PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32409033-6 2020 The prepared sensor showed good performance for H2O2 detection from 6.85 nM to 7 muM with the detection limit of 2.06 nM (S/N = 3), and pH test from 3.0 to 9.0. Hydrogen Peroxide 48-52 latexin Homo sapiens 81-84 1249070-3 1976 In addition, such oxidants as vitamin K5 (50 muM), hydrogen peroxide (4mM), methylene blue (50 muM), and diamide (20 mM) also maximally activated 3-O-methylglucose transport and their effects were not additive to those of maximal concentrations of insulin. Hydrogen Peroxide 51-68 latexin Homo sapiens 95-98 803813-3 1975 The method is capable of assaying hydrogen peroxide concentrations as low as 7 muM. Hydrogen Peroxide 34-51 latexin Homo sapiens 79-82 32456920-2 2020 In this work, porous regular hexagonal-shaped FeS2 nanosheets (NSs) with a side length of about 1 mum are employed as a peroxidase mimic to detect H2O2. Hydrogen Peroxide 147-151 latexin Homo sapiens 98-101 32456920-4 2020 The FeS2 NSs exhibit high sensitivity in linear range of 0.02-4.00 muM of H2O2 with a limit of detection (LOD) of 7.60 nM (S/N = 3). Hydrogen Peroxide 74-78 latexin Homo sapiens 67-70 31967629-10 2020 At lower concentrations (<100 muM), consistent with the enzyme-like activities detected in solution, all three NPs significantly decreased H2O2-induced cytotoxicity in Caco-2 cells. Hydrogen Peroxide 139-143 latexin Homo sapiens 30-33 32607608-7 2020 As a result, the determination of H2O2 without the aid of complicated instruments is achieved in the range 2.0 muM to 0.2 mM with a detection limit of 1.02 muM. Hydrogen Peroxide 34-38 latexin Homo sapiens 111-114 32607608-7 2020 As a result, the determination of H2O2 without the aid of complicated instruments is achieved in the range 2.0 muM to 0.2 mM with a detection limit of 1.02 muM. Hydrogen Peroxide 34-38 latexin Homo sapiens 156-159 32252908-4 2020 A highly efficient, rapid, sensitive, and selective determination of H2O2 and glucose have been achieved with very low detection limits of 22 nM, and 27.6 nM over 0-8 muM and 0-1000 muM linear ranges, respectively. Hydrogen Peroxide 69-73 latexin Homo sapiens 167-170 32252908-4 2020 A highly efficient, rapid, sensitive, and selective determination of H2O2 and glucose have been achieved with very low detection limits of 22 nM, and 27.6 nM over 0-8 muM and 0-1000 muM linear ranges, respectively. Hydrogen Peroxide 69-73 latexin Homo sapiens 182-185 31690112-3 2019 Cell proliferation was increased in low doses of H2O2 (10-4 to 10-2 muM), whereas sublethal concentrations of H2O2 (>200 muM) induced apoptosis. Hydrogen Peroxide 49-53 latexin Homo sapiens 68-71 31845299-7 2019 The fluorescent probe, best operated at excitation/emission wavelengths of 554/577 nm, allows hydrogen peroxide to be determined in concentrations as low as 94 pM with a linear range spanning from 1 nM to 1 muM. Hydrogen Peroxide 94-111 latexin Homo sapiens 207-210 31690112-3 2019 Cell proliferation was increased in low doses of H2O2 (10-4 to 10-2 muM), whereas sublethal concentrations of H2O2 (>200 muM) induced apoptosis. Hydrogen Peroxide 110-114 latexin Homo sapiens 121-124 31147043-4 2019 The obtained biosensor exhibited wide linear ranges (glucose: 0.005-10.95 mM; H2O2: 1-510 muM) and a low detection limits (glucose: 0.39 muM; H2O2: 0.136 muM) in alkaline solution (S/N = 3). Hydrogen Peroxide 78-82 latexin Homo sapiens 90-93 31601055-7 2019 Notably, the most active compound 8 displayed the highest protective effect (50% effective concentration (EC50) = 4.31 muM) against tert-butyl, hydroperoxide-induced, SH-SY5Y neurotoxicity cells, which was much better than the baicalein (EC50 = 24.77 muM) and edaravin (EC50 = 5.62 muM). Hydrogen Peroxide 144-157 latexin Homo sapiens 119-122 31601055-7 2019 Notably, the most active compound 8 displayed the highest protective effect (50% effective concentration (EC50) = 4.31 muM) against tert-butyl, hydroperoxide-induced, SH-SY5Y neurotoxicity cells, which was much better than the baicalein (EC50 = 24.77 muM) and edaravin (EC50 = 5.62 muM). Hydrogen Peroxide 144-157 latexin Homo sapiens 251-254 31601055-7 2019 Notably, the most active compound 8 displayed the highest protective effect (50% effective concentration (EC50) = 4.31 muM) against tert-butyl, hydroperoxide-induced, SH-SY5Y neurotoxicity cells, which was much better than the baicalein (EC50 = 24.77 muM) and edaravin (EC50 = 5.62 muM). Hydrogen Peroxide 144-157 latexin Homo sapiens 251-254 31039858-4 2019 Using the modified electrode for the linear sweep voltammetry (LSV) detection of H2O2, the detection limit and sensitivity were determined to be 4.8 muM (S/N 3) and 0.0262 muA muM-1, respectively. Hydrogen Peroxide 81-85 latexin Homo sapiens 149-152 31368448-3 2019 The resulting flexible sensors exhibit capability in detecting ascorbic acid (AA), hydrogen peroxide (H2O2) and L-Histidine (L-His) with detection limits of 2.94, 4.1 and 5.3 muM, respectively. Hydrogen Peroxide 83-100 latexin Homo sapiens 175-178 31147043-4 2019 The obtained biosensor exhibited wide linear ranges (glucose: 0.005-10.95 mM; H2O2: 1-510 muM) and a low detection limits (glucose: 0.39 muM; H2O2: 0.136 muM) in alkaline solution (S/N = 3). Hydrogen Peroxide 78-82 latexin Homo sapiens 137-140 31147043-4 2019 The obtained biosensor exhibited wide linear ranges (glucose: 0.005-10.95 mM; H2O2: 1-510 muM) and a low detection limits (glucose: 0.39 muM; H2O2: 0.136 muM) in alkaline solution (S/N = 3). Hydrogen Peroxide 78-82 latexin Homo sapiens 137-140 31073567-5 2019 Probe 1 has satisfactory sensitivity to hydrogen peroxide with a low detection limit of 0.14 muM (S/N = 3), attributed to a responding mechanism that leads to the oxidation of phenylboronic acid pinacol ester and thereby releases fluorophore 2. Hydrogen Peroxide 40-57 latexin Homo sapiens 93-96 31422477-5 2019 Figures of merit for detection H2O2 assay include (a) a working voltage of 0.7 V (vs. the reversible hydrogen electrode); (b) a wide linear response range (from 0.01 to 1.7 mM), and (c) a low detection limit (0.1 muM). Hydrogen Peroxide 31-35 latexin Homo sapiens 213-216 31214778-8 2019 The limit of electrochemical detection of H2O2 (at a potential as low as 50 mV) is 1.1 muM which is comparable or better than most analogous methods. Hydrogen Peroxide 42-46 latexin Homo sapiens 87-90 31385065-4 2019 A colorimetric method was developed for the determination of H2O2 that has a 1.75 muM detection limit and a linear response in the 10-5 to 10-4 M concentration range. Hydrogen Peroxide 61-65 latexin Homo sapiens 82-85 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 115-119 latexin Homo sapiens 200-203 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 115-119 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 115-119 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 115-119 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 200-203 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 200-203 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 228-231 30852265-9 2019 Based on the excellent catalytic activity of FePPOPs-SO3H, two visual colorimetric sensors for ultrafast detecting H2O2 and glucose, respectively, were constructed with a wide linear range of 50-1800 muM (for H2O2) and 200-1500 muM (for glucose), as well as a relative lower limit of detection (LOD) [26.70 muM (for H2O2) and 16.38 muM (for glucose)]. Hydrogen Peroxide 209-213 latexin Homo sapiens 228-231 31165952-4 2019 The calibration curves obtained are linear for the current versus AA and H2O2 concentration over the range 50-500 muM and 10-140 muM, respectively. Hydrogen Peroxide 73-77 latexin Homo sapiens 114-117 30976770-4 2019 Moreover, the AgFKZSiW12@PPy-based colorimetric biosensing platform towards H2O2 and ascorbic acid (AA) exhibits limits of detection (LOD) as low as 0.12 muM and 2.7 muM, respectively. Hydrogen Peroxide 76-80 latexin Homo sapiens 154-157 30976770-4 2019 Moreover, the AgFKZSiW12@PPy-based colorimetric biosensing platform towards H2O2 and ascorbic acid (AA) exhibits limits of detection (LOD) as low as 0.12 muM and 2.7 muM, respectively. Hydrogen Peroxide 76-80 latexin Homo sapiens 166-169 30816608-6 2019 Also, co-administration of quercetin (especially at 40 and 80 muM) with hydrogen peroxide restored the toxic effects of hydrogen peroxide on rooster semen parameters such as primary and secondary lipid peroxidative indicators and other evaluated variables. Hydrogen Peroxide 72-89 latexin Homo sapiens 62-65 31165952-4 2019 The calibration curves obtained are linear for the current versus AA and H2O2 concentration over the range 50-500 muM and 10-140 muM, respectively. Hydrogen Peroxide 73-77 latexin Homo sapiens 129-132 31165952-5 2019 And the detection limits for AA and H2O2 are 4.2 muM and 1.9 muM, respectively. Hydrogen Peroxide 36-40 latexin Homo sapiens 49-52 31165952-5 2019 And the detection limits for AA and H2O2 are 4.2 muM and 1.9 muM, respectively. Hydrogen Peroxide 36-40 latexin Homo sapiens 61-64 30820500-6 2019 H2O2 was detected with a detection limit of 0.7 muM over two wide linear ranges (from 3 muM to 1 mM and from 1 mM to 0.1 M) and with high sensitivities (757.4 muA mM-1 cm-2 and 315.4 muA mM-1 cm-2), respectively. Hydrogen Peroxide 0-4 latexin Homo sapiens 48-51 30865189-5 2019 Under the most favorable conditions, the linear range for H2O2 detection was 40 muM to 800 muM and the detection limit was 18.9 muM. Hydrogen Peroxide 58-62 latexin Homo sapiens 80-83 30865189-5 2019 Under the most favorable conditions, the linear range for H2O2 detection was 40 muM to 800 muM and the detection limit was 18.9 muM. Hydrogen Peroxide 58-62 latexin Homo sapiens 91-94 30865189-5 2019 Under the most favorable conditions, the linear range for H2O2 detection was 40 muM to 800 muM and the detection limit was 18.9 muM. Hydrogen Peroxide 58-62 latexin Homo sapiens 91-94 31191867-9 2019 At cellular level compound 4 (1 muM) showed significant protective effects in neuroblastoma SH-SY5Y cell line when treated with hydrogen peroxide (400 muM). Hydrogen Peroxide 128-145 latexin Homo sapiens 32-35 31191867-9 2019 At cellular level compound 4 (1 muM) showed significant protective effects in neuroblastoma SH-SY5Y cell line when treated with hydrogen peroxide (400 muM). Hydrogen Peroxide 128-145 latexin Homo sapiens 151-154 30820500-6 2019 H2O2 was detected with a detection limit of 0.7 muM over two wide linear ranges (from 3 muM to 1 mM and from 1 mM to 0.1 M) and with high sensitivities (757.4 muA mM-1 cm-2 and 315.4 muA mM-1 cm-2), respectively. Hydrogen Peroxide 0-4 latexin Homo sapiens 88-91 30886671-4 2019 We have found that H2O2 in concentration range 10-100 muM increases the rise of [Ca2+]i induced by 5-hydroxytryptamine (5-HT) and carbachol and does not affect the calcium signals of ATP, agonist of type 1 protease-activated receptor SFLLRN, histamine and bradykinin. Hydrogen Peroxide 19-23 latexin Homo sapiens 54-57 30336241-5 2019 The electrocatalytic response of the biosensor was proportional to the hydrogen peroxide concentration in the range of 1 muM to 2.2 mM with a limit of detection and sensitivity of 290 nM and 0.024 muA/muM, respectively. Hydrogen Peroxide 71-88 latexin Homo sapiens 121-124 30336241-5 2019 The electrocatalytic response of the biosensor was proportional to the hydrogen peroxide concentration in the range of 1 muM to 2.2 mM with a limit of detection and sensitivity of 290 nM and 0.024 muA/muM, respectively. Hydrogen Peroxide 71-88 latexin Homo sapiens 201-204 30366526-6 2019 Under optimized conditions, the hemin/RGO-CMF composite exhibit a linear response to H2O2 in the concentration range from 0.06 to 540.6 muM with the lower detection limit of 16 nM. Hydrogen Peroxide 85-89 latexin Homo sapiens 136-139 30721353-6 2019 The detection limits are 8 muM for Fe(III) and 0.6 muM for H2O2. Hydrogen Peroxide 59-63 latexin Homo sapiens 51-54 29458613-5 2018 The sensor based on pompon-like Co9S8 displayed a wide linear response ranged from 1.50 muM to 8.51 mM, a favorable sensitivity of 20.80 muA mM-1 cm-2 and a detection limit of 0.45 muM (signal to noise ratio of 3) for hydrogen peroxide. Hydrogen Peroxide 218-235 latexin Homo sapiens 88-91 30357214-2 2018 These nanostructures demonstrated an enhanced release after exposure to an alternating magnetic field, and a complete release of the encapsulated drug after the synergic effect of low pH (4.5), increased concentration of hydrogen peroxide (50 muM), and increased temperature due to the applied magnetic field. Hydrogen Peroxide 221-238 latexin Homo sapiens 243-246 29982029-7 2018 The Bi2S3@N-G/GC electrode demonstrated a wide concentration range for H2O2, from 10 to 42,960 muM, with a sensitivity of 0.1535 muA muM-1 and an obtained limit of detection of 1.9 muM. Hydrogen Peroxide 71-75 latexin Homo sapiens 95-98 29982029-7 2018 The Bi2S3@N-G/GC electrode demonstrated a wide concentration range for H2O2, from 10 to 42,960 muM, with a sensitivity of 0.1535 muA muM-1 and an obtained limit of detection of 1.9 muM. Hydrogen Peroxide 71-75 latexin Homo sapiens 133-136 30186615-9 2018 Results: Pretreatment with low-dose (1 and 5 muM) CAM for 72 h inhibited H2O2-induced reductions of GPx-1, GR, SOD, CAT and HO-1 activities, and mRNA expressions of GPx-1 and HO-1, and improved the GSH/GSSG ratio. Hydrogen Peroxide 73-77 latexin Homo sapiens 45-48 29987346-4 2018 The response current of the sensor showed a good linear relationship with the concentration of H2O2 in the range of 10-1000 muM (R2 = 0.9916). Hydrogen Peroxide 95-99 latexin Homo sapiens 124-127 30516364-6 2019 The captured sweat droplets present strong electrochemical signals using graphene films as the working electrode and metal pins as the counter electrode arrays assembled on 3D printed holders, at the detection limit of 6 muM for H2O2 sensing. Hydrogen Peroxide 229-233 latexin Homo sapiens 221-224 30442395-4 2018 Moreover, copper microelectrode doped with cobalt has demonstrated good reproducibility and long-run stability as well as sensitivity and selectivity towards determination of hydrogen peroxide (limit of detection-0.2 muM) and d-glucose (limit of detection-2.2 muM). Hydrogen Peroxide 175-192 latexin Homo sapiens 217-220 30442395-4 2018 Moreover, copper microelectrode doped with cobalt has demonstrated good reproducibility and long-run stability as well as sensitivity and selectivity towards determination of hydrogen peroxide (limit of detection-0.2 muM) and d-glucose (limit of detection-2.2 muM). Hydrogen Peroxide 175-192 latexin Homo sapiens 260-263 30140810-4 2018 Using dual-enzyme inorganic hybrid nanoflowers in the muPAD as nanobiocatalysts, which preserve the activity and enhance the stability of the enzymes, based on the H2O2-mediated catalytic oxidizing chromogenic reaction produced by glucose/uric acid, the developed multiplex paper-based nanobiocatalytic system is demonstrated to enable simultaneous and sensitive detection of glucose and uric acid with a detection limit of 60 and 25 muM, respectively. Hydrogen Peroxide 164-168 latexin Homo sapiens 434-437 29458613-5 2018 The sensor based on pompon-like Co9S8 displayed a wide linear response ranged from 1.50 muM to 8.51 mM, a favorable sensitivity of 20.80 muA mM-1 cm-2 and a detection limit of 0.45 muM (signal to noise ratio of 3) for hydrogen peroxide. Hydrogen Peroxide 218-235 latexin Homo sapiens 181-184 32254180-8 2018 The sensitivity of the sensor towards H2O2 was 0.557 muA mM-1, with a limit of detection (LOD) at 56.89 muM. Hydrogen Peroxide 38-42 latexin Homo sapiens 104-107 28527631-7 2018 A single treatment of cells with 100 muM hydrogen peroxide 24 h before analysis had no effect on wildtype cells, but normalized the otherwise increased respiration of knockout cells and significantly increased respiration in C684A cells. Hydrogen Peroxide 41-58 latexin Homo sapiens 37-40 29796900-4 2018 Electrochemical investigation demonstrates that the as-prepared modified microelectrode showed a quasi-reversible process toward the reduction of H2O2, which exhibited a linear range from 0.51 to 10.6 muM, with a limit of detection of 0.23 muM. Hydrogen Peroxide 146-150 latexin Homo sapiens 201-204 29796900-4 2018 Electrochemical investigation demonstrates that the as-prepared modified microelectrode showed a quasi-reversible process toward the reduction of H2O2, which exhibited a linear range from 0.51 to 10.6 muM, with a limit of detection of 0.23 muM. Hydrogen Peroxide 146-150 latexin Homo sapiens 240-243 29414085-4 2018 And the nanosheets exhibited excellent H2O2 detection property with a high sensitivity of about 320.3 uA mM-1 cm-2 and a low detection limit of 0.17 microM in a wide linear range of 5-6000 muM, and a fast response time (less than 2 s). Hydrogen Peroxide 39-43 latexin Homo sapiens 189-192 29567236-5 2018 The lowest H2O2 concentration could be measured by the as-prepared strip was 10 muM. Hydrogen Peroxide 11-15 latexin Homo sapiens 80-83 29397683-8 2018 The electrochemical response toward H2O2 exhibits a linear dependence on hydrogen peroxide concentration ranging between 10 muM and 700 muM. Hydrogen Peroxide 36-40 latexin Homo sapiens 124-127 29397683-8 2018 The electrochemical response toward H2O2 exhibits a linear dependence on hydrogen peroxide concentration ranging between 10 muM and 700 muM. Hydrogen Peroxide 36-40 latexin Homo sapiens 136-139 29397683-8 2018 The electrochemical response toward H2O2 exhibits a linear dependence on hydrogen peroxide concentration ranging between 10 muM and 700 muM. Hydrogen Peroxide 73-90 latexin Homo sapiens 124-127 29397683-8 2018 The electrochemical response toward H2O2 exhibits a linear dependence on hydrogen peroxide concentration ranging between 10 muM and 700 muM. Hydrogen Peroxide 73-90 latexin Homo sapiens 136-139 29035776-5 2018 Screening results indicated that compounds 4, 5, 12, 13 showed moderate neuroprotective effects on H2O2-induced cellular damage in human neuroblastoma SH-SY5Y cells (10 muM). Hydrogen Peroxide 99-103 latexin Homo sapiens 169-172 29594683-4 2018 The color change can be observed visually if the concentration of H2O2 is 2 muM or higher. Hydrogen Peroxide 66-70 latexin Homo sapiens 76-79 29411011-12 2018 CsA (10 muM) significantly inhibited the H2O2-induced expression of NFATc3 in normal and glaucoma LC cells. Hydrogen Peroxide 41-45 latexin Homo sapiens 8-11 30023768-7 2018 The linear range toward H2O2 sensing is from 0.3 to 2338 muM, and the limit of detection (LOD) is 0.1 muM. Hydrogen Peroxide 24-28 latexin Homo sapiens 57-60 30023768-7 2018 The linear range toward H2O2 sensing is from 0.3 to 2338 muM, and the limit of detection (LOD) is 0.1 muM. Hydrogen Peroxide 24-28 latexin Homo sapiens 102-105 28211035-5 2017 Our results showed that low H2O2 concentrations (20 muM) can promote FLS growth and that Res significantly inhibited FLS activity. Hydrogen Peroxide 28-32 latexin Homo sapiens 52-55 29207575-3 2017 By further evaluating their cytoprotective activity against H2O2 induced injury in EA.hy926 cells, 14 target bromophenols showed moderate-to-potent activity with EC50 values in the range of 0.9-6.3 muM, which were stronger than that of quercetin (EC50: 18.0 muM), a positive reference compound. Hydrogen Peroxide 60-64 latexin Homo sapiens 198-201 29207575-3 2017 By further evaluating their cytoprotective activity against H2O2 induced injury in EA.hy926 cells, 14 target bromophenols showed moderate-to-potent activity with EC50 values in the range of 0.9-6.3 muM, which were stronger than that of quercetin (EC50: 18.0 muM), a positive reference compound. Hydrogen Peroxide 60-64 latexin Homo sapiens 258-261 28882760-5 2017 Using an oxygen sensor, the oxygen concentration was found to increase with a rate up to 0.4muM/min, which was dependent upon the concentrations of hydrogen peroxide and the Mn-protein. Hydrogen Peroxide 148-165 latexin Homo sapiens 92-95 28689095-6 2017 Results showed a strong efficacy of the tested compounds, even at the lower doses, in counteracting the induced oxidative stress (50 muM of H2O2) and in preventing ROS formation. Hydrogen Peroxide 140-144 latexin Homo sapiens 133-136 28474898-5 2017 The amino-functionalized AIS QDs show high sensitivity and specificity for H2O2 and glucose with detection limits of 0.42 and 0.90 muM, respectively. Hydrogen Peroxide 75-79 latexin Homo sapiens 131-134 28773209-9 2017 The measured catalysis currents increase linearly with the H2O2 concentration in a wide range of 25-350 muM with a correlation coefficient 0.99. Hydrogen Peroxide 59-63 latexin Homo sapiens 104-107 28773209-12 2017 On the other hand, the magnetoelastic measurements show a small linear mass increase versus the H2O2 concentration with a slope of 152 ng/muM, which is probably due to H2O2 adsorption in ZnO during the electrochemical reaction. Hydrogen Peroxide 96-100 latexin Homo sapiens 138-141 28773209-12 2017 On the other hand, the magnetoelastic measurements show a small linear mass increase versus the H2O2 concentration with a slope of 152 ng/muM, which is probably due to H2O2 adsorption in ZnO during the electrochemical reaction. Hydrogen Peroxide 168-172 latexin Homo sapiens 138-141 29088826-5 2017 Our experiments demonstrated that, first, exposure to 100muM hydrogen peroxide decreased cell viability, DNA synthesis, mitochondrial respiration and antioxidant function, and increased apoptosis. Hydrogen Peroxide 61-78 latexin Homo sapiens 57-60 28639653-4 2017 Under optimal conditions, it showed a speed of 420 mum s-1 in 2% H2O2 and even 51 mum s-1 in 0.25% H2O2. Hydrogen Peroxide 65-69 latexin Homo sapiens 51-54 28639653-4 2017 Under optimal conditions, it showed a speed of 420 mum s-1 in 2% H2O2 and even 51 mum s-1 in 0.25% H2O2. Hydrogen Peroxide 99-103 latexin Homo sapiens 51-54 28639653-4 2017 Under optimal conditions, it showed a speed of 420 mum s-1 in 2% H2O2 and even 51 mum s-1 in 0.25% H2O2. Hydrogen Peroxide 99-103 latexin Homo sapiens 82-85 28474898-6 2017 A linear correlation was established between PL intensity and concentration of H2O2 in the ranges of 0.5-10 muM and 10-300 muM, while the linear ranges were 1-10 muM and 10-1000 muM for detection of glucose. Hydrogen Peroxide 79-83 latexin Homo sapiens 108-111 28474898-6 2017 A linear correlation was established between PL intensity and concentration of H2O2 in the ranges of 0.5-10 muM and 10-300 muM, while the linear ranges were 1-10 muM and 10-1000 muM for detection of glucose. Hydrogen Peroxide 79-83 latexin Homo sapiens 123-126 28474898-6 2017 A linear correlation was established between PL intensity and concentration of H2O2 in the ranges of 0.5-10 muM and 10-300 muM, while the linear ranges were 1-10 muM and 10-1000 muM for detection of glucose. Hydrogen Peroxide 79-83 latexin Homo sapiens 123-126 28474898-6 2017 A linear correlation was established between PL intensity and concentration of H2O2 in the ranges of 0.5-10 muM and 10-300 muM, while the linear ranges were 1-10 muM and 10-1000 muM for detection of glucose. Hydrogen Peroxide 79-83 latexin Homo sapiens 123-126 28160681-2 2017 The results show that the soluble iron in the investigated water samples was sufficiently effective for reaction with H2O2 in the simulated rainwater-affected stagnant water to produce OH (Fenton reaction), which inactivated coliform bacteria even at a H2O2 dose as low as 5 muM within just 1 min of contact time. Hydrogen Peroxide 118-122 latexin Homo sapiens 275-278 28160681-5 2017 In the presence of H2O2 at a dose of 20 muM, Fenton-driven chemical oxidation appeared to outplay the impediment of biodegradation caused by inhibited microbial activities in terms of removing total polycyclic aromatic hydrocarbons from the water column. Hydrogen Peroxide 19-23 latexin Homo sapiens 40-43 28503967-4 2017 Interestingly, pre-treatment of SH-SY5Y cells with 100 muM TD prevented cell death and suppressed intracellular ROS generation evoked by the addition of hydrogen peroxide (H2O2). Hydrogen Peroxide 153-170 latexin Homo sapiens 55-58 28503967-4 2017 Interestingly, pre-treatment of SH-SY5Y cells with 100 muM TD prevented cell death and suppressed intracellular ROS generation evoked by the addition of hydrogen peroxide (H2O2). Hydrogen Peroxide 172-176 latexin Homo sapiens 55-58 28248102-4 2017 Compounds 1-3, 6-8, 12, and 13 displayed significant effects against hydrogen peroxide-induced neurotoxicity in SH-SY5Y cells at 10 muM. Hydrogen Peroxide 69-86 latexin Homo sapiens 132-135 28490955-2 2017 MTT assay showed that hydrogen peroxide treatment at a concentration of 100 muM caused a significant (p < 0.005) reduction in the viability of MG63 cells. Hydrogen Peroxide 22-39 latexin Homo sapiens 76-79 28490955-3 2017 However, reduction in cell viability caused by 100 muM concentration of hydrogen peroxide was completely prevented on incubation with 30 muM dose of dihydromyricetin. Hydrogen Peroxide 72-89 latexin Homo sapiens 51-54 28490955-3 2017 However, reduction in cell viability caused by 100 muM concentration of hydrogen peroxide was completely prevented on incubation with 30 muM dose of dihydromyricetin. Hydrogen Peroxide 72-89 latexin Homo sapiens 137-140 28490955-4 2017 Treatment with 100 muM concentration of hydrogen peroxide for 24 h led to condensation of chromatin material, rounding of cell shape and detachment of cells. Hydrogen Peroxide 40-57 latexin Homo sapiens 19-22 28490955-5 2017 The results from flow cytometry using annexin V-FITC and PI double staining showed apoptosis induction in 47.84 +- 5.21% cells on treatment with 100 muM concentration of hydrogen peroxide compared to 2.32 +- 0.54% in controlcells. Hydrogen Peroxide 170-187 latexin Homo sapiens 149-152 28490955-6 2017 The apoptotic alterations in MG63 cell morphology were prevented significantly on pre-treatment with 30 muM doses of dihydromyricetin for 48 h. Annexin V-FITC and PI staining showed reduction of hydrogen peroxide induced apoptotic cell percentage to 3.07 +- 0.86% on pre-treatment of MG63 cells with 30 muM dose of dihydromyricetin. Hydrogen Peroxide 195-212 latexin Homo sapiens 104-107 28490955-6 2017 The apoptotic alterations in MG63 cell morphology were prevented significantly on pre-treatment with 30 muM doses of dihydromyricetin for 48 h. Annexin V-FITC and PI staining showed reduction of hydrogen peroxide induced apoptotic cell percentage to 3.07 +- 0.86% on pre-treatment of MG63 cells with 30 muM dose of dihydromyricetin. Hydrogen Peroxide 195-212 latexin Homo sapiens 303-306 28490955-7 2017 Western blot analysis showed a significant increase in the activation of caspase-3 and -9 on treatment of MG63 cells for 24 h with 100 muM concentration of hydrogen peroxide. Hydrogen Peroxide 156-173 latexin Homo sapiens 135-138 28490955-8 2017 The expression level of Bcl-2 was decreased significantly by 100 muM concentration of hydrogen peroxide in MG63 cells. Hydrogen Peroxide 86-103 latexin Homo sapiens 65-68 28490955-9 2017 However, pre-treatment of MG63 cells with 30 muM dose of dihydromyricetin for 48 h significantly prevented hydrogen peroxide induced increase in caspase-3 and -9 levels and reduction in Bcl-2 level. Hydrogen Peroxide 107-124 latexin Homo sapiens 45-48 27975200-3 2017 The results indicated that 265 nm UV/H2O2 treatment had a high removal efficiency of MC-LR ([MC-LR] = 0.1 muM, apparent rate constants reached 0.2077 min-1, half-time at 3.3 min). Hydrogen Peroxide 37-41 latexin Homo sapiens 106-109 27254786-3 2016 The AuPd@GR nanohybrids exhibited excellent catalytic activity towards H2O2 detection with a wide detection range (5muM-11.5mM), high sensitivity (186.86muAmM(-1)cm(-2)), low limit of detection (1muM), fast response (3s), and long-term working stability (2500s). Hydrogen Peroxide 71-75 latexin Homo sapiens 116-119 28452733-5 2017 The viability of Jurkat cells incubated for 24 hours under acquit oxidative stress conditions dose-depenently, monotonically decreased (irreversibly at 100 muM of H2O2 and reaches the 30% of intact Jurkat cells viability level at 50 muM of H2O2). Hydrogen Peroxide 163-167 latexin Homo sapiens 156-159 28452733-5 2017 The viability of Jurkat cells incubated for 24 hours under acquit oxidative stress conditions dose-depenently, monotonically decreased (irreversibly at 100 muM of H2O2 and reaches the 30% of intact Jurkat cells viability level at 50 muM of H2O2). Hydrogen Peroxide 163-167 latexin Homo sapiens 233-236 27866421-9 2017 DPBF responds to hydrogen peroxide in a very specific way with the limits of detection and quantitation of 88 and 122.8 muM, respectively. Hydrogen Peroxide 17-34 latexin Homo sapiens 120-123 28118826-6 2017 Concentrations of NAC >=1 muM reduced the pro-oxidant response (peroxidase activity, hydrogen peroxide, malondialdehyde, nitric oxide), and improved the anti-oxidant response (total anti-oxidant capacity, glutathione, superoxide dismutase) induced by LPS. Hydrogen Peroxide 88-105 latexin Homo sapiens 29-32 27308956-4 2017 A preliminary bioassay revealed that compounds 3 and 7 exhibited significant protective effects against hydrogen peroxide-induced damage in human retinal endothelial cells (HRECs) with the concentration of 10 muM, respectively. Hydrogen Peroxide 104-121 latexin Homo sapiens 209-212 27612728-4 2016 Amperometric study using ERGO/GCE showed high sensitivity (0.3muA/muM) and faster response upon the addition of H2O2 at an applied potential of -0.25V vs. Ag/AgCl. Hydrogen Peroxide 112-116 latexin Homo sapiens 66-69 32263534-5 2016 Under optimum conditions, the HN-RGO/AuNP-modified electrode shows a wide linear response ranges from 0.05 muM to 518.15 muM towards H2O2 with a fast response time (3 s). Hydrogen Peroxide 133-137 latexin Homo sapiens 107-110 32263534-5 2016 Under optimum conditions, the HN-RGO/AuNP-modified electrode shows a wide linear response ranges from 0.05 muM to 518.15 muM towards H2O2 with a fast response time (3 s). Hydrogen Peroxide 133-137 latexin Homo sapiens 121-124 27556215-6 2016 Curcumin treatment at concentrations between 1 and 20 muM reduced the production of iROS in H2O2-exposed TM cells in a dose-dependent manner. Hydrogen Peroxide 92-96 latexin Homo sapiens 54-57 27351826-5 2016 In this work we report that H2O2 at low doses (1 pM-1muM) exerts an inhibitory effect on TO901317-induced mRNA expression of LXRalpha and of its target genes encoding the ATP-binding cassette (ABC) transporters ABCA1 and ABCG1, and the sterol regulatory element-binding protein 1c (SREBP1c). Hydrogen Peroxide 28-32 latexin Homo sapiens 53-56 26952442-5 2016 The sensitivity and detection limit for H2O2 at the operating potential of +0.35 V were 167 nA muM(-1)cm(-2) and 1.2 muM, respectively and better than those obtained at the operating potential of -0.25 V (68 nA muM(-1)cm(-2) and 14 muM). Hydrogen Peroxide 40-44 latexin Homo sapiens 95-98 26916736-8 2016 The high performance was indicated by some of the key parameters, for example the linear H2O2 concentration response range (1-30 muM), the detection limit (100 nM), and the high amperometric sensitivity (5 A cm(-2) M(-1)). Hydrogen Peroxide 89-93 latexin Homo sapiens 129-132 26952442-5 2016 The sensitivity and detection limit for H2O2 at the operating potential of +0.35 V were 167 nA muM(-1)cm(-2) and 1.2 muM, respectively and better than those obtained at the operating potential of -0.25 V (68 nA muM(-1)cm(-2) and 14 muM). Hydrogen Peroxide 40-44 latexin Homo sapiens 117-120 27110794-5 2016 Under the optimal reaction conditions, the resulting sensor displayed a good response to H2O2 with a linear range of 1 to 500 muM, and a detection limit of 1 muM at a signal-to-noise ratio of 3. Hydrogen Peroxide 89-93 latexin Homo sapiens 126-129 26804444-3 2016 Exposure of cells to glutamate (60-80 mM) or H2O2 (200-300 muM) for 24 h decreased cellular viability and increased dichlorofluorescein (DCF) fluorescence (indicative of increased reactive oxygen species, ROS) and nitric oxide (NO) production (assessed by mono-nitrogen oxides, NOx, levels). Hydrogen Peroxide 45-49 latexin Homo sapiens 59-62 26804444-4 2016 Creatine (1-10 mM) or MK-801 (0.1-10 muM) reduced glutamate- and H2O2-induced toxicity. Hydrogen Peroxide 65-69 latexin Homo sapiens 37-40 27110794-5 2016 Under the optimal reaction conditions, the resulting sensor displayed a good response to H2O2 with a linear range of 1 to 500 muM, and a detection limit of 1 muM at a signal-to-noise ratio of 3. Hydrogen Peroxide 89-93 latexin Homo sapiens 158-161 26830534-4 2016 The mechanism likely involves inhibition of catalase activity by nitrite (IC50, 9 muM), which allows H2O2 to accumulate and oxidize Cys moieties of oxyhemoglobin and erythrocytic GSH to form HbSSG in addition to GSSG. Hydrogen Peroxide 101-105 latexin Homo sapiens 82-85 27019266-6 2016 The retinoic acid differentiated SH-S cell line (10 muM) shows a clear apoptosis when treated with H2O2 150 muM, with a Bax/Bcl-2 ratio of 3.75 (SD 0.80) in contrast to the differentiated control cells subjected to H2O2 and with extract, which have the same ratio of 1.02 (SD 0.01-0.03). Hydrogen Peroxide 99-103 latexin Homo sapiens 52-55 26593482-1 2016 Three nationally prominent commercial powdered infant formulas generated hydrogen peroxide, ranging from 10.46 to 11.62 muM, when prepared according to the manufacturer"s instructions. Hydrogen Peroxide 73-90 latexin Homo sapiens 120-123 27019266-6 2016 The retinoic acid differentiated SH-S cell line (10 muM) shows a clear apoptosis when treated with H2O2 150 muM, with a Bax/Bcl-2 ratio of 3.75 (SD 0.80) in contrast to the differentiated control cells subjected to H2O2 and with extract, which have the same ratio of 1.02 (SD 0.01-0.03). Hydrogen Peroxide 99-103 latexin Homo sapiens 108-111 26511954-7 2016 The absorption of PDA-PBA at 650 nm is linearly related to the concentration of H2O2 and a detection limit of ~5 muM could be achieved. Hydrogen Peroxide 80-84 latexin Homo sapiens 113-116 26745155-5 2016 H2O2 induced a significant decrease in rate constant for SO4= uptake at both 100 and 300 muM H2O2. Hydrogen Peroxide 0-4 latexin Homo sapiens 89-92 26745155-5 2016 H2O2 induced a significant decrease in rate constant for SO4= uptake at both 100 and 300 muM H2O2. Hydrogen Peroxide 93-97 latexin Homo sapiens 89-92 26362642-2 2016 In this study, a simulated experiment was conducted to examine the effects of hydrogen peroxide (at a concentration range of 5-50 muM) on the abiotic oxidation of arsenopyrite cubes. Hydrogen Peroxide 78-95 latexin Homo sapiens 130-133 26770658-4 2016 Experiment 2 was designed to study a high (50 muM) and low dose (12.5 muM) of H2O2 compared to a control (0 muM). Hydrogen Peroxide 78-82 latexin Homo sapiens 70-73 26770658-4 2016 Experiment 2 was designed to study a high (50 muM) and low dose (12.5 muM) of H2O2 compared to a control (0 muM). Hydrogen Peroxide 78-82 latexin Homo sapiens 70-73 26605980-8 2015 Multiple experimental approaches showed that exposure to 1,2-NQ at concentrations as low as 3 muM induces H2O2-dependent protein sulfenylation in BEAS-2B cells. Hydrogen Peroxide 106-110 latexin Homo sapiens 94-97 26581173-10 2015 H2O2 was higher in patients with ARDS, compared to controls (0.09 (0.06-0.12) muM versus 0.03 (0.01-0.09) muM, p = 0.043), while no difference was found in proteins content, 8-isoprostane, 4-hydroxy-2-nonhenal. Hydrogen Peroxide 0-4 latexin Homo sapiens 78-81 26514845-4 2015 Using CuNCs as probes, H2O2 was determined in the range from 1 muM to 50 muM based on a linear decrease of fluorescence intensity as well as a detection limit of 0.2 muM with a signal-to-noise ratio of 3. Hydrogen Peroxide 23-27 latexin Homo sapiens 63-66 26514845-4 2015 Using CuNCs as probes, H2O2 was determined in the range from 1 muM to 50 muM based on a linear decrease of fluorescence intensity as well as a detection limit of 0.2 muM with a signal-to-noise ratio of 3. Hydrogen Peroxide 23-27 latexin Homo sapiens 73-76 26514845-4 2015 Using CuNCs as probes, H2O2 was determined in the range from 1 muM to 50 muM based on a linear decrease of fluorescence intensity as well as a detection limit of 0.2 muM with a signal-to-noise ratio of 3. Hydrogen Peroxide 23-27 latexin Homo sapiens 73-76 26581173-10 2015 H2O2 was higher in patients with ARDS, compared to controls (0.09 (0.06-0.12) muM versus 0.03 (0.01-0.09) muM, p = 0.043), while no difference was found in proteins content, 8-isoprostane, 4-hydroxy-2-nonhenal. Hydrogen Peroxide 0-4 latexin Homo sapiens 106-109 26249610-3 2015 The resulting sensor exhibited a good response to hydrogen peroxide over linear range from 0.2 to 60.0muM with a limit of detection of 0.08muM, good reproducibility, long-term stability and negligible interference from ascorbic acid, uric acid and dopamine. Hydrogen Peroxide 50-67 latexin Homo sapiens 102-105 26535076-4 2015 Although H2O2 (200 muM) increased intracellular ROS levels in human MSCs, lycopene (10 muM) pretreatment suppressed H2O2-induced ROS generation and increased survival. Hydrogen Peroxide 116-120 latexin Homo sapiens 87-90 26469539-4 2015 The resulting biosensor showed good electrochemical activity toward the reduction of H2O2 with low detection limit down to 1 muM (S/N = 3) and wide linear detection ranging from 0.01 mM to 3.5 mM (R(2) = 0.990). Hydrogen Peroxide 85-89 latexin Homo sapiens 125-128 26003691-3 2015 The CQDs have an average size of 3.6 nm in diameter with narrow size distribution, and can be used as highly selective and sensitive fluorescence probes for hydrogen peroxide and glucose, with limits of detection of 3.8 muM and 3.5 muM, respectively. Hydrogen Peroxide 157-174 latexin Homo sapiens 232-235 26399738-10 2015 The detecting limit for H2O2 was estimated at 2.9 and 5.0 muM in vitro and in cultured cells, respectively. Hydrogen Peroxide 24-28 latexin Homo sapiens 58-61 32262645-7 2015 The fluorescence quenching of MCPs@GNR can be achieved by addition of H2O2 which shows linearity over a range of increasing concentration of 10 muM to 150 muM. Hydrogen Peroxide 70-74 latexin Homo sapiens 144-147 32262645-7 2015 The fluorescence quenching of MCPs@GNR can be achieved by addition of H2O2 which shows linearity over a range of increasing concentration of 10 muM to 150 muM. Hydrogen Peroxide 70-74 latexin Homo sapiens 155-158 25818356-4 2015 The proposed PdCo/CNF-based biosensor showed excellent analytical performances toward hydrogen peroxide (detection limit: 0.1 muM; linear range: 0.2 muM-23.5 mM) and nitrite (detection limit: 0.2 muM; linear range: 0.4-30 muM and 30-400 muM). Hydrogen Peroxide 86-103 latexin Homo sapiens 126-129 26213787-4 2015 The optimized ECL imaging system showed that hydrogen peroxide as low as 10 muM was visible and the efflux of hydrogen peroxide from cells could be determined. Hydrogen Peroxide 45-62 latexin Homo sapiens 76-79 26225726-4 2015 Under optimal conditions, the resulting biosensor displayed a good response for H2O2 with a linear range of 0.2 to 12.8 mM, and a detection limit of 7.8 muM at a signal-to-noise ratio of 3. Hydrogen Peroxide 80-84 latexin Homo sapiens 153-156 25818356-4 2015 The proposed PdCo/CNF-based biosensor showed excellent analytical performances toward hydrogen peroxide (detection limit: 0.1 muM; linear range: 0.2 muM-23.5 mM) and nitrite (detection limit: 0.2 muM; linear range: 0.4-30 muM and 30-400 muM). Hydrogen Peroxide 86-103 latexin Homo sapiens 149-152 25818356-4 2015 The proposed PdCo/CNF-based biosensor showed excellent analytical performances toward hydrogen peroxide (detection limit: 0.1 muM; linear range: 0.2 muM-23.5 mM) and nitrite (detection limit: 0.2 muM; linear range: 0.4-30 muM and 30-400 muM). Hydrogen Peroxide 86-103 latexin Homo sapiens 149-152 25818356-4 2015 The proposed PdCo/CNF-based biosensor showed excellent analytical performances toward hydrogen peroxide (detection limit: 0.1 muM; linear range: 0.2 muM-23.5 mM) and nitrite (detection limit: 0.2 muM; linear range: 0.4-30 muM and 30-400 muM). Hydrogen Peroxide 86-103 latexin Homo sapiens 149-152 25818356-4 2015 The proposed PdCo/CNF-based biosensor showed excellent analytical performances toward hydrogen peroxide (detection limit: 0.1 muM; linear range: 0.2 muM-23.5 mM) and nitrite (detection limit: 0.2 muM; linear range: 0.4-30 muM and 30-400 muM). Hydrogen Peroxide 86-103 latexin Homo sapiens 149-152 25774435-8 2015 On the basis of the high activity of CeO2/nanotube-TiO2, the reaction provides a simple method for colorimetric detection of H2O2 and glucose with the detection limits of 3.2 and 6.1 muM, respectively. Hydrogen Peroxide 125-129 latexin Homo sapiens 183-186 32262292-4 2015 With such a process, as low as 68 nM H2O2 could be detected with a linear range from 0.1 to 100 muM. Hydrogen Peroxide 37-41 latexin Homo sapiens 96-99 25868604-6 2015 The approach achieves a low detection limit of 0.1 muM for H2O2. Hydrogen Peroxide 59-63 latexin Homo sapiens 51-54 25660330-13 2015 Treatment with 20 muM also elevated GR activity after in vitro incubation at 37 C. Electrophoretic profiles revealed that incubation with ibogaine mitigates H2O2 mediated suppression of SOD1 activity. Hydrogen Peroxide 157-161 latexin Homo sapiens 18-21 32262778-4 2015 The bi-directional sensor showed a linear range from 0.05 muM to 17.5 mM with a detection limit of 0.02 muM (S/N = 3) at an applied potential of +0.5 V and a linear range from 0.5 muM to 110 mM with a detection limit of 0.25 muM (S/N = 3) at an applied potential of -0.3 V. The proposed sensor was tested to determine H2O2 released from living cells and shows good application potential in biological electrochemistry. Hydrogen Peroxide 318-322 latexin Homo sapiens 58-61 32262778-4 2015 The bi-directional sensor showed a linear range from 0.05 muM to 17.5 mM with a detection limit of 0.02 muM (S/N = 3) at an applied potential of +0.5 V and a linear range from 0.5 muM to 110 mM with a detection limit of 0.25 muM (S/N = 3) at an applied potential of -0.3 V. The proposed sensor was tested to determine H2O2 released from living cells and shows good application potential in biological electrochemistry. Hydrogen Peroxide 318-322 latexin Homo sapiens 104-107 32262778-4 2015 The bi-directional sensor showed a linear range from 0.05 muM to 17.5 mM with a detection limit of 0.02 muM (S/N = 3) at an applied potential of +0.5 V and a linear range from 0.5 muM to 110 mM with a detection limit of 0.25 muM (S/N = 3) at an applied potential of -0.3 V. The proposed sensor was tested to determine H2O2 released from living cells and shows good application potential in biological electrochemistry. Hydrogen Peroxide 318-322 latexin Homo sapiens 104-107 32262778-4 2015 The bi-directional sensor showed a linear range from 0.05 muM to 17.5 mM with a detection limit of 0.02 muM (S/N = 3) at an applied potential of +0.5 V and a linear range from 0.5 muM to 110 mM with a detection limit of 0.25 muM (S/N = 3) at an applied potential of -0.3 V. The proposed sensor was tested to determine H2O2 released from living cells and shows good application potential in biological electrochemistry. Hydrogen Peroxide 318-322 latexin Homo sapiens 104-107 25818144-4 2015 The linearity between the analyte concentration and absorption ranged from 20 to 1170 muM for H2O2 and 25 to 375 muM for glucose with a detection limit of 5.3 muM for H2O2 and 16 muM for glucose. Hydrogen Peroxide 94-98 latexin Homo sapiens 86-89 25818144-4 2015 The linearity between the analyte concentration and absorption ranged from 20 to 1170 muM for H2O2 and 25 to 375 muM for glucose with a detection limit of 5.3 muM for H2O2 and 16 muM for glucose. Hydrogen Peroxide 167-171 latexin Homo sapiens 113-116 25818144-4 2015 The linearity between the analyte concentration and absorption ranged from 20 to 1170 muM for H2O2 and 25 to 375 muM for glucose with a detection limit of 5.3 muM for H2O2 and 16 muM for glucose. Hydrogen Peroxide 167-171 latexin Homo sapiens 113-116 25818144-4 2015 The linearity between the analyte concentration and absorption ranged from 20 to 1170 muM for H2O2 and 25 to 375 muM for glucose with a detection limit of 5.3 muM for H2O2 and 16 muM for glucose. Hydrogen Peroxide 167-171 latexin Homo sapiens 113-116 25688934-5 2015 Cytochrome C-functionalized electrodes prepared using the induced dual nanoelectrospray process showed bioactivity toward aqueous solutions of hydrogen peroxide below 50 muM. Hydrogen Peroxide 143-160 latexin Homo sapiens 170-173 25262340-4 2015 It was determined at the characterization studies on the biosensor that linear results are obtained between the ranges of 0.1muM to 70.0muM for H2O2 concentration and 1-250muM for NO2(-). Hydrogen Peroxide 144-148 latexin Homo sapiens 125-128 25588103-4 2015 After pretreatment at the concentrations of 5 and 10 muM, oxyresveratrol increased cell viability, exhibited significant suppressions on UVA- or H2O2-induced cellular ROS. Hydrogen Peroxide 145-149 latexin Homo sapiens 53-56 25686273-8 2015 The result indicated that 23 and 24 significantly inhibited H2O2-induced decrease of the cell mitochondrial membrane potential (DeltaPsim) at 25 muM. Hydrogen Peroxide 60-64 latexin Homo sapiens 145-148 25611970-7 2015 H2O2 is thus consumed in a catalytic cycle and leads to less efficient HOBr scavenging at even low iodide concentrations (<1 muM). Hydrogen Peroxide 0-4 latexin Homo sapiens 128-131 32264480-8 2015 The lowest detection limits for H2O2 and glucose were 0.6 nM and 0.6 muM, respectively. Hydrogen Peroxide 32-36 latexin Homo sapiens 69-72 25447319-1 2015 A new nano contrast agent has been prepared incorporating a molecular magnet in oxidation-responsive nanoparticles; this system has shown a remarkable sensitivity to hydrogen peroxide (detection down to at least 40 muM), which was used as a model reactive oxygen species. Hydrogen Peroxide 166-183 latexin Homo sapiens 215-218 25527723-7 2015 We showed that the linear detection range for H2O2-induced DNA damage in human lymphoblastoid cells is between 30 and 100 muM, and that within this range, inter-sample coefficient of variance was between 5 and 10%. Hydrogen Peroxide 46-50 latexin Homo sapiens 122-125 25269106-5 2014 The rate of superoxide anion radical (O2(-)) production under Fe(III)-oxalate/H2O2/UV (350 nm) was 0.19 +- 0.02 muM/min with a steady-state concentration of 5.43 +- 0.473 x 10(-10) M. Detailed product studies using liquid chromatography coupled to Q-TOF/MS demonstrate both reduction (multiple dehalogenations) and oxidation (aromatic ring and side chains) contribute to the degradation pathways. Hydrogen Peroxide 78-82 latexin Homo sapiens 112-115 25390796-8 2014 With optimal conditions, the approach achieves a low detection limit of 0.10 muM for H2O2. Hydrogen Peroxide 85-89 latexin Homo sapiens 77-80 25326781-3 2014 Zinc carnosine at the concentration 16 muM was optimal in protecting cells from hydrogen peroxide-induced cytotoxicity and gave the lowest percentage of apoptotic and necrotic cells. Hydrogen Peroxide 80-97 latexin Homo sapiens 39-42 25326781-4 2014 Results showed that zinc carnosine was able to induce glutathione production and protect cells from hydrogen peroxide-induced oxidative stress at all concentration and the highest protection was observed at 32-muM zinc carnosine culture. Hydrogen Peroxide 100-117 latexin Homo sapiens 210-213 25326781-5 2014 Cytokinesis-block micronucleus cytome assay showed that cells cultured with 4-32 muM of zinc carnosine showed significant reduction in micronuclei formation, nucleoplasmic bridges and nuclear bud frequencies (p < 0.05), suggesting that these concentrations maybe optimal in protecting cells from hydrogen peroxide-induced DNA damage. Hydrogen Peroxide 299-316 latexin Homo sapiens 81-84 25196578-5 2014 The detecting limit of NP1 toward H2O2 is estimated as 0.17 muM. Hydrogen Peroxide 34-38 latexin Homo sapiens 60-63 25123289-8 2014 In cultured human umbilical vein endothelial cells (HUVECs), 1 muM metformin reversed AGE-induced increase of ROS and attenuated AGE- and H2O2- induced downregulation of IKCa and SKCa after long-term incubation (>24 hours). Hydrogen Peroxide 138-142 latexin Homo sapiens 63-66 24887508-5 2014 The developed sensor gave a linear response over a wide concentration range of H2O2 (0.68-78.6 muM). Hydrogen Peroxide 79-83 latexin Homo sapiens 95-98 24857484-6 2014 The detection limit (S/N=3) for H2O2 was about 1 muM. Hydrogen Peroxide 32-36 latexin Homo sapiens 49-52 32261860-7 2014 A linear relationship between the anodic current and [H2O2] allows quantitative determination of the latter with a detection limit and sensitivity of 5 muM and 0.7 muA muM-1, respectively. Hydrogen Peroxide 54-58 latexin Homo sapiens 152-155 32261661-3 2014 The as-made NP-PdCr alloy exhibits high sensing performance toward H2O2, such as a wide linear range from 0.1 to 1.9 mM, fast amperometric response, and a low detection limit of 3.1 muM. Hydrogen Peroxide 67-71 latexin Homo sapiens 182-185 24995368-2 2014 It was corroborated that changes in the concentration of hydrogen peroxide as small as 0.05 muM could lead to nanoparticle solutions of completely different tonality. Hydrogen Peroxide 57-74 latexin Homo sapiens 92-95 25033439-5 2014 In Cu(I)-H2O2 system (Fenton reaction conditions) BTPA compounds 6, 8, and 10 (NCH2Ph) were identified as most potent antioxidants (IC50 32, 56, and 29 muM, respectively), whereas BOPA analogues 7, 9 (NEt), and 11 (NCH2Ph) were found to be poor antioxidants. Hydrogen Peroxide 9-13 latexin Homo sapiens 152-155 25033439-6 2014 In Fe(II)-H2O2 system, IC50 values for both BTPA and BOPA compounds exceeded 500 muM indicating high selectivity to Cu(I) versus the borderline Fe(II)-ion. Hydrogen Peroxide 10-14 latexin Homo sapiens 81-84 24388509-8 2014 Impact of exogenous nitric oxide donor (sodium nitroprusside/SNP) was therefore tested and results showed amelioration of 1000 muM Mn-induced oxidative stress in seedlings (decrease in H2O2 and increase in NO content while antioxidative enzyme activities were variably affected) concomitantly with depleted Mn accumulation. Hydrogen Peroxide 185-189 latexin Homo sapiens 127-130 24890692-4 2014 In addition, NP-PdFe performs high sensing performance towards H2O2 in a wide linear range from 0.5 to 6 mM with a low detection limit of 2.1 muM. Hydrogen Peroxide 63-67 latexin Homo sapiens 142-145 24315179-1 2014 A microcosm experiment was conducted to examine the effects of hydrogen peroxide (at a concentration range of 5-50 muM) on the release of arsenic from the dissolution of arsenopyrite, a dominant arsenic-bearing mineral occurring in natural environments. Hydrogen Peroxide 63-80 latexin Homo sapiens 115-118 24410662-2 2014 We found that electron paramagnetic resonance (EPR)-monitored inhibition of OH radicals production from H2O2, in an Fe(2+)-H2O2 system, by bisphosphate derivatives 1, 3, and 5 (IC50 = 36, 24, and 40 muM, respectively), was more effective than it was by ethylenediaminetetraacetic acid (EDTA), by a factor of 1.5, 2, and 1.4, respectively. Hydrogen Peroxide 104-108 latexin Homo sapiens 199-202 24615460-7 2014 The spiky Pt nanosphere decorated G/S film was directly used as a H2O2 electrode with a sensitivity of 0.56 mA mM(-1) cm(-2), a linear range of 0-2.5 mM and an ultralow detection limit of 0.2 muM (S/N = 3). Hydrogen Peroxide 66-70 latexin Homo sapiens 192-195 24512566-4 2014 The prepared PtCu NC electrode exhibited excellent electrocatalytic activity towards H2O2, with a wide liner range from 5 muM to 22.25 mM, a relatively high sensitivity of 295.3 muA mM-1 cm-2, and a low detection limit of 5 muM (S/N = 3). Hydrogen Peroxide 85-89 latexin Homo sapiens 122-125 24512566-4 2014 The prepared PtCu NC electrode exhibited excellent electrocatalytic activity towards H2O2, with a wide liner range from 5 muM to 22.25 mM, a relatively high sensitivity of 295.3 muA mM-1 cm-2, and a low detection limit of 5 muM (S/N = 3). Hydrogen Peroxide 85-89 latexin Homo sapiens 224-227 32261329-5 2013 The fabricated H2O2 biosensor reveals a wide linear range from 0.25 to 22.5 mM, low detection limit of 6.2 muM (S/N = 3), high selectivity, and long-term stability. Hydrogen Peroxide 15-19 latexin Homo sapiens 107-110 24055680-6 2014 Under the optimized experimental conditions, the linear ranges for H2O2 and glucose are 0.5-10 muM and 10-100 muM, respectively. Hydrogen Peroxide 67-71 latexin Homo sapiens 95-98 24055680-6 2014 Under the optimized experimental conditions, the linear ranges for H2O2 and glucose are 0.5-10 muM and 10-100 muM, respectively. Hydrogen Peroxide 67-71 latexin Homo sapiens 110-113 24055680-7 2014 And the detection limits for H2O2 and glucose are 0.4 and 8 muM, respectively. Hydrogen Peroxide 29-33 latexin Homo sapiens 60-63 24602819-5 2014 In cultured fibroblasts taken from human skin, hydrogen peroxide (100-1000 muM) damaged 62-92% of the cells compared to only 35-47% when the cells were preincubated in extract (200 mug/ml) for 24 h. UVA (40 J/cm2) irradiation of human fibroblasts damaged 25% of the cells but the death rate was reduced to 10% with extract. Hydrogen Peroxide 47-64 latexin Homo sapiens 75-78 23787095-7 2013 Moreover, the resulting electrode exhibited excellent electrocatalytic ability towards the reduction of hydrogen peroxide (H2O2) with the linear dynamic range of 2.0-225.0 muM. Hydrogen Peroxide 104-121 latexin Homo sapiens 172-175 23787095-7 2013 Moreover, the resulting electrode exhibited excellent electrocatalytic ability towards the reduction of hydrogen peroxide (H2O2) with the linear dynamic range of 2.0-225.0 muM. Hydrogen Peroxide 123-127 latexin Homo sapiens 172-175 23712505-5 2013 SIPS was established by exposure to H2 O2 at a subcytotoxic concentration of 20 muM for two weeks. Hydrogen Peroxide 36-41 latexin Homo sapiens 80-83 23868495-5 2013 As a proof-of-concept demonstration, we investigate its use in high-performance supercapacitors (~392 F g(-1)), and for sensitive detection of H2O2 (with a low detection limit of ~0.1 muM) and methanol (with a low detection limit of ~60 muM). Hydrogen Peroxide 143-147 latexin Homo sapiens 184-187 23817786-6 2013 Relative CL intensity is linearly related to the concentration of H2O2 in the range from 0.01 to 50 muM. Hydrogen Peroxide 66-70 latexin Homo sapiens 100-103 24090008-6 2013 Antioxidant activity was evaluated through exposing the cells to sub-lethal extract concentrations for 24 hours and then to oxidative stress induced by 60 muM arachidonic acid and 50 muM H2O2. Hydrogen Peroxide 187-191 latexin Homo sapiens 183-186 32261076-6 2013 Under an optimal experimental condition, the created biosensor for detecting hydrogen peroxide has a sensitivity of 160.6 muA mM-1 cm-2, a wide linear range from 0.5 to 30 mM and a detection limit of 18.6 muM (S/N = 3), which indicates that this novel and simple strategy for fabricating electrochemical sensor by an electrospinning technique has wide potential applications in bio-analysis and detection. Hydrogen Peroxide 77-94 latexin Homo sapiens 205-208 32260935-7 2013 The detection limit was estimated to be 0.6 muM at a signal/noise (S/N) ratio of 3, and the linear range of H2O2 concentration was from 1 muM to 1100 muM. Hydrogen Peroxide 108-112 latexin Homo sapiens 138-141 32260935-7 2013 The detection limit was estimated to be 0.6 muM at a signal/noise (S/N) ratio of 3, and the linear range of H2O2 concentration was from 1 muM to 1100 muM. Hydrogen Peroxide 108-112 latexin Homo sapiens 138-141 23333646-8 2013 A linear increase in the catalytic current is observed for the reduction of hydrogen peroxide in the concentration range from 1 to 20 muM, with a detection limit of 0.4 muM. Hydrogen Peroxide 76-93 latexin Homo sapiens 134-137 23333646-8 2013 A linear increase in the catalytic current is observed for the reduction of hydrogen peroxide in the concentration range from 1 to 20 muM, with a detection limit of 0.4 muM. Hydrogen Peroxide 76-93 latexin Homo sapiens 169-172 23154514-6 2013 Under the optimized conditions, the H(2)O(2) sensor exhibited a low detection limit down to 33.9 nM with a wide linear range from 0.05 to 1000 muM. Hydrogen Peroxide 36-44 latexin Homo sapiens 143-146 32260780-11 2013 Its electrochemical response shows the linear dependence of hydrogen peroxide concentration in a range between 10 muM and 80 muM with a detection limit of 0.1 muM. Hydrogen Peroxide 60-77 latexin Homo sapiens 114-117 32260780-11 2013 Its electrochemical response shows the linear dependence of hydrogen peroxide concentration in a range between 10 muM and 80 muM with a detection limit of 0.1 muM. Hydrogen Peroxide 60-77 latexin Homo sapiens 125-128 32260780-11 2013 Its electrochemical response shows the linear dependence of hydrogen peroxide concentration in a range between 10 muM and 80 muM with a detection limit of 0.1 muM. Hydrogen Peroxide 60-77 latexin Homo sapiens 125-128 23313413-1 2013 At optimal NADH concentration (50muM), the complex I-mediated process results in a formation of two superoxide anions and H(2)O(2) as the reaction products in approximately 0.7 ratio. Hydrogen Peroxide 122-130 latexin Homo sapiens 33-36 23849871-5 2013 By varying the glucose oxidase concentration in the medium, target ranges of steady-state H2O2 concentrations (30-90 muM) can be attained for up to 6h, with subsequent assessment of cellular signaling and glucose transport activity. Hydrogen Peroxide 90-94 latexin Homo sapiens 117-120 21645672-3 2011 The PB-graphene/GCE showed sensitive response to H(2)O(2) with a wide linear range of 10-1440 muM at 0.0V, and to hydrazine with a wide linear range of 10-3000 muM at 0.35 V. The detection limit was 3 muM and 7 muM, respectively, and both of them had rapid response within 5s to reach 95% steady state response. Hydrogen Peroxide 49-57 latexin Homo sapiens 94-97 22949159-5 2012 Additionally, electrochemical pretreatment of platinum working electrodes aiming at surface oxidation improves the limit of detection of the sensor and the linearity of the calibration curve at low H2O2 concentrations (<10 muM). Hydrogen Peroxide 198-202 latexin Homo sapiens 226-229 25683399-6 2012 Using siRNA to knock down TrxR-1 or Nrf2, sulforaphane (5 muM)-protected cell viability was reduced from 73% to 46% and 34%, respectively, suggesting that TrxR-1 is an important enzyme in protection against hydrogen peroxide-induced cell death. Hydrogen Peroxide 207-224 latexin Homo sapiens 58-61 21663493-4 2011 METHODS: Human retinal D407 RPE cells were pretreated with resveratrol at 3 different concentrations (25, 50, and 100 muM) for 24 h and exposed for 1 h to 500 muM hydrogen peroxide. Hydrogen Peroxide 163-180 latexin Homo sapiens 159-162 25486783-8 2013 While a sub-lethal H2O2 dose (200 muM) promoted in hMESC only SIPS, the higher H2O2 doses induced also apoptosis in the part of the cell population. Hydrogen Peroxide 19-23 latexin Homo sapiens 34-37 25486783-9 2013 On the contrary, in hESC, H2O2 regardless of the doses tested (from 50 to 500 muM) triggered apoptosis, that was the only pronounced response of these cells to oxidative damage. Hydrogen Peroxide 26-30 latexin Homo sapiens 78-81 22716478-6 2012 Amperometric determination of H2O2 at -0.55 V gave a limit of detection of 1.6 muM (S / N = 3) and a sensitivity of 19.29 mA cm-2 M-1 up to 6 mM, with a response time (steady state, t95) of 30 to 40 s. Energy dispersive X-ray analysis, transmission electron microscopic image, cyclic voltammetry (CV), and scanning electron microscopic images were utilized to characterize the modified electrode. Hydrogen Peroxide 30-34 latexin Homo sapiens 79-82 22200560-10 2012 Melatonin also has significant neuroprotective effects, reversing the inhibition of neuritogenesis by 200 and 500 muM hydrogen peroxide. Hydrogen Peroxide 118-135 latexin Homo sapiens 114-117 22276528-6 2012 This reagentless biosensing approach was capable of detecting H(2)O(2), a simple molecule but plays an important role in analytical and biological chemistry, as low as 0.1 muM with linearity of 0.1-60 muM and a response time of <0.8 s, comparing favorably with other carbon based electrodes (5 s). Hydrogen Peroxide 62-70 latexin Homo sapiens 172-175 22276528-6 2012 This reagentless biosensing approach was capable of detecting H(2)O(2), a simple molecule but plays an important role in analytical and biological chemistry, as low as 0.1 muM with linearity of 0.1-60 muM and a response time of <0.8 s, comparing favorably with other carbon based electrodes (5 s). Hydrogen Peroxide 62-70 latexin Homo sapiens 201-204 22138566-2 2012 We evaluated DNA damage induced by treatment with hydrogen peroxide (H(2)O(2); 5, 25 and 50muM) and methyl methane sulfonate (MMS; 5, 25 and 50muM) in both human B- and T-lymphocytes obtained by MACS, and compared their DNA damage levels. Hydrogen Peroxide 50-67 latexin Homo sapiens 91-94 22002943-11 2012 For all assays performed with 33 muM Mn(2+), the initial rate of the decolorization process was found to be dependent on the dosage of H(2)O(2). Hydrogen Peroxide 135-143 latexin Homo sapiens 33-36 21075044-1 2011 Redox cycling compounds (RCCs) generate muM concentrations of hydrogen peroxide (H(2)O(2)) in the presence of strong reducing agents, common buffer components used to maintain the catalytic activity and/or folding of target proteins for high throughput screening (HTS) assays. Hydrogen Peroxide 62-79 latexin Homo sapiens 40-43 21172384-6 2011 In vitro, 250 muM H2O2 was treated to SH-SY5Y cells after the pre-treatment of SP-8203 (2, 20 and 200 muM). Hydrogen Peroxide 18-22 latexin Homo sapiens 14-17 21172384-6 2011 In vitro, 250 muM H2O2 was treated to SH-SY5Y cells after the pre-treatment of SP-8203 (2, 20 and 200 muM). Hydrogen Peroxide 18-22 latexin Homo sapiens 102-105 21595444-4 2011 Moreover, release of cargo has been enzymatically driven by oxidoreductase enzymes such as chloroperoxidase and myeloperoxidase in the presence of low concentrations of sodium chloride (200 mM) and hydrogen peroxide (500 muM). Hydrogen Peroxide 198-215 latexin Homo sapiens 221-224 21286651-3 2011 In the Cu(I)/H(2)O(2) system, selenocystine, selenomethionine, and methyl-selenocysteine inhibit DNA damage with IC(50) values ranging from 3.34 to 25.1 muM. Hydrogen Peroxide 13-21 latexin Homo sapiens 153-156 21047171-4 2011 When cells were challenged with hydrogen peroxide (H(2)O(2)), following mitoQ treatment (0.1-1.0 muM), the ratio of reduced to oxidized forms of glutathione increased, the levels of oxidative DNA damage decreased and there was an increase in the mitochondrial membrane potential. Hydrogen Peroxide 32-49 latexin Homo sapiens 97-100 21255447-5 2011 Cell death of nef-expressing astrocytes exposed to 10 muM hydrogen peroxide for 30 min occurred within 4 h. CONCLUSION: HIV-1 Nef may contribute to neuronal dysfunction and the development of HAD by causing death of astrocytes through decreasing their tolerance for hydrogen peroxide. Hydrogen Peroxide 58-75 latexin Homo sapiens 54-57 21255447-5 2011 Cell death of nef-expressing astrocytes exposed to 10 muM hydrogen peroxide for 30 min occurred within 4 h. CONCLUSION: HIV-1 Nef may contribute to neuronal dysfunction and the development of HAD by causing death of astrocytes through decreasing their tolerance for hydrogen peroxide. Hydrogen Peroxide 266-283 latexin Homo sapiens 54-57 21063685-10 2011 L-NBP treatment at dose of 10 muM inhibited H2O2-induced down-regulation of Bcl-2, Bcl-w, and PKCalpha but also attenuated the overexpression of Bax. Hydrogen Peroxide 44-48 latexin Homo sapiens 30-33 21111806-9 2011 Inhibition occurred at hydroperoxide concentrations of >=1muM for oxidized amino acids and peptides and >=10muM for oxidized proteins, compared with ca. Hydrogen Peroxide 23-36 latexin Homo sapiens 61-64 21215240-3 2010 Using the MTT reduction assay and Calcein-AM staining assay, we showed that pretreatment with H2O2 (10 muM, 24 hr) of COS7 cells partially protected cells against subsequent H2O2 (6 mM, 1 hr) - induced cytotoxicity. Hydrogen Peroxide 94-98 latexin Homo sapiens 103-106 20921226-4 2010 Indeed, we found that high concentrations of hydroperoxide activator (e.g. 65 muM) overcame a prolonged lag phase (>1 h) and unveiled a dioxygenase activity with arachidonic acid; the main products were the 5-, 9-, and 7-hydroperoxyeicosatetraenoic acids (HPETEs). Hydrogen Peroxide 45-58 latexin Homo sapiens 78-81 21215240-3 2010 Using the MTT reduction assay and Calcein-AM staining assay, we showed that pretreatment with H2O2 (10 muM, 24 hr) of COS7 cells partially protected cells against subsequent H2O2 (6 mM, 1 hr) - induced cytotoxicity. Hydrogen Peroxide 174-178 latexin Homo sapiens 103-106 21215240-4 2010 The phosphorylation of Akt/PKB, a downstream target of phosphatydylinositol-3 kinase (PI3K), at Ser473 was augmented by H2O2 (10 muM) administration. Hydrogen Peroxide 120-124 latexin Homo sapiens 129-132 21215240-5 2010 This augmentation peaked at 10 minutes after H2O2 (10 muM) treatment and fell to the basal level at 24 hr. Hydrogen Peroxide 45-49 latexin Homo sapiens 54-57 21215240-6 2010 A blocker of PI3K, LY294002, significantly attenuated H2O2 (10 muM, 24 hr) - induced cytoprotection. Hydrogen Peroxide 54-58 latexin Homo sapiens 63-66 21215240-7 2010 In addition, pretreatment with LY294002 reduced H2O2 (10 muM, 10 min)-induced phosphorylation of Akt at Ser473. Hydrogen Peroxide 48-52 latexin Homo sapiens 57-60 23105852-4 2009 Hydrogen peroxide was studied at 50, 100 and 200muM and was found to increase a dose dependent increase in lipid peroxidation and micronuclei frequency. Hydrogen Peroxide 0-17 latexin Homo sapiens 48-51 19100530-5 2010 Oxidative stress was induced by hydrogen peroxide (H(2)O(2), 100 muM). Hydrogen Peroxide 32-49 latexin Homo sapiens 65-68 20832166-4 2010 In addition, the TOC removal efficiencies of the alachlor under initial H(2)O(2) concentrations of 0, 0.5 and 1.0 muM were 59.5, 74.8 and 83.8%, respectively, at an absorbed dose of 20 k Gy. Hydrogen Peroxide 72-80 latexin Homo sapiens 114-117 20869113-3 2010 We found that TRH and all the tested analogues at concentrations 0.1-50 muM attenuated cell damage induced by MPP(+) (2 mM), 3-nitropropionate (10 mM), hydrogen peroxide (0.5 mM), homocysteine (250 muM) and beta-amyloid (20muM) in retinoic acid differentiated SH-SY5Y cells. Hydrogen Peroxide 152-169 latexin Homo sapiens 72-75 21030031-7 2010 The limit of detection for hydrogen peroxide was 6 muM by HPLC/FD, and 0.6 muM by HPLC/ED. Hydrogen Peroxide 27-44 latexin Homo sapiens 51-54 20815781-2 2010 Hydrogen peroxide (15 muM) and taurine chloramine (200 muM) induced HL 60 differentiation, which was detected by CD11b expression and superoxide production. Hydrogen Peroxide 0-17 latexin Homo sapiens 22-25 20815781-2 2010 Hydrogen peroxide (15 muM) and taurine chloramine (200 muM) induced HL 60 differentiation, which was detected by CD11b expression and superoxide production. Hydrogen Peroxide 0-17 latexin Homo sapiens 55-58 24301826-4 1996 15% of the total cyt b-559 could be transiently oxidised by 200 muM H2O2 in the dark. Hydrogen Peroxide 68-72 latexin Homo sapiens 64-67 20021146-7 2004 Interference with the detection of H(2)O(2)-induced DNA strand breaks appears to be SM concentration-dependent up to 30 muM, and independent of SM concentration at >/=30 muM. Hydrogen Peroxide 35-43 latexin Homo sapiens 120-123 20021146-7 2004 Interference with the detection of H(2)O(2)-induced DNA strand breaks appears to be SM concentration-dependent up to 30 muM, and independent of SM concentration at >/=30 muM. Hydrogen Peroxide 35-43 latexin Homo sapiens 173-176 21043868-1 1992 Hydrogen peroxide (H(2)O(2)) triggers activation of platelets "primed" by low concentrations of arachidonic acid (< 20 muM) or collagen (< 0.2 mug/ml), but has no effect on platelets exposed to low concentrations of thrombin, ADP or A23187. Hydrogen Peroxide 0-17 latexin Homo sapiens 122-125 27405834-7 1995 Low concentration of ebselen (5 muM) plus GSH (50 muM) decomposed hydroperoxides in pre-oxidized LDL whether EDTA was added or not. Hydrogen Peroxide 66-80 latexin Homo sapiens 32-35 27405834-7 1995 Low concentration of ebselen (5 muM) plus GSH (50 muM) decomposed hydroperoxides in pre-oxidized LDL whether EDTA was added or not. Hydrogen Peroxide 66-80 latexin Homo sapiens 50-53 21043622-5 1995 Treatment of endothelial cells with hydrogen peroxide also induced endothelial cell injury in a dose dependent manner (50-150 muM). Hydrogen Peroxide 36-53 latexin Homo sapiens 126-129 21043622-6 1995 Dipyridamole also prevented the endothelial cell injury induced by hydrogen peroxide with a dose dependent fashion (1-10 muM). Hydrogen Peroxide 67-84 latexin Homo sapiens 121-124