PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21811007-9 2011 Using transient transfection, we demonstrated that KuEnls is able to bind laser damage in the nucleus of Ku80-deficient cells within 10 sec and remains bound for up to 2 h. The Mt-Ku fusion protein was over-expressed in U2OS cells and this increased the sensitivity of the cells to bleomycin sulfate. Bleomycin 282-299 X-ray repair cross complementing 5 Homo sapiens 105-109 33217428-6 2020 Interestingly, the mutation of the equivalent residue in human Ku80 increases sensitivity to bleomycin in several cancer cell lines, suggesting that this mechanism is conserved in humans. Bleomycin 93-102 X-ray repair cross complementing 5 Homo sapiens 63-67 28780472-3 2017 The purpose of this study was to evaluate the effect of 50-Hz electromagnetic field (EMF) in combination with CDDP and bleomycin (Bleo) on expression of some of DNA repair genes (GADD45A, XRCC1, XRCC4, Ku70, Ku80, DNA-PKcs and LIG4) in MCF-7 (breast cancer) and SH-SY5Y (neuroblastoma) cell lines. Bleomycin 119-128 X-ray repair cross complementing 5 Homo sapiens 208-212 28780472-3 2017 The purpose of this study was to evaluate the effect of 50-Hz electromagnetic field (EMF) in combination with CDDP and bleomycin (Bleo) on expression of some of DNA repair genes (GADD45A, XRCC1, XRCC4, Ku70, Ku80, DNA-PKcs and LIG4) in MCF-7 (breast cancer) and SH-SY5Y (neuroblastoma) cell lines. Bleomycin 130-134 X-ray repair cross complementing 5 Homo sapiens 208-212 24811221-0 2014 Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway. Bleomycin 137-146 X-ray repair cross complementing 5 Homo sapiens 89-93 24811221-0 2014 Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway. Bleomycin 137-146 X-ray repair cross complementing 5 Homo sapiens 94-99 24137007-4 2014 In this report, we show that time-dependent kinetics of the NHEJ factors Ku80 and DNA-dependent protein kinase catalytic subunits (DNA-PKcs) in response to IR and bleomycin can be quantified by Number and Brightness analysis and Raster-scan Image Correlation Spectroscopy. Bleomycin 163-172 X-ray repair cross complementing 5 Homo sapiens 73-77 24137007-5 2014 Fluorescent-tagged Ku80 and DNA-PKcs quickly mobilized in response to IR and bleomycin treatments consistent with prior reports using laser-generated DSBs. Bleomycin 77-86 X-ray repair cross complementing 5 Homo sapiens 19-23 12384553-0 2002 An antisense oligonucleotide targeted to human Ku86 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agents. Bleomycin 129-138 X-ray repair cross complementing 5 Homo sapiens 47-51 12384553-5 2002 Moreover, transfection of M059K cells with Ku86 antisense ASOs markedly increased cell death after treatment with ionizing radiation, bleomycin, and etoposide. Bleomycin 134-143 X-ray repair cross complementing 5 Homo sapiens 43-47 11086072-7 2000 Furthermore, MM cells with Ku86v have increased sensitivity to irradiation, mitomycin C, and bleomycin compared with patient MM cells or normal bone marrow donor cells with Ku86. Bleomycin 93-102 X-ray repair cross complementing 5 Homo sapiens 27-32 11086072-7 2000 Furthermore, MM cells with Ku86v have increased sensitivity to irradiation, mitomycin C, and bleomycin compared with patient MM cells or normal bone marrow donor cells with Ku86. Bleomycin 93-102 X-ray repair cross complementing 5 Homo sapiens 27-31