PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2157662-7	1990	HPLC analysis of extracted supernatants of IL-1-treated PMNs demonstrated the release of leukotriene B4 (LTB4), its oxidative products, and 5-hydroxyeicosatetraenoic acid (5-HETE).	Leukotriene B4	89-103	interleukin 1 alpha	Homo sapiens	43-47	
2999234-2	1985	LTB4 enhanced IL 1 production by lipopolysaccharide (LPS)-stimulated monocytes twofold to threefold, and the most efficient concentrations of LTB4 were 10(-8) to 10(-7) M. LTD4 also enhanced IL 1 production, but to a lesser extent than LTB4.	Leukotriene B4	0-4	interleukin 1 alpha	Homo sapiens	14-18	
2999234-2	1985	LTB4 enhanced IL 1 production by lipopolysaccharide (LPS)-stimulated monocytes twofold to threefold, and the most efficient concentrations of LTB4 were 10(-8) to 10(-7) M. LTD4 also enhanced IL 1 production, but to a lesser extent than LTB4.	Leukotriene B4	0-4	interleukin 1 alpha	Homo sapiens	191-195	
2999234-4	1985	Similarly, IL 1 production by monocytes stimulated with the known IL 1 inducers muramyl dipeptide, silica, or zymosan was also enhanced by LTB4.	Leukotriene B4	139-143	interleukin 1 alpha	Homo sapiens	11-15	
2999234-4	1985	Similarly, IL 1 production by monocytes stimulated with the known IL 1 inducers muramyl dipeptide, silica, or zymosan was also enhanced by LTB4.	Leukotriene B4	139-143	interleukin 1 alpha	Homo sapiens	66-70	
32234475-5	2020	Dectin-1 also promotes inflammasome-dependent interleukin-1beta (IL-1beta) secretion through leukotriene B4 production.	Leukotriene B4	93-107	interleukin 1 alpha	Homo sapiens	65-73	
23194965-0	1996	Dose-dependent reversal effects of Capsaicin on Interleukin-1alpha production is associated with the metabolism of arachidonic acid (leukotriene B(4) and prostaglandin E(2)) as well as nitric oxide production in human leukocytes.	Leukotriene B4	133-146	interleukin 1 alpha	Homo sapiens	48-66	
2224944-2	1990	Interleukin-1 increases the concentration of prostaglandin E2 and leukotriene B4, metabolites of arachidonic acid, which are potent mediators of inflammation.	Leukotriene B4	66-80	interleukin 1 alpha	Homo sapiens	0-13	
34064821-6	2021	The enzymes 5-lipoxygenase and 12-lipoxygenase, which catalyze the synthesis of BLT1/2 ligands (LTB4, 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE), and 12-hydroxyheptadecatreinoic acid (12-HHT)), were also critically associated with the stimulation of NLRP3 and IL-1beta synthesis.	Leukotriene B4	96-100	interleukin 1 alpha	Homo sapiens	265-273