PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11360926-8	2001	These data are consistent with previous results that 5-HT modulates NKCA via 5-HT1A receptors on monocytes and suggest that 5-HT may abrogate monocyte suppression of NKCA by inhibiting monocyte signals such as H2O2.	Hydrogen Peroxide	210-214	5-hydroxytryptamine receptor 1A	Homo sapiens	77-83	
12676358-2	2003	Two 5-HT(1A) agonists, Repinotan hydrochloride (BAY x 3702) and 8-OH-DPAT, block caspase-3 activation and apoptosis caused by anoxia/reoxygenation and H(2)O(2) treatment.	Hydrogen Peroxide	151-159	5-hydroxytryptamine receptor 1A	Homo sapiens	4-11	
12676358-7	2003	Finally, transient expression of kinase-negative PKCalpha eliminated the 8-OH-DPAT-evoked block on the H(2)O(2)-triggered caspase-3 stimulation, establishing PKCalpha as a link between ERK and caspase-3 (5-HT(1A)-R-->PLC-->ERK1/2-->PKCalpha-->caspase-3).	Hydrogen Peroxide	103-111	5-hydroxytryptamine receptor 1A	Homo sapiens	204-211	
33178009-10	2020	However, it exerted an inhibitive effect on the overexpressed mRNA of GABRA1, GABRA2, HTR1A, and HTR2A in H2O2 treated SH-SY5Y cells.	Hydrogen Peroxide	106-110	5-hydroxytryptamine receptor 1A	Homo sapiens	86-91	
10727402-5	2000	(3) The 5-HT(1A) receptor alters cellular redox properties, and generates both superoxide and hydrogen peroxide.	Hydrogen Peroxide	94-111	5-hydroxytryptamine receptor 1A	Homo sapiens	8-25	
10727402-9	2000	Moreover, these experiments provide confirmation that the transfected human 5-HT(1A) receptor induces the production of ROS (superoxide and hydrogen peroxide) in CHO cells, and support the possibility that an NAD(P)H oxidase-like enzyme might be involved in the 5-HT-mediated generation of both superoxide and hydrogen peroxide.	Hydrogen Peroxide	140-157	5-hydroxytryptamine receptor 1A	Homo sapiens	76-93	
10727402-9	2000	Moreover, these experiments provide confirmation that the transfected human 5-HT(1A) receptor induces the production of ROS (superoxide and hydrogen peroxide) in CHO cells, and support the possibility that an NAD(P)H oxidase-like enzyme might be involved in the 5-HT-mediated generation of both superoxide and hydrogen peroxide.	Hydrogen Peroxide	310-327	5-hydroxytryptamine receptor 1A	Homo sapiens	76-93