PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7682247-5	1993	The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin.	Bleomycin	157-166	interleukin 6	Homo sapiens	23-26	
10090171-8	1999	The cellular release of IL-1beta, TNF-alpha, and IL-6 was elevated in response to bleomycin exposure in both controls and patients with SSc.	Bleomycin	82-91	interleukin 6	Homo sapiens	49-53	
7682247-2	1993	The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE).	Bleomycin	89-98	interleukin 6	Homo sapiens	15-32	
34220507-8	2021	Significantly, our results showed that Myricetin has potent effect on bleomycin-induced pulmonary inflammation by inhibiting the infiltration of inflammatory cells and the secretion of inflammatory cytokines IL-6, IL-1alpha, TNF-alpha and IFN-gamma.	Bleomycin	70-79	interleukin 6	Homo sapiens	208-212	
7682247-2	1993	The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE).	Bleomycin	89-98	interleukin 6	Homo sapiens	34-37	
7682247-3	1993	Heat (45 degrees C, 10 min) and exposure to 1 micrograms/ml bleomycin for 1 h at 37 degrees C induced similar levels of HSF binding in all four cell lines.	Bleomycin	60-69	interleukin 6	Homo sapiens	120-123	
7682247-4	1993	We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding.	Bleomycin	20-29	interleukin 6	Homo sapiens	113-116	
7682247-4	1993	We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding.	Bleomycin	67-76	interleukin 6	Homo sapiens	113-116	
7682247-5	1993	The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin.	Bleomycin	98-107	interleukin 6	Homo sapiens	23-26	
7682247-6	1993	The amount of activated HSF was directly proportional to the time elapsed since bleomycin treatment.	Bleomycin	80-89	interleukin 6	Homo sapiens	24-27	
7682247-7	1993	Our results therefore indicate no difference between CHO and its bleomycin-sensitive derivatives in the ability to initiate the heat shock response as determined by the production of activated HSF in response to either heat or bleomycin.	Bleomycin	227-236	interleukin 6	Homo sapiens	193-196	
26209236-8	2015	These changes were accompanied by an attenuation of BLM-induced elevations in pulmonary levels of profibrotic cytokines interleukin-6, monocyte chemoattractant protein-1, and transforming growth factor-beta (TGF-beta).	Bleomycin	52-55	interleukin 6	Homo sapiens	120-133	
29348392-4	2018	The senescence-associated beta-galactosidase activity, the protein expression of P16 and P21, and inflammatory-related marker gene levels IL-1beta, IL-6, and TNF-alpha were increased in bleomycin-treated AFSCs in a dose-dependent manner.	Bleomycin	186-195	interleukin 6	Homo sapiens	148-152	
29348392-5	2018	Rapamycin treatment decreased the gene expression of MMP-3, MMP-13, IL-1beta, IL-6, TNF-alpha, and protein levels of P16 and P21 in bleomycin-treated AFSCs.	Bleomycin	132-141	interleukin 6	Homo sapiens	78-82	
23526221-8	2013	We observed significant up-regulation of IL-1beta and IL-6 in bronchoalveolar lavage fluid (BALF) in bleomycin-induced lung fibrosis in vivo.	Bleomycin	101-110	interleukin 6	Homo sapiens	54-58	
23526221-9	2013	Importantly, primary fibrotic ATII cells isolated from lungs subjected to bleomycin secreted enhanced IL-1beta and IL-6 in vitro.	Bleomycin	74-83	interleukin 6	Homo sapiens	115-119	
20725963-1	2010	The formation of hypertrophic scars (HSF) is a frequent medical outcome of wound repair and often requires further therapy with treatments such as silicone gel sheets (SGS) or apoptosis-inducing agents, including bleomycin.	Bleomycin	213-222	interleukin 6	Homo sapiens	37-40