PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20002521-3 2010 Rasagiline is primarily metabolized by hepatic cytochrome P-450 to form its major metabolite, 1-(R)-aminoindan, a non-amphetamine, weak reversible MAO-B inhibitor compound. rasagiline 0-10 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 47-63 17296539-7 2006 Rasagiline is almost completely eliminated by oxidative metabolism (catalyzed by cytochrome P-450 [CYP] isozyme 1A2) followed by renal excretion of conjugated parent compound and metabolites. rasagiline 0-10 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 81-115 27060436-2 2016 Rasagiline is metabolized by the cytochrome P450 (CYP) system, and the following three major metabolites with potential neuroprotective activity have been identified: 1-aminoindan (AI), 3-hydroxy-N-propargyl-1-aminoindan (3-OH-PAI) and 3-hydroxy-1-aminoindan (3-OH-AI). rasagiline 0-10 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 33-48 27060436-2 2016 Rasagiline is metabolized by the cytochrome P450 (CYP) system, and the following three major metabolites with potential neuroprotective activity have been identified: 1-aminoindan (AI), 3-hydroxy-N-propargyl-1-aminoindan (3-OH-PAI) and 3-hydroxy-1-aminoindan (3-OH-AI). rasagiline 0-10 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 50-53