PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32729248-8 2020 Further top ACE2 regulators in vivo or in primary cells include erlotinib and bleomycin in the lung and vancomycin, cisplatin, and probenecid in the kidney. Bleomycin 78-87 angiotensin converting enzyme 2 Homo sapiens 12-16 18441099-9 2008 Moreover, purified recombinant human ACE-2, delivered to mice systemically by osmotic minipump, attenuated bleomycin-induced lung collagen accumulation. Bleomycin 107-116 angiotensin converting enzyme 2 Homo sapiens 37-42 33706759-8 2021 ACE2 and TMPRSS2 were also expressed in FSP-1+ lung fibroblasts in bleomycin-induced pulmonary fibrosis, and when combined with PM exposure, they were further upregulated. Bleomycin 67-76 angiotensin converting enzyme 2 Homo sapiens 0-4 25435005-0 2015 Therapeutic effect of human umbilical cord mesenchymal stem cells modified by angiotensin-converting enzyme 2 gene on bleomycin-induced lung fibrosis injury. Bleomycin 118-127 angiotensin converting enzyme 2 Homo sapiens 78-109 29731719-8 2018 ACE2 or vehicle was administered via osmotic pump for the final 2 weeks, beginning 3 weeks after bleomycin. Bleomycin 97-106 angiotensin converting enzyme 2 Homo sapiens 0-4 29731719-13 2018 Conclusion: Collectively, our findings enumerate that ACE2 treatment improved pulmonary vascular muscularization following bleomycin exposure, concomitant with increased SOD2 expression. Bleomycin 123-132 angiotensin converting enzyme 2 Homo sapiens 54-58 25435005-1 2015 The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin-converting enzyme 2 gene (ACE2; ACE2-uMSCs) on bleomycin (BLM)-induced lung injury and pulmonary fibrosis in mice. Bleomycin 202-211 angiotensin converting enzyme 2 Homo sapiens 143-174 25435005-1 2015 The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin-converting enzyme 2 gene (ACE2; ACE2-uMSCs) on bleomycin (BLM)-induced lung injury and pulmonary fibrosis in mice. Bleomycin 202-211 angiotensin converting enzyme 2 Homo sapiens 181-185 25435005-1 2015 The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin-converting enzyme 2 gene (ACE2; ACE2-uMSCs) on bleomycin (BLM)-induced lung injury and pulmonary fibrosis in mice. Bleomycin 202-211 angiotensin converting enzyme 2 Homo sapiens 187-191 25435005-1 2015 The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin-converting enzyme 2 gene (ACE2; ACE2-uMSCs) on bleomycin (BLM)-induced lung injury and pulmonary fibrosis in mice. Bleomycin 213-216 angiotensin converting enzyme 2 Homo sapiens 143-174 25435005-1 2015 The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin-converting enzyme 2 gene (ACE2; ACE2-uMSCs) on bleomycin (BLM)-induced lung injury and pulmonary fibrosis in mice. Bleomycin 213-216 angiotensin converting enzyme 2 Homo sapiens 181-185 25435005-1 2015 The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin-converting enzyme 2 gene (ACE2; ACE2-uMSCs) on bleomycin (BLM)-induced lung injury and pulmonary fibrosis in mice. Bleomycin 213-216 angiotensin converting enzyme 2 Homo sapiens 187-191 25435005-6 2015 In conclusion, the results of the present study demonstrated that ACE2 and uMSCs had a synergistic therapeutic effect on bleomycin-induced acute lung injury. Bleomycin 121-130 angiotensin converting enzyme 2 Homo sapiens 66-70 25089563-10 2015 In vivo, constant infusion with Ang(1-7) or intratracheal instillation with lenti-ACE2 shifted the RAS balance toward the ACE2/Ang(1-7)/Mas axis, alleviated bleomycin-induced lung fibrosis, and inhibited the RhoA/Rock pathway by reducing NOX4-derived ROS. Bleomycin 157-166 angiotensin converting enzyme 2 Homo sapiens 82-86 24168260-4 2014 We hypothesized that up-regulation of the ACE2/Ang-(1-7)/Mas axis protects against bleomycin (BLM)-induced pulmonary fibrosis by inhibiting the mitogen-activated protein kinase (MAPK)/NF-kappaB pathway. Bleomycin 83-92 angiotensin converting enzyme 2 Homo sapiens 42-46 24168260-4 2014 We hypothesized that up-regulation of the ACE2/Ang-(1-7)/Mas axis protects against bleomycin (BLM)-induced pulmonary fibrosis by inhibiting the mitogen-activated protein kinase (MAPK)/NF-kappaB pathway. Bleomycin 94-97 angiotensin converting enzyme 2 Homo sapiens 42-46