PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30788416-2	2019	We recently showed that upregulation of mechanistic target of rapamycin complex 1 (mTORC1) in a restricted segment of the renal tubule leads to downregulation of the tricarboxylic acid (TCA) cycle enzyme fumarate hydratase, to accumulation of the oncometabolite fumarate, and gradual transformation from benign cysts into cystadenomas and papillary carcinomas.	Tricarboxylic Acids	166-184	CREB regulated transcription coactivator 1	Mus musculus	83-89	
30788416-2	2019	We recently showed that upregulation of mechanistic target of rapamycin complex 1 (mTORC1) in a restricted segment of the renal tubule leads to downregulation of the tricarboxylic acid (TCA) cycle enzyme fumarate hydratase, to accumulation of the oncometabolite fumarate, and gradual transformation from benign cysts into cystadenomas and papillary carcinomas.	Tricarboxylic Acids	186-189	CREB regulated transcription coactivator 1	Mus musculus	83-89	
29635516-5	2018	Significant metabolic reprogramming was found in well-established pathways associated with mTORC1 activation, including redox homeostasis, glutamine/tricarboxylic acid cycle, pentose and nucleotide metabolism.	Tricarboxylic Acids	149-167	CREB regulated transcription coactivator 1	Mus musculus	91-97	
25220053-3	2014	Activation of the mTORC1 pathway has been shown previously to promote the anaplerotic entry of glutamine to the TCA cycle via GDH.	Tricarboxylic Acids	112-115	CREB regulated transcription coactivator 1	Mus musculus	18-24	
32211535-8	2020	Mitochondrial bioenergetics and the production of tricarboxylic acid cycle intermediates were decreased upon inhibition of mTORC1 or AMPK.	Tricarboxylic Acids	50-68	CREB regulated transcription coactivator 1	Mus musculus	123-129	
27876792-6	2016	Using in vivo metabolic imaging, metabolomics and transcriptomics, we show that mTORC1 deletion impairs glucose and lipid oxidation, an effect linked to a defect in tricarboxylic acid (TCA) cycle activity.	Tricarboxylic Acids	165-183	CREB regulated transcription coactivator 1	Mus musculus	80-86	
27876792-6	2016	Using in vivo metabolic imaging, metabolomics and transcriptomics, we show that mTORC1 deletion impairs glucose and lipid oxidation, an effect linked to a defect in tricarboxylic acid (TCA) cycle activity.	Tricarboxylic Acids	185-188	CREB regulated transcription coactivator 1	Mus musculus	80-86