PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19673610-7	2009	Rasagiline increases the protein and mRNA levels of GDNF in dopaminergic SH-SY5Y cells, whereas (-)deprenyl increases those of BDNF.	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	52-56	
23739004-5	2013	Rasagiline and selegiline preferentially increase GDNF and BDNF in nonhuman primates and Parkinsonian patients, respectively.	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	50-54	
22892822-8	2013	Rasagiline and (-)deprenyl induced preferentially GDNF and BDNF in cellular and non-human primate experiments, and (-)deprenyl increased BDNF level in the cerebrospinal fluid of parkinsonian patients.	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	50-54	
20698822-7	2010	In cellular models, selegiline and rasagiline increased the different neurotrophic factors classes, neurotrophins (nerve growth factor, brain-derive neurotrophic factor, neurotrophin 3) and ligands of glial cell line-derived neurotrophic factor, respectively.	rasagiline	35-45	glial cell derived neurotrophic factor	Homo sapiens	201-244	
28577058-9	2017	Rasagiline increased BDNF and GDNF, which Mao-B and Mao-A knockdown inhibited.	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	30-34	
18077571-0	2007	Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy.	rasagiline	103-113	glial cell derived neurotrophic factor	Homo sapiens	34-38	
18077571-5	2007	We have recently reported that the anti-PD drug rasagiline, the anti-AD drug ladostigil, and their propargyl moiety, propargylamine, enhanced the expression levels of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor, endogenous NTFs associated with activation of phosphatidylinositol 3-kinase, protein kinase, and mitogen-activated protein kinase cell signaling/survival pathways.	rasagiline	48-58	glial cell derived neurotrophic factor	Homo sapiens	205-248	
17982885-5	2007	At the same time, rasagiline induces anti-apoptotic pro-survival proteins, Bcl-2 and glial cell-line derived neurotrophic factor, which is mediated by activated ERK-NF-kappaB signal pathway.	rasagiline	18-28	glial cell derived neurotrophic factor	Homo sapiens	85-128	
17055733-1	2007	The anti-Parkinson monoamine oxidase (MAO)-B inhibitor rasagiline (Azilect) was shown to possess neuroprotective activities, involving the induction of brain-derived- and glial cell line-derived neurotrophic factors (BDNF, GDNF).	rasagiline	55-65	glial cell derived neurotrophic factor	Homo sapiens	223-227	
17055733-1	2007	The anti-Parkinson monoamine oxidase (MAO)-B inhibitor rasagiline (Azilect) was shown to possess neuroprotective activities, involving the induction of brain-derived- and glial cell line-derived neurotrophic factors (BDNF, GDNF).	rasagiline	67-74	glial cell derived neurotrophic factor	Homo sapiens	223-227	
17447417-10	2006	Rasagiline and other MAO-B inhibitors prevent the activation of apoptotic cascade and induce prosurvival genes, such as bcl-2 and glial cell line-derived neurotrophic factor, in MAO-A-containing cells.	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	130-173	
14687604-1	2004	N-Propargyl-l(R)-aminoindan, rasagiline, an anti-Parkinson drug, was found to increase the protein and mRNA levels of glial cell line-derived neurotrophic factor (GDNF) in human neuroblastoma SH-SY5Y cells, whereas an analogue without a propargyl residue, aminoindan, did not.	rasagiline	29-39	glial cell derived neurotrophic factor	Homo sapiens	118-161	
14687604-1	2004	N-Propargyl-l(R)-aminoindan, rasagiline, an anti-Parkinson drug, was found to increase the protein and mRNA levels of glial cell line-derived neurotrophic factor (GDNF) in human neuroblastoma SH-SY5Y cells, whereas an analogue without a propargyl residue, aminoindan, did not.	rasagiline	29-39	glial cell derived neurotrophic factor	Homo sapiens	163-167	
14687604-6	2004	Sulfasalazine, an inhibitor of IkappaB kinase, suppressed the activation of NF-kappaB and the increase of GDNF by rasagiline simultaneously, further indicating the involvement of the IkappaB kinase-NF-kappaB pathway.	rasagiline	114-124	glial cell derived neurotrophic factor	Homo sapiens	106-110	
12200198-7	2002	Rasagiline prevented the PT in mitochondria directly and also indirectly through induction of antiapoptotic Bcl-2 and a neurotrophic factor, glial cell line-derived neurotrophic factor (GDNF).	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	141-184	
12200198-7	2002	Rasagiline prevented the PT in mitochondria directly and also indirectly through induction of antiapoptotic Bcl-2 and a neurotrophic factor, glial cell line-derived neurotrophic factor (GDNF).	rasagiline	0-10	glial cell derived neurotrophic factor	Homo sapiens	186-190