PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9643019-5 1998 METHODS: (1) Lipid peroxides were formed by incubation of linoleic acid with lipoxygenase from soybean, separated by thin layer chromatography and incubated with tetramethylbenzidine. Lipid Peroxides 13-28 linoleate 9S-lipoxygenase-4 Glycine max 77-89 3122826-5 1987 Lipoxygenase catalyzes the oxidation of NDGA by LOOH at a rate that is consistent with the independently determined rate constant for the reduction of Eox by NDGA. Lipid Peroxides 48-52 linoleate 9S-lipoxygenase-4 Glycine max 0-12 3122826-7 1987 Because the catalytically inactive Ered is oxidized by fatty acid hydroperoxides (e.g., LOOH) to give the active Eox, reducing agents such as NDGA are most effective as lipoxygenase inhibitors at low hydroperoxide concentrations. Lipid Peroxides 55-80 linoleate 9S-lipoxygenase-4 Glycine max 169-181 3122826-7 1987 Because the catalytically inactive Ered is oxidized by fatty acid hydroperoxides (e.g., LOOH) to give the active Eox, reducing agents such as NDGA are most effective as lipoxygenase inhibitors at low hydroperoxide concentrations. Lipid Peroxides 88-92 linoleate 9S-lipoxygenase-4 Glycine max 169-181 3122826-8 1987 Our results suggest that in vivo, where lipid hydroperoxides are maintained at low steady-state levels, reduction of lipoxygenase from the ferric to ferrous state may be important in the regulation of lipoxygenase activity and hence leukotriene biosynthesis. Lipid Peroxides 40-60 linoleate 9S-lipoxygenase-4 Glycine max 117-129 9643019-11 1998 (2) In the isolated retinae of pigs lipid peroxides became visible as electron-dense structures in the rod outer segments (ROS) after treatment with lipoxygenase and were lacking in the other parts of the retina. Lipid Peroxides 36-51 linoleate 9S-lipoxygenase-4 Glycine max 149-161 9643019-12 1998 Without treatment with lipoxygenase lipid peroxides were only infrequently seen in ROS. Lipid Peroxides 36-51 linoleate 9S-lipoxygenase-4 Glycine max 23-35 3138991-5 1988 The data clearly indicate, for the first time, that H2O2 can efficiently replace fatty acid hydroperoxide in a xenobiotic oxidation reaction medicated by the hydroperoxidase activity of lipoxygenase. Lipid Peroxides 81-105 linoleate 9S-lipoxygenase-4 Glycine max 186-198 3101541-0 1986 Determination of stereochemistry in the fatty acid hydroperoxide products of lipoxygenase catalysis. Lipid Peroxides 40-64 linoleate 9S-lipoxygenase-4 Glycine max 77-89 9643019-6 1998 (2) Lipid peroxides were formed by incubation of porcine retinae with soybean lipoxygenase in an oxygensaturated atmosphere. Lipid Peroxides 4-19 linoleate 9S-lipoxygenase-4 Glycine max 78-90 7918597-11 1994 These results strongly suggest that lipoxygenase not only generates lipid hydroperoxides but can also generate superoxide via oxidation of pyridine nucleotides and may, therefore, significantly contribute to oxidative stress in cells. Lipid Peroxides 68-88 linoleate 9S-lipoxygenase-4 Glycine max 36-48 8679548-0 1996 Role of lipid hydroperoxides in the activation of 15-lipoxygenase. Lipid Peroxides 8-28 linoleate 9S-lipoxygenase-4 Glycine max 53-65 8769897-2 1996 Linoleic acid (LA) and its hydroperoxide 13-L-hydroperoxylinoleic acid (LOOH) prepared with soybean lipoxygenase inhibited the response of GABARs in the presence of GABA at high concentrations. Lipid Peroxides 72-76 linoleate 9S-lipoxygenase-4 Glycine max 100-112 1903070-7 1991 The results obtained in this paper for the cooxidation process of hemin and hemoglobin by lipoxygenase can be rationalized in terms of hemin binding at or near to the catalytic center, resulting in a lesser binding of linoleic acid and an enhanced release of radicals, and pigment bleaching by radicals and lipid hydroperoxides. Lipid Peroxides 307-327 linoleate 9S-lipoxygenase-4 Glycine max 90-102 1510955-0 1992 Effect of lipid hydroperoxide on lipoxygenase kinetics. Lipid Peroxides 10-29 linoleate 9S-lipoxygenase-4 Glycine max 33-45