PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7682247-5 1993 The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin. Bleomycin 157-166 interleukin 6 Homo sapiens 23-26 26209236-8 2015 These changes were accompanied by an attenuation of BLM-induced elevations in pulmonary levels of profibrotic cytokines interleukin-6, monocyte chemoattractant protein-1, and transforming growth factor-beta (TGF-beta). Bleomycin 52-55 interleukin 6 Homo sapiens 120-133 34220507-8 2021 Significantly, our results showed that Myricetin has potent effect on bleomycin-induced pulmonary inflammation by inhibiting the infiltration of inflammatory cells and the secretion of inflammatory cytokines IL-6, IL-1alpha, TNF-alpha and IFN-gamma. Bleomycin 70-79 interleukin 6 Homo sapiens 208-212 7682247-2 1993 The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE). Bleomycin 89-98 interleukin 6 Homo sapiens 15-32 7682247-2 1993 The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE). Bleomycin 89-98 interleukin 6 Homo sapiens 34-37 7682247-3 1993 Heat (45 degrees C, 10 min) and exposure to 1 micrograms/ml bleomycin for 1 h at 37 degrees C induced similar levels of HSF binding in all four cell lines. Bleomycin 60-69 interleukin 6 Homo sapiens 120-123 7682247-4 1993 We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding. Bleomycin 20-29 interleukin 6 Homo sapiens 113-116 7682247-4 1993 We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding. Bleomycin 67-76 interleukin 6 Homo sapiens 113-116 7682247-5 1993 The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin. Bleomycin 98-107 interleukin 6 Homo sapiens 23-26 7682247-6 1993 The amount of activated HSF was directly proportional to the time elapsed since bleomycin treatment. Bleomycin 80-89 interleukin 6 Homo sapiens 24-27 7682247-7 1993 Our results therefore indicate no difference between CHO and its bleomycin-sensitive derivatives in the ability to initiate the heat shock response as determined by the production of activated HSF in response to either heat or bleomycin. Bleomycin 227-236 interleukin 6 Homo sapiens 193-196 29348392-4 2018 The senescence-associated beta-galactosidase activity, the protein expression of P16 and P21, and inflammatory-related marker gene levels IL-1beta, IL-6, and TNF-alpha were increased in bleomycin-treated AFSCs in a dose-dependent manner. Bleomycin 186-195 interleukin 6 Homo sapiens 148-152 29348392-5 2018 Rapamycin treatment decreased the gene expression of MMP-3, MMP-13, IL-1beta, IL-6, TNF-alpha, and protein levels of P16 and P21 in bleomycin-treated AFSCs. Bleomycin 132-141 interleukin 6 Homo sapiens 78-82 23526221-8 2013 We observed significant up-regulation of IL-1beta and IL-6 in bronchoalveolar lavage fluid (BALF) in bleomycin-induced lung fibrosis in vivo. Bleomycin 101-110 interleukin 6 Homo sapiens 54-58 23526221-9 2013 Importantly, primary fibrotic ATII cells isolated from lungs subjected to bleomycin secreted enhanced IL-1beta and IL-6 in vitro. Bleomycin 74-83 interleukin 6 Homo sapiens 115-119 20725963-1 2010 The formation of hypertrophic scars (HSF) is a frequent medical outcome of wound repair and often requires further therapy with treatments such as silicone gel sheets (SGS) or apoptosis-inducing agents, including bleomycin. Bleomycin 213-222 interleukin 6 Homo sapiens 37-40 10090171-8 1999 The cellular release of IL-1beta, TNF-alpha, and IL-6 was elevated in response to bleomycin exposure in both controls and patients with SSc. Bleomycin 82-91 interleukin 6 Homo sapiens 49-53