PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2000226-1	1991	By selective oligonucleotide hybridization of polymerase chain reaction (PCR) amplified tumor DNAs we have analysed the incidence of mutations at codon 61 of the Ha-ras gene in 42 liver tumors spontaneously developed in Balb/c, C3Hf and B6C3 male mice, and in 79 liver tumors induced by the chemical carcinogens diethylnitrosamine (NDEA) and urethan in B6C3 and B6C male and female mice.	Urethane	342-349	Harvey rat sarcoma virus oncogene	Mus musculus	162-168	
18560355-3	2008	Herein, we examined urethane-induced lung tumorigenesis in a new mouse model developed by replacing the Kras gene with an Hras gene in the susceptible A/J-type Pas1 locus and crossing these mice with either C57BL/6J or A/J mice.	Urethane	20-28	Harvey rat sarcoma virus oncogene	Mus musculus	122-126	
10767618-11	2000	In tumors induced by urethane in mice, codon 61 of the Ha-ras gene (liver, skin) and of the Ki-ras gene (lung) seems to be a characteristic target.	Urethane	21-29	Harvey rat sarcoma virus oncogene	Mus musculus	55-61	
1352887-5	1992	Activated Ha-ras genes with 61st codon A----T mutations were found in the epidermis of mice 1 week after topical initiation with 7,12-dimethylbenz[a]anthracene or urethane by using this assay.	Urethane	163-171	Harvey rat sarcoma virus oncogene	Mus musculus	10-16	
10779650-0	2000	Carcinogen dose-dependent variation in the transgene mutation spectrum in urethane-induced lung tumors in transgenic mice carrying the human prototype c-Ha-ras gene.	Urethane	74-82	Harvey rat sarcoma virus oncogene	Mus musculus	151-159	
2000226-2	1991	The incidence of Ha-ras gene mutations in both spontaneously developed and urethan-induced liver tumors was 50%-63% in mice genetically susceptible to hepatocarcinogenesis (C3Hf, B6C3) and 7%-9% in mice genetically resistant (Balb/c, B6C).	Urethane	75-82	Harvey rat sarcoma virus oncogene	Mus musculus	17-23	
2000226-6	1991	Our results indicate that liver tumors induced by NDEA or urethan or spontaneously arisen have a different pattern of Ha-ras mutations at codon 61 and that these mutations constitute a rare molecular alteration in the pathogenesis of liver tumors in genetically resistant mice.	Urethane	58-65	Harvey rat sarcoma virus oncogene	Mus musculus	118-124	
2567173-0	1989	Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.	Urethane	79-87	Harvey rat sarcoma virus oncogene	Mus musculus	27-37	
2567173-7	1989	The results demonstrate a highly consistent activation of the Ha-ras oncogene by a specific point mutation, suggesting a functional role for an activated ras gene in the initiation of mouse skin tumors by urethane.	Urethane	205-213	Harvey rat sarcoma virus oncogene	Mus musculus	62-68