PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35085541-7	2022	Further results indicated that inhibition of IRE1 suppressed H2O2 induced cell senescence, IL-1beta-induced cellular reactive oxygen species (ROS) level and the activation of NF-kappaB, PI3K/Akt and MAPK signaling pathways.	Hydrogen Peroxide	61-65	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	45-49	
33080949-3	2020	Focusing on three ER-localized proteins-the molecular chaperone BiP, the transmembrane stress-sensor IRE1, and the calcium pump SERCA2-we discuss how post-translational modification of protein cysteines by H2O2 can alter ER activities.	Hydrogen Peroxide	206-210	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	101-105	
30987565-14	2019	The expression of CHOP, PERK, IRE1 and ATF6 mRNA was significantly up-regulated in the presence of CCl4 or H2O2 (P < 0.05).	Hydrogen Peroxide	107-111	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	30-34