PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24266925-7 2013 Deletion of CD39 and/or CD73 decreased the collagen content, and prevented skin thickening and tensile strength increase after bleomycin challenge. Bleomycin 127-136 5' nucleotidase, ecto Mus musculus 24-28 16547283-0 2006 Ecto-5"-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury. Bleomycin 93-102 5' nucleotidase, ecto Mus musculus 0-20 16547283-0 2006 Ecto-5"-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury. Bleomycin 93-102 5' nucleotidase, ecto Mus musculus 22-26 16547283-6 2006 Results demonstrated that CD73(-/-) mice challenged with bleomycin no longer accumulated adenosine in their lungs, suggesting that the primary means of adenosine production following bleomycin injury resulted from the release and subsequent dephosphorylation of adenine nucleotides. Bleomycin 57-66 5' nucleotidase, ecto Mus musculus 26-30 16547283-6 2006 Results demonstrated that CD73(-/-) mice challenged with bleomycin no longer accumulated adenosine in their lungs, suggesting that the primary means of adenosine production following bleomycin injury resulted from the release and subsequent dephosphorylation of adenine nucleotides. Bleomycin 183-192 5' nucleotidase, ecto Mus musculus 26-30 16547283-7 2006 CD73(-/-) mice challenged with bleomycin exhibited enhanced pulmonary inflammation and fibrosis as well as exaggerated expression of proinflammatory and profibrotic mediators in the lung. Bleomycin 31-40 5' nucleotidase, ecto Mus musculus 0-4 16547283-8 2006 Intranasal instillations of exogenous nucleotidase restored the ability of lungs of CD73(-/-) mice to accumulate adenosine following bleomycin challenge. Bleomycin 133-142 5' nucleotidase, ecto Mus musculus 84-88 16547283-10 2006 CD73(+/+) animals challenged with bleomycin and supplemented with exogenous nucleotidase also exhibited reduced inflammation. Bleomycin 34-43 5' nucleotidase, ecto Mus musculus 0-4 16547283-11 2006 Together, these findings suggest that CD73-dependent adenosine production contributes to anti-inflammatory pathways in bleomycin-induced lung injury. Bleomycin 119-128 5' nucleotidase, ecto Mus musculus 38-42