PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35548340-0 2022 An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-kappaB/TNF-alpha Signaling in Macrophages. Bleomycin 29-38 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 89-98 24300094-15 2013 Our findings indicate that andrographolide compromised bleomycin-induced pulmonary inflammation and fibrosis possibly through inactivation of NF-kappaB. Bleomycin 55-64 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 142-151 23562440-7 2013 In a model of bleomycin-induced skin fibrosis, Nfkb1(-/-) and c-Rel(-/-) mice displayed opposite phenotypes, with c-Rel(-/-) mice being protected and Nfkb1(-/-) developing more fibrosis than wild-type mice. Bleomycin 14-23 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 47-52 12140739-7 2002 We determined the effect of cytoplasmic NFkappaB decoys on bleomycin-induced inflammation. Bleomycin 59-68 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 40-48 11029377-0 2000 Antisense oligonucleotides to NF-kappaB improve survival in bleomycin-induced pneumopathy of the mouse. Bleomycin 60-69 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 30-39 11029377-1 2000 We examined the effect of antisense oligonucleotides to the p65 subunit of NF-kappaB on the survival of bleomycin (BLM)-induced pneumonitis in C57BL/6 mice (female, 8 wk of age, 17 to 20 g body weight). Bleomycin 104-113 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 75-84 35548340-15 2022 Conclusion: Fuzheng Huayu formula has a good effect against pulmonary fibrosis induced by bleomycin in mice, whose action mechanism was associated with down-regulation of NF-kappaB/TNF-alpha signaling pathway in pro-inflammatory macrophages. Bleomycin 90-99 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 171-180 32390869-0 2020 Protein Kinase C delta (PKCdelta) Attenuates Bleomycin Induced Pulmonary Fibrosis via Inhibiting NF-kappaB Signaling Pathway. Bleomycin 45-54 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 97-106 33290968-0 2021 Pinocembrin relieves lipopolysaccharide and bleomycin induced lung inflammation via inhibiting TLR4-NF-kappaB-NLRP3 inflammasome signaling pathway. Bleomycin 44-53 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 100-109 33027868-0 2020 The Effects of Chronic Intermittent Hypoxia in Bleomycin-induced lung injury on Pulmonary Fibrosis via Regulating the NF-kappaB/Nrf2 Signaling Pathway. Bleomycin 47-56 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 118-127 35178456-6 2022 Histopathological changes, inflammatory factors (IL-6, IL-1beta, and TNF-alpha), and the proteins of the TLR4/MyD88/NF-kappaB pathway in bleomycin- (BLM-) induced mice model were examined by hematoxylin-eosin (H&E), Masson or immunohistochemistry staining, Western blot, and enzyme-linked immunosorbent assay analysis. Bleomycin 137-146 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 116-125 33092214-9 2020 The underlying mechanisms for the protective effect of MI-2 bleomycin induced pulmonary fibrosis may be attributed to its inhibition on NF-kappaB pathway. Bleomycin 60-69 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 136-145 30918525-10 2019 Conclusion: CAE effectively delayed the progression of BLM-induced pulmonary fibrosis in pulmonary fibrosis mice and a possible mechanism is the inhibition of cell apoptosis of NF-kappaB/p38-mediated signaling pathway. Bleomycin 55-58 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 177-186 31940650-12 2020 CONCLUSION: GAA has protective effect on BLM-induced lung injury, and TGF-beta/Smad-3/NF-kappaB signaling pathway may play an important role in the pathogenesis of BLM-induced lung injury. Bleomycin 164-167 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 86-95 30928090-0 2019 S-allyl-l-cysteine attenuates bleomycin-induced pulmonary fibrosis and inflammation via AKT/NF-kappaB signaling pathway in mice. Bleomycin 30-39 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 92-101 29393339-8 2018 Furthermore, the NALP3 inflammasome was found to be activated in bleomycin-induced pulmonary fibrosis in mice, and this activation was relieved by a nuclear factor (NF)-kappaB inhibitor. Bleomycin 65-74 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 149-175 30367690-0 2018 Withaferin A attenuates bleomycin-induced scleroderma by targeting FoxO3a and NF-kappabeta signaling: Connecting fibrosis and inflammation. Bleomycin 24-33 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 78-90 29849916-12 2018 The present study suggested that gefitinib could alleviate lung fibrosis through the HMGB1/NOXs-ROS/EGFR-MAPKs-AP-1/NF-kappaB signal in bleomycin-induced pulmonary fibrosis. Bleomycin 136-145 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 116-125 25455454-8 2015 Moreover, BLM-induced pulmonary nuclear factor kappa B (NF-kappaB) p65 activation was blocked by PBA. Bleomycin 10-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 32-54 29456817-0 2018 S100A9 aggravates bleomycin-induced dermal fibrosis in mice via activation of ERK1/2 MAPK and NF-kappaB pathways. Bleomycin 18-27 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 94-103 26520185-10 2016 Moreover, BLM-induced nuclear translocation of nuclear factor kappa B (NF-kappaB) p65 was blocked by calcitriol. Bleomycin 10-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 47-69 26520185-10 2016 Moreover, BLM-induced nuclear translocation of nuclear factor kappa B (NF-kappaB) p65 was blocked by calcitriol. Bleomycin 10-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 71-80 25455454-8 2015 Moreover, BLM-induced pulmonary nuclear factor kappa B (NF-kappaB) p65 activation was blocked by PBA. Bleomycin 10-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 56-65 25664028-10 2014 CONCLUSION: our study suggests the potential in prevention of bleomycin-induced pulmonary fibrosis with NF-kappaB p65 antisense oligonucleotide. Bleomycin 62-71 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 104-113 25111852-0 2014 Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-kappaB in mice. Bleomycin 35-44 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 103-112 25111852-16 2014 Our data found that BLM-induced lung inflammation and pulmonary fibrosis were significantly alleviated by GLP-1 treatment in mice, possibly through inactivation of NF-kappaB. Bleomycin 20-23 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 164-173 24584660-1 2014 To investigate the influence of NF-kappaB antisense oligonucleotide on transdifferentiation of fibroblast in the pathological process of bleomycin-induced pulmonary fibrosis in mice. Bleomycin 137-146 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 32-41 24584660-11 2014 NF-kappaB antisense oligonucleotide can inhibit the transdifferentiation of fibroblast towards myofibroblast in the pathological process of bleomycin-induced pulmonary fibrosis in mice. Bleomycin 140-149 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 0-9