PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23474268-5	2013	The MyD88-dependent pathway leads to activation of transcription factors, which in turn induce synthesis of inflammatory mediators such as eicosanoids, cytokines and chemokines.	Eicosanoids	139-150	myeloid differentiation primary response gene 88	Mus musculus	4-9	
20643646-3	2010	A comparison of peritoneal macrophages from wild type and knock-out mice demonstrates that the beta-glucan receptor Dectin-1 and MyD88 regulate early release of AA and eicosanoids in response to C. albicans.	Eicosanoids	168-179	myeloid differentiation primary response gene 88	Mus musculus	129-134	
20643646-4	2010	However, cyclooxygenase 2 (COX2) expression and later phase eicosanoid production are defective in MyD88(-/-) but not Dectin-1(-/-) macrophages.	Eicosanoids	60-70	myeloid differentiation primary response gene 88	Mus musculus	99-104	
20643646-10	2010	The results demonstrate that C. albicans engages both beta-glucan and mannan-binding receptors on macrophages that act with MyD88 to regulate the activation of cPLA(2)alpha and eicosanoid production.	Eicosanoids	177-187	myeloid differentiation primary response gene 88	Mus musculus	124-129	
17369491-4	2007	In the present study, we have used gene knockout mice to define an essential role for MyD88 and cytosolic PLA(2)alpha in TLR2-dependent eicosanoid generation.	Eicosanoids	136-146	myeloid differentiation primary response gene 88	Mus musculus	86-91	
17369491-6	2007	These findings provide the first dissection of the mechanisms of TLR-dependent rapid eicosanoid generation, which is MyD88-dependent, requires cPLA(2)alpha, and is amplified by group V sPLA(2) through its regulation of the sequential phosphorylation and activation of ERK1/2 and cPLA(2)alpha.	Eicosanoids	85-95	myeloid differentiation primary response gene 88	Mus musculus	117-122