PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30510203-6	2018	Gene ontology pathway analysis revealed Sirt3 deletion-mediated downregulation of enzymes in several metabolic pathways, including fatty acid oxidation and tricarboxylic acid cycle.	Tricarboxylic Acids	156-174	sirtuin 3	Mus musculus	40-45	
25948682-5	2015	Permeabilized muscle fibers from HFD-fed SIRT3 knockout (KO) mice showed that tricarboxylic acid cycle substrate-based respiration is decreased while fatty acid-based respiration is increased, reflecting a fuel switch from glucose to fatty acids.	Tricarboxylic Acids	78-96	sirtuin 3	Mus musculus	41-46	
23576753-7	2013	These data show that SIRT3 regulates acetylation on multiple proteins, often at multiple sites, across several metabolic pathways including fatty acid oxidation, ketogenesis, amino acid catabolism, and the urea and tricarboxylic acid cycles, as well as mitochondrial regulatory proteins.	Tricarboxylic Acids	215-233	sirtuin 3	Mus musculus	21-26	
33531400-4	2021	Infection of immortalized and primary murine macrophages resulted in reduced levels of SIRT3 mRNA and protein and perturbation of SIRT3-regulated enzymes in the tricarboxylic acid cycle, electron transport chain, and glycolytic pathway.	Tricarboxylic Acids	161-179	sirtuin 3	Mus musculus	130-135	
32526680-0	2020	Sirt3 is a novel target to treat sepsis induced myocardial dysfunction by acetylated modulation of critical enzymes within cardiac tricarboxylic acid cycle.	Tricarboxylic Acids	131-149	sirtuin 3	Mus musculus	0-5	
32526680-7	2020	Quantitative acetyl-proteomics and cardiac metabolomics analysis revealed that loss of Sirt3 led to hyper-acetylation of critical enzymes within cardiac tricarboxylic acid (TCA) cycle and generation of lactate and NADH, subsequently promotion of cardiac dysfunction after sepsis.	Tricarboxylic Acids	153-171	sirtuin 3	Mus musculus	87-92	
32526680-7	2020	Quantitative acetyl-proteomics and cardiac metabolomics analysis revealed that loss of Sirt3 led to hyper-acetylation of critical enzymes within cardiac tricarboxylic acid (TCA) cycle and generation of lactate and NADH, subsequently promotion of cardiac dysfunction after sepsis.	Tricarboxylic Acids	173-176	sirtuin 3	Mus musculus	87-92