PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30450979-1 2018 Ephrin type-A receptor 2 (EphA2) is a transmembrane receptor which is upregulated in injured lungs, including those treated with bleomycin. Bleomycin 129-138 Eph receptor A2 Mus musculus 0-24 30450979-1 2018 Ephrin type-A receptor 2 (EphA2) is a transmembrane receptor which is upregulated in injured lungs, including those treated with bleomycin. Bleomycin 129-138 Eph receptor A2 Mus musculus 26-31 28743499-0 2017 All-trans retinoic acid attenuates bleomycin-induced pulmonary fibrosis via downregulating EphA2-EphrinA1 signaling. Bleomycin 35-44 Eph receptor A2 Mus musculus 91-96 28743499-6 2017 Furthermore, bleomycin upregulated EphA2, EphrinA1, PI3K 110gamma, Akt, IL-6 and TNF-alpha. Bleomycin 13-22 Eph receptor A2 Mus musculus 35-40 28743499-7 2017 However, administration of ATRA attenuated the upregulation of EphA2-EphrinA1 and PI3K-Akt after bleomycin instillation, and decreased pulmonary fibrosis. Bleomycin 97-106 Eph receptor A2 Mus musculus 63-68 28743499-9 2017 Collectively, these data suggest that ATRA attenuates bleomycin-induced pulmonary fibrosis by regulating EphA2-EphrinA1 and PI3K-Akt signaling. Bleomycin 54-63 Eph receptor A2 Mus musculus 105-110 21799118-0 2012 Eph-A2 promotes permeability and inflammatory responses to bleomycin-induced lung injury. Bleomycin 59-68 Eph receptor A2 Mus musculus 0-6 21799118-6 2012 In early bleomycin injury in WT mice, the expression of both EphA2 and ephrin-A1 increased. Bleomycin 9-18 Eph receptor A2 Mus musculus 61-66 21799118-8 2012 Bleomycin caused less accumulation of lung leukocytes in EphA2 KO animals than in WT animals, suggesting that EphA2 regulates inflammation. Bleomycin 0-9 Eph receptor A2 Mus musculus 57-62 21799118-8 2012 Bleomycin caused less accumulation of lung leukocytes in EphA2 KO animals than in WT animals, suggesting that EphA2 regulates inflammation. Bleomycin 0-9 Eph receptor A2 Mus musculus 110-115 21799118-10 2012 After bleomycin injury, EphA2 KO animals produced less CXCL1 and CCL2 than WT animals. Bleomycin 6-15 Eph receptor A2 Mus musculus 24-29