PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23711848-0	2013	Effect of formoterol on eosinophil trans-basement membrane migration induced by interleukin-8-stimulated neutrophils.	Formoterol Fumarate	10-20	C-X-C motif chemokine ligand 8	Homo sapiens	80-93	
24998372-4	2014	RESULTS: Treatment with formoterol and budesonide 72 h before and after RV14 infection reduced RV14 titers and cytokine concentrations, including interleukin (IL)-1beta, IL-6 and IL-8, in supernatants and viral RNA within cells.	Formoterol Fumarate	24-34	C-X-C motif chemokine ligand 8	Homo sapiens	179-183	
23711848-3	2013	In this study, we investigated whether formoterol modified the trans-basement membrane migration (TBM) of eosinophils stimulated with neutrophils and IL-8.	Formoterol Fumarate	39-49	C-X-C motif chemokine ligand 8	Homo sapiens	150-154	
23711848-11	2013	However, formoterol modestly but significantly attenuated the TBM of eosinophils stimulated with neutrophils and IL-8.	Formoterol Fumarate	9-19	C-X-C motif chemokine ligand 8	Homo sapiens	113-117	
23573194-8	2013	Budesonide with Formoterol reduced IL-17A and RORgamma(t), while increased FOXP3 in cultured T-lymphocytes from mild-moderate asthma/persistent rhinitis, and reduced the IL-8 release mediated by IL-17A present in NW and Ss from mild-moderate asthma/persistent rhinitis in nasal and bronchial epithelial cells.	Formoterol Fumarate	16-26	C-X-C motif chemokine ligand 8	Homo sapiens	170-174	
19926732-6	2010	Formoterol and salmeterol inhibited LPS-stimulated release of TNF-alpha (mean effective concentration (EC(50)) 2.4+/-1.8 and 3.5+/-2.7 nM, respectively; n = 11-16), GM-CSF (EC(50) 24.6+/-2.1 and 52.4+/-40.8 nM, respectively, n = 11-12) but not CXCL8 from LPS-stimulated MDM.	Formoterol Fumarate	0-10	C-X-C motif chemokine ligand 8	Homo sapiens	244-249	
11491146-2	2001	Addition of formoterol (> or = 10(-10) M) reduced granulocyte macrophage-colony stimulating factor (GM-CSF) levels, as assessed by enzyme-linked immunosorbent assay, by 40-50% and increased interleukin (IL)-8 levels by approximately 50%.	Formoterol Fumarate	12-22	C-X-C motif chemokine ligand 8	Homo sapiens	193-211	
20423350-5	2010	KEY RESULTS: Pre-incubation with beta(2)-adrenoceptor agonists (salbutamol, salmeterol, formoterol) augmented the release and mRNA expression of IL-6 and IL-8 induced by IL-1beta and IL-1beta plus histamine, whereas NF-kappaB-dependent transcription was significantly repressed, and AP-1-dependent transcription was unaffected.	Formoterol Fumarate	88-98	C-X-C motif chemokine ligand 8	Homo sapiens	154-158	
18415826-0	2008	Effect of budesonide and formoterol on IL-6 and IL-8 release from primary bronchial epithelial cells.	Formoterol Fumarate	25-35	C-X-C motif chemokine ligand 8	Homo sapiens	48-52	
16236838-7	2005	RESULTS: Formoterol therapy significantly reduced sputum IL-8 levels and neutrophil numbers compared to placebo.	Formoterol Fumarate	9-19	C-X-C motif chemokine ligand 8	Homo sapiens	57-61	
16236838-8	2005	There was a significant correlation between the reduction in sputum IL-8 levels and the number of neutrophils, indicating that formoterol may attenuate neutrophilic airway inflammation by inhibiting IL-8 production.	Formoterol Fumarate	127-137	C-X-C motif chemokine ligand 8	Homo sapiens	68-72	
16236838-8	2005	There was a significant correlation between the reduction in sputum IL-8 levels and the number of neutrophils, indicating that formoterol may attenuate neutrophilic airway inflammation by inhibiting IL-8 production.	Formoterol Fumarate	127-137	C-X-C motif chemokine ligand 8	Homo sapiens	199-203	
17932597-4	2007	METHODS: The effects of the LABAs salmeterol and formoterol on the synthesis of soluble interleukin-8 (IL-8), granulocyte-macrophage colony-stimulating factor (GM-CSF), and vascular endothelial growth factor (VEGF) in the human airway epithelial cell line A549 was investigated in vitro.	Formoterol Fumarate	49-59	C-X-C motif chemokine ligand 8	Homo sapiens	88-101	
17932597-6	2007	RESULTS: Both salmeterol and formoterol significantly suppressed IL-8, GM-CSF, and VEGF secretion from tumor necrosis factor-alpha-stimulated A549 cells.	Formoterol Fumarate	29-39	C-X-C motif chemokine ligand 8	Homo sapiens	65-69	
17932597-7	2007	Results indicated that formoterol was more potent than salmeterol in suppressing IL-8 and VEGF production.	Formoterol Fumarate	23-33	C-X-C motif chemokine ligand 8	Homo sapiens	81-85	
15679717-4	2005	RESULTS: The release of GM-CSF, RANTES and IL-8 in ISC was significantly reduced by BDP plus salbutamol or formoterol as compared with either drug alone (P < 0.0001).	Formoterol Fumarate	107-117	C-X-C motif chemokine ligand 8	Homo sapiens	43-47	
11491146-9	2001	In conclusion, the combination of budesonide and formoterol reduces the secretion of granulocyte macrophage-colony stimulating factor to basal levels and counteracts the capacity of formoterol alone to induce interleukin-8 production, modulations which may facilitate improved asthma control.	Formoterol Fumarate	49-59	C-X-C motif chemokine ligand 8	Homo sapiens	209-222	
11491146-9	2001	In conclusion, the combination of budesonide and formoterol reduces the secretion of granulocyte macrophage-colony stimulating factor to basal levels and counteracts the capacity of formoterol alone to induce interleukin-8 production, modulations which may facilitate improved asthma control.	Formoterol Fumarate	182-192	C-X-C motif chemokine ligand 8	Homo sapiens	209-222