PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21196815-7	2011	Treatment with hexachlorophene (an inhibitor of beta-catenin) reduces the proliferation of pancreatic cells despite the presence of PAUF.	Hexachlorophene	15-30	catenin beta 1	Homo sapiens	48-60	
30525075-1	2018	Introduction: We previously reported that transplantation of hepatic cell sheets from human bone marrow-derived mesenchymal stem cells (BM-MSCs) with hexachlorophene, a Wnt/beta-catenin signaling inhibitor, ameliorated acute liver injury.	Hexachlorophene	150-165	catenin beta 1	Homo sapiens	173-185	
16735606-0	2006	Hexachlorophene inhibits Wnt/beta-catenin pathway by promoting Siah-mediated beta-catenin degradation.	Hexachlorophene	0-15	catenin beta 1	Homo sapiens	29-41	
19091460-0	2009	Hexachlorophene suppresses beta-catenin expression by up-regulation of Siah-1 in EBV-infected B lymphoma cells.	Hexachlorophene	0-15	catenin beta 1	Homo sapiens	27-39	
19091460-3	2009	Conversely, results from cell-based small molecule screening studies have shown that the antibiotic hexachlorophene can down-regulate beta-catenin in colon cancer cells.	Hexachlorophene	100-115	catenin beta 1	Homo sapiens	134-146	
19091460-4	2009	Here we report that hexachlorophene also counteracts the elevated beta-catenin levels in EBV-infected B lymphomas.	Hexachlorophene	20-35	catenin beta 1	Homo sapiens	66-78	
19091460-7	2009	The hexachlorophene modulation of Siah-1 and beta-catenin is independent of p53 and results in reduced expression of cyclin-D1 and c-Myc (target genes of beta-catenin), leading to the growth arrest of B lymphoma cells.	Hexachlorophene	4-19	catenin beta 1	Homo sapiens	45-57	
19091460-7	2009	The hexachlorophene modulation of Siah-1 and beta-catenin is independent of p53 and results in reduced expression of cyclin-D1 and c-Myc (target genes of beta-catenin), leading to the growth arrest of B lymphoma cells.	Hexachlorophene	4-19	catenin beta 1	Homo sapiens	154-166	
19091460-8	2009	From these results we propose that hexachlorophene may provide a novel therapeutic strategy for EBV-infected B lymphoma cells by reducing beta-catenin levels via the restoration of Siah-1.	Hexachlorophene	35-50	catenin beta 1	Homo sapiens	138-150	
16735606-0	2006	Hexachlorophene inhibits Wnt/beta-catenin pathway by promoting Siah-mediated beta-catenin degradation.	Hexachlorophene	0-15	catenin beta 1	Homo sapiens	77-89	
16735606-3	2006	In this study, we identified hexachlorophene as an inhibitor of Wnt/beta-catenin signaling from cell-based small-molecule screening.	Hexachlorophene	29-44	catenin beta 1	Homo sapiens	68-80	
16735606-4	2006	Hexachlorophene antagonized CRT that was stimulated by Wnt3a-conditioned medium by promoting the degradation of beta-catenin.	Hexachlorophene	0-15	catenin beta 1	Homo sapiens	112-124	
16735606-6	2006	In addition, hexachlorophene represses the expression of cyclin D1, which is a known beta-catenin target gene, and inhibits the growth of colon cancer cells.	Hexachlorophene	13-28	catenin beta 1	Homo sapiens	85-97	
16735606-7	2006	Our findings suggest that hexachlorophene attenuates Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.	Hexachlorophene	26-41	catenin beta 1	Homo sapiens	57-69	
16735606-7	2006	Our findings suggest that hexachlorophene attenuates Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.	Hexachlorophene	26-41	catenin beta 1	Homo sapiens	108-120