PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26616205-8 2016 Among seven xanthine derivatives tested at 50-300muM, caffeine, theobromine and acefylline proved to be the most potent enhancers of in vitro deimination of FLG by PAD1 and PAD3. Theobromine 64-75 filaggrin Homo sapiens 157-160