PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31392398-8 2019 Multiple genes related to chemotaxis, IL-1, chemokines, regulation of inflammation, and extracellular signal-regulated kinases (ERK) were upregulated in lungs of mice treated with bleomycin and MIA-602. Bleomycin 180-189 interleukin 1 complex Mus musculus 38-42 28678919-6 2017 As a result, cell viability was significantly decreased, as well as apoptosis and the expression of IL-1 and TNF-alpha were remarkably increased after 50 and 100 mug/mL of bleomycin administration. Bleomycin 172-181 interleukin 1 complex Mus musculus 100-104 2426952-13 1986 In contrast, bleomycin treatment caused a reduction in alveolar macrophage interleukin-1 (IL-1) production, and NDGA treatment did not alter this reduction, which suggests that MDGF is separate from IL-1 in this case, and that MDGF played a more dominant role, at least in this model of pulmonary fibrosis. Bleomycin 13-22 interleukin 1 complex Mus musculus 90-94 17992263-6 2007 Exogenous rIL-1beta recapitulated a high degree of bleomycin-induced lung pathology, and specific blockade of IL-1R1 by IL-1 receptor antagonist dramatically reduced bleomycin-induced inflammation. Bleomycin 51-60 interleukin 1 complex Mus musculus 11-15 17992263-8 2007 In conclusion, bleomycin-induced lung pathology required the inflammasome and IL-1R1/MyD88 signaling, and IL-1 represented a critical effector of pathology and therapeutic target of chronic lung inflammation and fibrosis. Bleomycin 15-24 interleukin 1 complex Mus musculus 78-82 17569781-7 2007 Therefore, MSCs protect lung tissue from BLM-induced injury by blocking TNF-alpha and IL-1, two fundamental proinflammatory cytokines in lung. Bleomycin 41-44 interleukin 1 complex Mus musculus 86-90