PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24915573-3 2014 Intraluminal poly I:C induced rapid mucosal immune activation in C57BL/6 mice involving IFNbeta and the CXCL10/CXCR3 axis, that may drive inflammation towards a Th1 profile. Poly I-C 13-21 chemokine (C-X-C motif) ligand 10 Mus musculus 104-110 23051007-5 2013 Both poly I:C and LPS stimulation in porcine islets induced expression of chemokines (RANTES, MCP-1, IP-10, and IL-8), cytokines (IL-6 and type I interferons), and adhesion molecules (VCAM-1 and ICAM-1). Poly I-C 5-13 chemokine (C-X-C motif) ligand 10 Mus musculus 101-106 23454169-6 2013 KEY FINDINGS: PEITC suppressed the activation of IRF3 and the expression of IP-10 induced by lipopolysaccharide (LPS) or polyinosinic-polycytidylic acid (poly[I:C]). Poly I-C 121-152 chemokine (C-X-C motif) ligand 10 Mus musculus 76-81 20231782-12 2010 Significantly high levels of mouse IP-10 in BALB/c mice was also detected when SARS-CoV-infected mice were treated with the interferon inducer, polyriboinosinic-polyribocytidylic acid stabilized with poly-L-lysine and carboxymethyl cellulose (poly IC:LC). Poly I-C 144-183 chemokine (C-X-C motif) ligand 10 Mus musculus 35-40 16265667-4 2006 Our results show that the injection of polyinosinic-polycytidylic acid (poly(I:C)), a synthetic dsRNA, into the striatum of the mouse brain induces the activation of astrocytes and the expression of TNF-alpha, IFN-beta, and IP-10. Poly I-C 39-70 chemokine (C-X-C motif) ligand 10 Mus musculus 224-229 16265667-4 2006 Our results show that the injection of polyinosinic-polycytidylic acid (poly(I:C)), a synthetic dsRNA, into the striatum of the mouse brain induces the activation of astrocytes and the expression of TNF-alpha, IFN-beta, and IP-10. Poly I-C 72-81 chemokine (C-X-C motif) ligand 10 Mus musculus 224-229 15675953-4 2005 With regard to Th1-type chemokines, exogenous stimulus, such as interferon-gamma (IFN-gamma), lipopolysaccharide, or polyinosinic-polycytidylic acid, was mandatory for the production of substantial amounts of CXCL10, CXCL9, and CXCL11 both in LC and splenic DC. Poly I-C 117-148 chemokine (C-X-C motif) ligand 10 Mus musculus 209-215 27820939-5 2017 Activation of PAR-1 enhanced poly I:C induction of IFNbeta and CXCL10 expression in the murine macrophage cell line RAW264.7, bone-marrow derived mouse macrophages (BMM) and mouse splenocytes. Poly I-C 29-37 chemokine (C-X-C motif) ligand 10 Mus musculus 63-69 27820939-7 2017 We found that poly I:C treated PAR-1-/- mice and WT mice given the thrombin inhibitor dabigatran etexilate exhibited significantly less IFNbeta and CXCL10 expression in the spleen and plasma than WT mice. Poly I-C 14-22 chemokine (C-X-C motif) ligand 10 Mus musculus 148-154 33558485-9 2021 These observations were confirmed in OL primary cultures: cells treated with TLR3 agonist Poly(I:C) during differentiation showed a stronger upregulation of Ccl2 and Cxcl10 compared to cells treated during proliferation and led to decreased expression of myelin genes. Poly I-C 90-99 chemokine (C-X-C motif) ligand 10 Mus musculus 166-172 32265633-3 2020 injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 chemokine in the hippocampus. Poly I-C 30-61 chemokine (C-X-C motif) ligand 10 Mus musculus 99-105 32265633-3 2020 injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 chemokine in the hippocampus. Poly I-C 63-66 chemokine (C-X-C motif) ligand 10 Mus musculus 99-105 32265633-5 2020 The present study was undertaken to determine the role of CXCL10 in mediating the development of hyperexcitability in response to PIC challenge. Poly I-C 130-133 chemokine (C-X-C motif) ligand 10 Mus musculus 58-64 30691477-7 2019 Maternal polyI:C administration also increased embryonic brain chemokines, influenced by both maternal and embryonic genotype: CCL5 and CXCL10 levels were higher in embryonic brains from Map2k7 dams versus control dams; for CCL5, this was more pronounced in Map2k7 Hz embryos. Poly I-C 9-16 chemokine (C-X-C motif) ligand 10 Mus musculus 136-142 30691477-8 2019 Placental CXCL10 and CXCL12 levels were also elevated by polyI:C, the former enhanced and the latter suppressed, in placentae from maternal Map2k7 Hzs relative to control dams receiving polyI:C. Poly I-C 57-64 chemokine (C-X-C motif) ligand 10 Mus musculus 10-16 30691477-8 2019 Placental CXCL10 and CXCL12 levels were also elevated by polyI:C, the former enhanced and the latter suppressed, in placentae from maternal Map2k7 Hzs relative to control dams receiving polyI:C. Poly I-C 186-193 chemokine (C-X-C motif) ligand 10 Mus musculus 10-16 29541027-9 2018 Macrophage chemotaxis was induced by the supernatant of poly(I:C)-treated IEC which was consistent with the level of CXCL10 secreted. Poly I-C 56-65 chemokine (C-X-C motif) ligand 10 Mus musculus 117-123