PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1302044-5	1992	The most striking finding was that CYP2E1 (the ethanol-inducible form) had major influences upon caffeine metabolism: in particular, it catalysed the formation of theophylline and theobromine from caffeine.	Theobromine	180-191	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	35-41	
10215755-7	1999	Consistent with the microsomal studies, recombinant CYP1A2 and CYP2E1 exhibited similar apparent Km values for 7-MX formation and CYP2E1 was further shown to have the capacity to convert TB to both 3-MX and 3,7-DMU.	Theobromine	187-189	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	63-69	
10215755-7	1999	Consistent with the microsomal studies, recombinant CYP1A2 and CYP2E1 exhibited similar apparent Km values for 7-MX formation and CYP2E1 was further shown to have the capacity to convert TB to both 3-MX and 3,7-DMU.	Theobromine	187-189	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	130-136	
1302044-0	1992	Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.	Theobromine	45-56	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	109-115