PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24024170-0	2013	A quantitative study of the cell-type specific modulation of c-Rel by hydrogen peroxide and TNF-alpha.	Hydrogen Peroxide	70-87	REL proto-oncogene, NF-kB subunit	Homo sapiens	61-66	
24024170-7	2013	In MCF-7 cells, H2O2, in the presence of TNF-alpha, tripled the induction of c-Rel triggered either by TNF-alpha or H2O2.	Hydrogen Peroxide	16-20	REL proto-oncogene, NF-kB subunit	Homo sapiens	77-82	
24024170-7	2013	In MCF-7 cells, H2O2, in the presence of TNF-alpha, tripled the induction of c-Rel triggered either by TNF-alpha or H2O2.	Hydrogen Peroxide	116-120	REL proto-oncogene, NF-kB subunit	Homo sapiens	77-82	
24024170-8	2013	Conversely, in HeLa cells, H2O2 had a small antagonistic effect on TNF-alpha-induced c-Rel nuclear levels, concomitantly with a 50 % induction of IkappaB-epsilon, the preferential inhibitor protein of c-Rel dimers.	Hydrogen Peroxide	27-31	REL proto-oncogene, NF-kB subunit	Homo sapiens	85-90	
24024170-8	2013	Conversely, in HeLa cells, H2O2 had a small antagonistic effect on TNF-alpha-induced c-Rel nuclear levels, concomitantly with a 50 % induction of IkappaB-epsilon, the preferential inhibitor protein of c-Rel dimers.	Hydrogen Peroxide	27-31	REL proto-oncogene, NF-kB subunit	Homo sapiens	201-206	
24024170-9	2013	The 6-fold higher c-Rel/IkappaB-epsilon ratio found in MCF-7 cells when compared with HeLa cells, may be a contributing factor for the cell-type dependent modulation of c-Rel by H2O2.	Hydrogen Peroxide	178-182	REL proto-oncogene, NF-kB subunit	Homo sapiens	18-23	
24024170-9	2013	The 6-fold higher c-Rel/IkappaB-epsilon ratio found in MCF-7 cells when compared with HeLa cells, may be a contributing factor for the cell-type dependent modulation of c-Rel by H2O2.	Hydrogen Peroxide	178-182	REL proto-oncogene, NF-kB subunit	Homo sapiens	169-174	
24024170-10	2013	Our results suggest that H2O2 might have an important cell-type specific role in the regulation of c-Rel-dependent processes, e.g. cancer or wound healing.	Hydrogen Peroxide	25-29	REL proto-oncogene, NF-kB subunit	Homo sapiens	99-104	
22580300-10	2012	These protective effects of c-Rel overexpression in H(2)O(2)-induced oxidative stress were significantly reduced after UCP4 knockdown, indicating that UCP4 is a target effector gene of the NF-kappaB c-Rel prosurvival pathway to mitigate the effects of oxidative stress.	Hydrogen Peroxide	52-60	REL proto-oncogene, NF-kB subunit	Homo sapiens	28-33	
22580300-10	2012	These protective effects of c-Rel overexpression in H(2)O(2)-induced oxidative stress were significantly reduced after UCP4 knockdown, indicating that UCP4 is a target effector gene of the NF-kappaB c-Rel prosurvival pathway to mitigate the effects of oxidative stress.	Hydrogen Peroxide	52-60	REL proto-oncogene, NF-kB subunit	Homo sapiens	199-204	
19706790-10	2009	c-Rel protected also against streptozotocin- and H(2)O(2)-induced cell death, in both intact rat islets and human islet cells.	Hydrogen Peroxide	49-57	REL proto-oncogene, NF-kB subunit	Homo sapiens	0-5	
9990295-6	1999	Cell death does correlate with alterations in NF-kappa B activity: the NSAIDs, butyrate and H2O2 enhance c-Rel complex formation by TNF-alpha and provide an overall enhancement of NF-kappa B activation by Fas.	Hydrogen Peroxide	92-96	REL proto-oncogene, NF-kB subunit	Homo sapiens	105-110