PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31075901-7 2019 Our data suggest that an increased constitutive JAM-A protein level in P2X7 receptor knockout mice may have a protective effect against bleomycin-induced lung injury. Bleomycin 136-145 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 71-84 31075901-8 2019 Bleomycin-treated precision-cut lung slices from P2X7 receptor knockout mice responded with a lower increase in mRNA expression of JAM-A than bleomycin-treated precision-cut lung slices from wildtype mice. Bleomycin 0-9 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 49-62 31075901-8 2019 Bleomycin-treated precision-cut lung slices from P2X7 receptor knockout mice responded with a lower increase in mRNA expression of JAM-A than bleomycin-treated precision-cut lung slices from wildtype mice. Bleomycin 142-151 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 49-62 24941004-3 2014 In addition, P2X7 receptor-deficient mice show reduced inflammation and lung fibrosis after exposure with bleomycin. Bleomycin 106-115 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 13-26 24941004-7 2014 Additional in vitro experiments with bleomycin treated precision cut lung slices showed a greater sensitivity of the P2X7 receptor knockout mice in terms of aquaporin-5 reduction as wild type animals. Bleomycin 37-46 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 117-130 24941004-8 2014 Finally, P2X7 receptor function was examined by using the alveolar epithelial cell lines E10 and MLE-12 for stimulation experiments with bleomycin. Bleomycin 137-146 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 9-22 22192844-0 2012 Activation of P2X7R and downstream effects in bleomycin treated lung epithelial cells. Bleomycin 46-55 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 14-19