	Poly I-C	5-14	C-C motif chemokine ligand 2	Homo sapiens	167-172	
21715345-10	2011	A significant increase in expression levels of IL-6, TNF-alpha, IL-8, MCP-1, ICAM-1, and BFGF was observed after poly (I:C) RNA stimulation (P < 0.05).	Poly I-C	113-123	C-C motif chemokine ligand 2	Homo sapiens	70-75	
15265658-10	2004	Poly I:C treatment of RPE resulted in an increase in the production of IL-6, IL-8, MCP-1, and sICAM-1.	Poly I-C	0-8	C-C motif chemokine ligand 2	Homo sapiens	83-88	
21092943-4	2011	These mAbs bind the extracellular domain of mouse TLR3, inhibit poly(I:C)-induced activation of HEK293T cells transfected with mTLR3, and reduce poly(I:C)-induced production of CCL2 and CXCL10 by primary mouse embryonic fibroblasts.	Poly I-C	145-154	C-C motif chemokine ligand 2	Homo sapiens	177-181