PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31631444-10 2020 Furthermore, the expressions of senescence markers, such as p21 and p53, were upregulated upon bleomycin treatment, thereby intensifying the fibrotic condition. Bleomycin 95-104 H3 histone pseudogene 16 Homo sapiens 60-63 29348392-4 2018 The senescence-associated beta-galactosidase activity, the protein expression of P16 and P21, and inflammatory-related marker gene levels IL-1beta, IL-6, and TNF-alpha were increased in bleomycin-treated AFSCs in a dose-dependent manner. Bleomycin 186-195 H3 histone pseudogene 16 Homo sapiens 89-92 29779106-0 2018 Modular Nanotransporter with P21 Fragment Inhibits DNA Repair after Bleomycin Treatment. Bleomycin 68-77 H3 histone pseudogene 16 Homo sapiens 29-32 29779106-2 2018 This p21 fragment in MNT can significantly inhibit DNA repair in A431 human carcinoma cells after bleomycin treatment. Bleomycin 98-107 H3 histone pseudogene 16 Homo sapiens 5-8 29348392-5 2018 Rapamycin treatment decreased the gene expression of MMP-3, MMP-13, IL-1beta, IL-6, TNF-alpha, and protein levels of P16 and P21 in bleomycin-treated AFSCs. Bleomycin 132-141 H3 histone pseudogene 16 Homo sapiens 125-128 17662641-3 2007 We show that bleomycin-treated A549 cells exhibit: senescence-like cell morphology; a senescence-associated increase in SA-beta-galactosidase activity; cell cycle arrest; and upregulation of p53 and p21. Bleomycin 13-22 H3 histone pseudogene 16 Homo sapiens 199-202 17662641-6 2007 Our results support the hypothesis that downregulation of caveolin-1 expression affects bleomycin-induced cell cycle arrest and subsequent cellular senescence that is driven by p53 and p21. Bleomycin 88-97 H3 histone pseudogene 16 Homo sapiens 185-188