PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17992263-6 2007 Exogenous rIL-1beta recapitulated a high degree of bleomycin-induced lung pathology, and specific blockade of IL-1R1 by IL-1 receptor antagonist dramatically reduced bleomycin-induced inflammation. Bleomycin 166-175 interleukin 1 receptor, type I Mus musculus 110-116 17992263-8 2007 In conclusion, bleomycin-induced lung pathology required the inflammasome and IL-1R1/MyD88 signaling, and IL-1 represented a critical effector of pathology and therapeutic target of chronic lung inflammation and fibrosis. Bleomycin 15-24 interleukin 1 receptor, type I Mus musculus 78-84 27306439-15 2016 This study demonstrated that FD, attenuates BLM-induced pulmonary inflammation and fibrosis in mice via inhibiting the activation of NALP3 inflammasome and the IL-1beta/IL-1R1/MyD88/ NF-kappaB pathway. Bleomycin 44-47 interleukin 1 receptor, type I Mus musculus 169-175 24172847-6 2014 Finally, Il1r1-/- and Il1a-/- mice exhibit reduced bronchoalveolar lavage (BAL) neutrophilia and collagen deposition in response to bleomycin treatment. Bleomycin 132-141 interleukin 1 receptor, type I Mus musculus 9-14