PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31387171-4	2019	We found that angiotensin-converting enzyme 2 (ACE2) /Ang-(1-7)/MasR were decreased in the lungs of mice with IPF induced by bleomycin, and were negatively correlated with Tgfb1 mRNA expression.	Bleomycin	125-134	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	14-45	
31387171-4	2019	We found that angiotensin-converting enzyme 2 (ACE2) /Ang-(1-7)/MasR were decreased in the lungs of mice with IPF induced by bleomycin, and were negatively correlated with Tgfb1 mRNA expression.	Bleomycin	125-134	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	47-51	
25435005-4	2015	ACE2-uMSC injection following bleomycin pretreatment significantly alleviated lung injury in mice.	Bleomycin	30-39	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	0-4	
29731719-5	2018	Although previous studies suggest that administration of ACE2 prevents PH secondary to bleomycin-induced murine IPF, it is unknown whether ACE2 can reverse or treat existing disease.	Bleomycin	87-96	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	57-61	
27550926-2	2017	We evaluate the effects of pharmacological treatment with an angiotensin-converting enzyme 2 activator drug, associated with exercise, on the pulmonary lesions induced by bleomycin.	Bleomycin	171-180	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	61-92	
28316159-6	2017	Wild type and ACE2 over-expressing mice were instilled with bleomycin endotracheally (3.5 mg/kg) or the same volume saline.	Bleomycin	60-69	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	14-18	
28316159-16	2017	In bleomycin induced lung fibrosis in mice, ACE2(+ /+) -BLM mice exhibited milder lung fibrosis and lower NOX4 protein level but higher LC3-IIprotein level compared with WT-BLM mice.	Bleomycin	3-12	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	44-48	
18441099-6	2008	In mice exposed to low doses of bleomycin, lung collagen accumulation was enhanced by intratracheal administration of either ACE-2-specific small interfering RNAs (siRNAs) or the peptide DX(600), a competitive inhibitor of ACE-2 (P<0.05).	Bleomycin	32-41	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	125-130	
25998889-0	2015	Angiotensin-Converting Enzyme 2 Attenuates Bleomycin-Induced Lung Fibrosis in Mice.	Bleomycin	43-52	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	0-31	
25998889-10	2015	RESULTS: Exogenous ACE2 attenuated bleomycin-induced lung fibrosis by reversing the reduction of local ACE2 and by suppressing the elevation of AGT.	Bleomycin	35-44	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	19-23	
25998889-10	2015	RESULTS: Exogenous ACE2 attenuated bleomycin-induced lung fibrosis by reversing the reduction of local ACE2 and by suppressing the elevation of AGT.	Bleomycin	35-44	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	103-107	
25998889-13	2015	CONCLUSION: ACE2 attenuated bleomycin-induced lung fibrosis as an anti-inflammatory anti-apoptotic and anti-fibrotic agent, and it might be a promising therapeutic target for IPF.	Bleomycin	28-37	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	12-16	
22246130-0	2012	Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury.	Bleomycin	42-51	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	0-31	
22246130-5	2012	We hypothesized that ACE2 prevents Bleomycin (BLM)-induced lung injury.	Bleomycin	35-44	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	21-25	
22246130-5	2012	We hypothesized that ACE2 prevents Bleomycin (BLM)-induced lung injury.	Bleomycin	46-49	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	21-25	
18441099-6	2008	In mice exposed to low doses of bleomycin, lung collagen accumulation was enhanced by intratracheal administration of either ACE-2-specific small interfering RNAs (siRNAs) or the peptide DX(600), a competitive inhibitor of ACE-2 (P<0.05).	Bleomycin	32-41	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	223-228	
18441099-7	2008	Administration of either ACE-2 siRNA or DX(600) significantly increased the ANG II content of mouse lung tissue above the level induced by bleomycin alone.	Bleomycin	139-148	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	25-30