PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12054657-2 2002 In this report, we demonstrate for the first time that endogenous Bruton"s tyrosine kinase (Btk) and Akt can interact with each other in DT40 chicken B cells and human Nalm6 B cells and that this interaction is inducible following H2O2 stimulation. Hydrogen Peroxide 231-235 Bruton tyrosine kinase Gallus gallus 66-90 12054657-2 2002 In this report, we demonstrate for the first time that endogenous Bruton"s tyrosine kinase (Btk) and Akt can interact with each other in DT40 chicken B cells and human Nalm6 B cells and that this interaction is inducible following H2O2 stimulation. Hydrogen Peroxide 231-235 Bruton tyrosine kinase Gallus gallus 92-95 11434777-2 2001 Our genetic evidence showed that Btk deficiency resulted in a significant reduction in hydrogen peroxide-induced calcium response. Hydrogen Peroxide 87-104 Bruton tyrosine kinase Gallus gallus 33-36 11434777-5 2001 The data from the point mutation study revealed that a defect at any one of the three functional domains would prevent a full recovery of Btk-mediated hydrogen peroxide-induced intracellular calcium mobilization. Hydrogen Peroxide 151-168 Bruton tyrosine kinase Gallus gallus 138-141