PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9142900-3	1997	DFMO also significantly reduced basal levels of TGF-beta mRNA in unwounded cells.	Eflornithine	0-4	transforming growth factor, beta 1	Rattus norvegicus	48-56	
11003584-10	2000	These results indicate that 1) depletion of cellular polyamines by DFMO increases expression of the TGF-betaRI gene and 2) increased TGF-betaRI expression plays an important role in the process through which polyamine depletion sensitizes intestinal epithelial cells to growth inhibition induced by TGF-beta.	Eflornithine	67-71	transforming growth factor, beta 1	Rattus norvegicus	100-108	
9142900-9	1997	In the presence of DFMO, exogenous TGF-beta restored cell migration to normal.	Eflornithine	19-23	transforming growth factor, beta 1	Rattus norvegicus	35-43	
9688614-5	1998	Administration of DFMO not only depleted intracellular polyamines but also significantly increased the mRNA levels of TGF-beta.	Eflornithine	18-22	transforming growth factor, beta 1	Rattus norvegicus	118-126	
9688614-6	1998	Increased TGF-beta mRNA in DFMO-treated cells was paralleled by an increase in TGF-beta content.	Eflornithine	27-31	transforming growth factor, beta 1	Rattus norvegicus	10-18	
9688614-6	1998	Increased TGF-beta mRNA in DFMO-treated cells was paralleled by an increase in TGF-beta content.	Eflornithine	27-31	transforming growth factor, beta 1	Rattus norvegicus	79-87	
9688614-8	1998	The half-life of mRNA for TGF-beta in normal cells was approximately 65 min and increased to >16 h in cells treated with DFMO for 6 or 12 days.	Eflornithine	124-128	transforming growth factor, beta 1	Rattus norvegicus	26-34	
9688614-9	1998	Exogenous polyamine, when given together with DFMO, prevented the increased half-life of TGF-beta mRNA in IEC-6 cells.	Eflornithine	46-50	transforming growth factor, beta 1	Rattus norvegicus	89-97	
9142900-4	1997	Gene expression of TGF-beta was dramatically stimulated after wounding of a monolayer of cells not treated with DFMO.	Eflornithine	112-116	transforming growth factor, beta 1	Rattus norvegicus	19-27	
9142900-7	1997	Depletion of intracellular polyamines in DFMO-treated cells significantly inhibited increased expression of the TGF-beta gene in response to wounding.	Eflornithine	41-45	transforming growth factor, beta 1	Rattus norvegicus	112-120	
9142900-10	1997	These results indicate that 1) polyamine depletion induced by DFMO is associated with decreases in the expression of the TGF-beta gene and cell migration in IEC-6 cells and 2) exogenous TGF-beta reverses the inhibitory effect of polyamine depletion on cell migration.	Eflornithine	62-66	transforming growth factor, beta 1	Rattus norvegicus	121-129	
9142900-10	1997	These results indicate that 1) polyamine depletion induced by DFMO is associated with decreases in the expression of the TGF-beta gene and cell migration in IEC-6 cells and 2) exogenous TGF-beta reverses the inhibitory effect of polyamine depletion on cell migration.	Eflornithine	62-66	transforming growth factor, beta 1	Rattus norvegicus	186-194