PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9023819-3 1996 If TNF alpha was abnormally increased in preeclamptic placentas, it might contribute to the increased oxidative stress and the formation of lipid peroxides. Lipid Peroxides 140-155 tumor necrosis factor Homo sapiens 3-12 9023819-9 1996 (3) TNF alpha concentrations in the incubation medium were positively correlated with lipid peroxide concentrations, r = 0.608. Lipid Peroxides 86-100 tumor necrosis factor Homo sapiens 4-13 23487396-7 2011 LPO levels correlated directly with IL-1beta, TNF-alpha, IL-6 and IL-10. Lipid Peroxides 0-3 tumor necrosis factor Homo sapiens 46-55 24216294-8 2014 The study observed a significant positive correlation of lipid peroxides with TNF-alpha levels and the TNF-alpha/IFN-gamma ratio in severe dengue cases. Lipid Peroxides 57-72 tumor necrosis factor Homo sapiens 78-87 8936560-5 1996 The level of lipid peroxide in mice 4 hr after administration of recombinant human TNF and lead acetate (50 mg/kg, intravenously) was markedly higher than that in the mice treated with recombinant human TNF alone. Lipid Peroxides 13-27 tumor necrosis factor Homo sapiens 83-86 8936560-6 1996 By contrast, injection of polymyxin-B (20 mg/kg, intraperitoneally, an anti-endotoxin drug) markedly decreased the lipid peroxide level in the liver of the mice treated with recombinant human TNF and lead acetate. Lipid Peroxides 115-129 tumor necrosis factor Homo sapiens 192-195 8801863-6 1995 Moreover, treatment with TNF resulted in an increase in the ratio of oxidized to reduced glutathione, intracellular free calcium, albumin transfer across endothelial monolayers and lipid hydroperoxides. Lipid Peroxides 181-201 tumor necrosis factor Homo sapiens 25-28 28811499-7 2017 Stress-induction at the onset/progression of this disease is noticed as the high-level of lipid peroxides/low-level of free-thiols in association with increase of inflammatory-markers c-reactive protein and TNF-alpha. Lipid Peroxides 90-105 tumor necrosis factor Homo sapiens 207-216 22433871-7 2012 Glutathione peroxidase-4 (GPx4), which specifically metabolizes lipid hydroperoxides, fell in TNFalpha-stimulated cells prior to death. Lipid Peroxides 64-84 tumor necrosis factor Homo sapiens 94-102 20339360-11 2010 LOOH levels were negatively related to FFM% (R = -0.413, P < 0.05) and positively to FM%, IL-15, TNF-alpha, insulin, total cholesterol, low-density lipoprotein cholesterol, and triglycerides (R = 0.408, R = 0.502, R = 0.341, R = 0.412, R = 0.4036, R = 0.405, R = 0.405, respectively, P < 0.05). Lipid Peroxides 0-4 tumor necrosis factor Homo sapiens 100-109 12588293-0 2003 Intracellular glutathione and lipid peroxide availability and the secretion of vasoactive substances by human umbilical vein endothelial cells after incubation with TNF-alpha. Lipid Peroxides 30-44 tumor necrosis factor Homo sapiens 165-174 15581626-4 2004 Those ROS and lipid peroxides were both involved in TNFalpha-induced apoptosis, whereas only ROS elevation triggered sustained JNK activation. Lipid Peroxides 14-29 tumor necrosis factor Homo sapiens 52-60 16910777-7 2006 The lipid hydroperoxide scavengers, beta-hydroxytoluene and trolox, and the iron chelator, desferroxamine, showed partial recovery of TNF-induced apoptosis. Lipid Peroxides 4-23 tumor necrosis factor Homo sapiens 134-137 15122056-12 2004 RANTES levels negatively correlated with Cu/Zn SOD (p < 0.0001).TNF-alpha positively correlated with age (p < 0.05), total lipid peroxide (p = 0.010), MCP-1 (p < 0.01) and MIP-1beta levels (p < 0.01). Lipid Peroxides 129-143 tumor necrosis factor Homo sapiens 67-76 11597127-1 2001 Treatment of U937 cells with nontoxic concentrations of TNFalpha increased the DNA strand scission induced by a short-chain lipid hydroperoxide analogue, tert-butylhydroperoxide. Lipid Peroxides 124-143 tumor necrosis factor Homo sapiens 56-64 11228746-3 1999 TNF-induced NF-kappa B activation was inhibited by both superoxide and lipid peroxide quenchers but potentiated by an hydroxyl radical quencher. Lipid Peroxides 71-85 tumor necrosis factor Homo sapiens 0-3 11228746-7 1999 TNF cytotoxicity, however, was potentiated by superoxide radical quenchers and suppressed by hydroxyl radical and lipid peroxide quenchers. Lipid Peroxides 114-128 tumor necrosis factor Homo sapiens 0-3 11228746-8 1999 Overall, these results suggest that hydroxyl radicals mediate TNF-induced apoptosis but not activation of NF-kappa B, AP-1, and JNK; superoxide radicals mediate NF-kappa B and JNK activation but potentiate apoptosis; and lipid peroxides are required for all the signals induced by TNF. Lipid Peroxides 221-236 tumor necrosis factor Homo sapiens 62-65