PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29556240-11 2018 The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs. SC 26196 20-27 fatty acid desaturase 2 Homo sapiens 4-9 35560527-4 2022 The EAC cell line FLO-1 was treated with FADS2 selective inhibitor SC26196, and/or bile acid cocktail, followed by immunofluorescence staining for gammaH2AX. SC 26196 67-74 fatty acid desaturase 2 Homo sapiens 41-46 35560527-10 2022 Finally, the FADS2 selective inhibitor SC26196 significantly reduced polyunsaturated lipids with three and four double bonds and reduced bile acid-induced DNA double-strand breaks in FLO-1 cells in vitro. SC 26196 39-46 fatty acid desaturase 2 Homo sapiens 13-18 20086206-5 2010 SC-26196 and sterculic acid specifically inhibit the Delta6D and Delta9D activities with an IC(50) value of 0.1 microM and 0.9 microM, respectively. SC 26196 0-8 fatty acid desaturase 2 Homo sapiens 53-60 12848296-0 2003 Effect of the delta6-desaturase inhibitor SC-26196 on PUFA metabolism in human cells. SC 26196 42-50 fatty acid desaturase 2 Homo sapiens 14-31