PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10612569-1 1999 OBJECTIVE: We previously observed increased expression of interleukin-1beta, platelet-derived growth factor-A, and insulin-like growth factor-I in bronchoalveolar lavage (BAL) cells during the development of pulmonary fibrosis after an intraperitoneal administration of bleomycin in mice. Bleomycin 270-279 insulin-like growth factor 1 Mus musculus 94-143 8617091-0 1996 Increased expression of platelet-derived growth factor A and insulin-like growth factor-I in BAL cells during the development of bleomycin-induced pulmonary fibrosis in mice. Bleomycin 129-138 insulin-like growth factor 1 Mus musculus 61-89 32269725-0 2020 Metformin ameliorates bleomycin-induced pulmonary fibrosis in mice by suppressing IGF-1. Bleomycin 22-31 insulin-like growth factor 1 Mus musculus 82-87 32269725-7 2020 Our study showed that intratracheal injection of bleomycin induced pulmonary fibrosis in mice, with observed elevation in collagen, fibronectin and alpha-SMA level, characterized by the enhanced IGF-1 and PI3K expression. Bleomycin 49-58 insulin-like growth factor 1 Mus musculus 195-200 32269725-9 2020 Our results show that metformin attenuates bleomycin-induced pulmonary fibrosis via IGF-1 pathway. Bleomycin 43-52 insulin-like growth factor 1 Mus musculus 84-89 23987664-8 2013 The relevance of the IGF-1 pathway in this model was then demonstrated by showing lung tissue of bleomycin treated C57BL/6J mice had increased expression of Igf1 and that increased numbers of Igf-1 positive cells, predominantly in macrophages, were detected in the lungs. Bleomycin 97-106 insulin-like growth factor 1 Mus musculus 21-26 30121056-0 2018 Octreotide ameliorates dermal fibrosis in bleomycin-induced scleroderma Background/aim: Insulin-like growth factor (IGF)-I is a differentiation and growth factor. Bleomycin 42-51 insulin-like growth factor 1 Mus musculus 88-122 23987664-8 2013 The relevance of the IGF-1 pathway in this model was then demonstrated by showing lung tissue of bleomycin treated C57BL/6J mice had increased expression of Igf1 and that increased numbers of Igf-1 positive cells, predominantly in macrophages, were detected in the lungs. Bleomycin 97-106 insulin-like growth factor 1 Mus musculus 157-161 23987664-8 2013 The relevance of the IGF-1 pathway in this model was then demonstrated by showing lung tissue of bleomycin treated C57BL/6J mice had increased expression of Igf1 and that increased numbers of Igf-1 positive cells, predominantly in macrophages, were detected in the lungs. Bleomycin 97-106 insulin-like growth factor 1 Mus musculus 192-197 22493012-2 2012 We previously demonstrated that treatment of mice with IGF-1 receptor-blocking antibody (A12) improved early survival in bleomycin-induced lung injury. Bleomycin 121-130 insulin-like growth factor 1 Mus musculus 55-60