PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15007625-4 2004 We exploited the power of yeast genetics to isolate for the first time several bleomycin-resistant mutants derived from a strain deleted for the IMP2 gene encoding a transcriptional co-activator. Bleomycin 79-88 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 145-149 14558142-7 2003 Moreover, the interaction between IMP2 and GAL6/BLH1, a recently isolated gene involved in the regulation of GAL genes that shares with Imp2 the ability to protect cells from the glycopeptide bleomycin, was also analysed. Bleomycin 192-201 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 34-38 14558142-7 2003 Moreover, the interaction between IMP2 and GAL6/BLH1, a recently isolated gene involved in the regulation of GAL genes that shares with Imp2 the ability to protect cells from the glycopeptide bleomycin, was also analysed. Bleomycin 192-201 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 136-140 8628275-0 1996 The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants. Bleomycin 129-138 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 29-33 10546901-3 1999 In the yeast Saccharomyces cerevisiae, the transcriptional activator Imp2 is required to fend off the toxic effects of bleomycin. Bleomycin 119-128 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 69-73 10546901-4 1999 However, it remains unclear whether Imp2 controls the expression of a protein that either repairs bleomycin-induced DNA lesions, or detoxifies the drug, and or both. Bleomycin 98-107 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 36-40 8628275-4 1996 A DNA clone containing the IMP2 gene that complemented the most sensitive bleomycin mutant was identified. Bleomycin 74-83 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 27-31 8628275-5 1996 A role for IMP2 in defense against the toxic effects of bleomycin has not been previously reported. Bleomycin 56-65 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 11-15 8628275-6 1996 imp2 null mutants were constructed and were found to be 15-fold more sensitive to bleomycin than wild-type strains. Bleomycin 82-91 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 0-4 24599794-0 2014 Upregulation of the Saccharomyces cerevisiae efflux pump Tpo1 rescues an Imp2 transcription factor-deficient mutant from bleomycin toxicity. Bleomycin 121-130 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 73-77 24599794-1 2014 Yeast mutants lacking the transcriptional co-activator Imp2 are hypersensitive to the anticancer drug bleomycin, although the gene targets involved in this process remain elusive. Bleomycin 102-111 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 55-59