PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8635193-0	1995	Restoration of interleukin-2 production in tumor-bearing rats through reducing tumor-derived transforming growth factor beta by treatment with bleomycin.	Bleomycin	143-152	interleukin 2	Rattus norvegicus	15-28	
8635193-7	1995	In vitro experiments also showed that TGF beta activity, mRNA expression, and protein synthesis in KDH-8 tumor cells were reduced by bleomycin treatment, and that bleomycin-treated-KDH-8-tumor-cell-conditioned medium did not inhibit IL-2 production from normal rat splenocytes.	Bleomycin	133-142	interleukin 2	Rattus norvegicus	233-237	
8635193-7	1995	In vitro experiments also showed that TGF beta activity, mRNA expression, and protein synthesis in KDH-8 tumor cells were reduced by bleomycin treatment, and that bleomycin-treated-KDH-8-tumor-cell-conditioned medium did not inhibit IL-2 production from normal rat splenocytes.	Bleomycin	163-172	interleukin 2	Rattus norvegicus	233-237	
8635193-8	1995	These results suggest that bleomycin treatment restored IL-2 production in tumor-bearing rats through reducing the tumor-derived TGF beta.	Bleomycin	27-36	interleukin 2	Rattus norvegicus	56-60	
7683934-5	1993	Administration of BLM, 5 mg/kg, on day 8, restored IL-2 and IL-6 production and significantly increased TNF production by day 14 of tumor burden as compared with the amounts of cytokine produced by the mitogen-stimulated untreated tumor-bearing rat spleen cells.	Bleomycin	18-21	interleukin 2	Rattus norvegicus	51-55	
2429940-0	1986	Potentiation of release of interleukin-2 by bleomycin.	Bleomycin	44-53	interleukin 2	Rattus norvegicus	27-40	
2445487-0	1987	Enhancement of interleukin-2 release in rats by treatment with bleomycin and adriamycin in vivo.	Bleomycin	63-72	interleukin 2	Rattus norvegicus	15-28	
2445487-1	1987	Spleen cells from rats previously injected with bleomycin (10 mg/kg) or Adriamycin (1 mg/kg) were able to release higher levels of interleukin-2 (IL-2) than cells from untreated animals.	Bleomycin	48-57	interleukin 2	Rattus norvegicus	131-144	
2445487-1	1987	Spleen cells from rats previously injected with bleomycin (10 mg/kg) or Adriamycin (1 mg/kg) were able to release higher levels of interleukin-2 (IL-2) than cells from untreated animals.	Bleomycin	48-57	interleukin 2	Rattus norvegicus	146-150	
2429940-1	1986	The antineoplastic drug bleomycin, which has not been shown to have immunosuppressive activity, was tested for its effect on concanavalin A-induced interleukin-2 production.	Bleomycin	24-33	interleukin 2	Rattus norvegicus	148-161	
2429940-3	1986	However, using a suboptimal dose of concanavalin A, bleomycin increased interleukin-2 release significantly.	Bleomycin	52-61	interleukin 2	Rattus norvegicus	72-85	
2429940-7	1986	It is suggested that bleomycin, and probably other cytotoxic drugs, may modulate the immune response through its effects on the release of immunostimulating cytokines such as interleukin-1 and -2.	Bleomycin	21-30	interleukin 2	Rattus norvegicus	175-195