PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32702479-5 2020 The present findings show that heat shock increases NADPH oxidase 2 mRNA levels and hydrogen peroxide produced by snail hemocytes, and that both of these phenotypes could be reversed by an HSP-90 inhibitor. Hydrogen Peroxide 84-101 snail family transcriptional repressor 1 Homo sapiens 114-119 27613835-3 2016 Hydrogen peroxide treatment induced EMT features such as elevation of vimentin and Snail with a corresponding reduction of E-cadherin. Hydrogen Peroxide 0-17 snail family transcriptional repressor 1 Homo sapiens 83-88 32132577-4 2020 Hydrogen peroxide (H2O2) not only upregulated alpha-SMA but also enhanced the effect of TGF-beta2 on the expression of Snail and Slug. Hydrogen Peroxide 0-17 snail family transcriptional repressor 1 Homo sapiens 119-124 32132577-4 2020 Hydrogen peroxide (H2O2) not only upregulated alpha-SMA but also enhanced the effect of TGF-beta2 on the expression of Snail and Slug. Hydrogen Peroxide 19-23 snail family transcriptional repressor 1 Homo sapiens 119-124 30954555-0 2019 Epigenetic silencing of genes enhanced by collective role of reactive oxygen species and MAPK signaling downstream ERK/Snail axis: Ectopic application of hydrogen peroxide repress CDH1 gene by enhanced DNA methyltransferase activity in human breast cancer. Hydrogen Peroxide 154-171 snail family transcriptional repressor 1 Homo sapiens 119-124 30954555-5 2019 Sublethal dosage of H2O2 treatment decrease E-cadherin, increase DNMT1, HDAC1, Snail, Slug and enrich H3K9me3 and H3K27me3 in the CDH1 promoter. Hydrogen Peroxide 20-24 snail family transcriptional repressor 1 Homo sapiens 79-84 22580338-0 2012 Manganese superoxide dismutase induces migration and invasion of tongue squamous cell carcinoma via H2O2-dependent Snail signaling. Hydrogen Peroxide 100-104 snail family transcriptional repressor 1 Homo sapiens 115-120 22580338-7 2012 Thus, we conclude that the SOD2-dependent production of H(2)O(2) contributes to both the migration and the invasion of TSCC via the Snail signaling pathway, through increased Snail, MMP1, and pERK1/2 protein levels and the repression of the E-cadherin protein. Hydrogen Peroxide 56-64 snail family transcriptional repressor 1 Homo sapiens 132-137 22580338-7 2012 Thus, we conclude that the SOD2-dependent production of H(2)O(2) contributes to both the migration and the invasion of TSCC via the Snail signaling pathway, through increased Snail, MMP1, and pERK1/2 protein levels and the repression of the E-cadherin protein. Hydrogen Peroxide 56-64 snail family transcriptional repressor 1 Homo sapiens 175-180 21093414-4 2011 Moreover, Snail-expressing cells displayed increased concentration of reactive oxygen species (ROS), specifically, superoxide and hydrogen peroxide, in vitro and in vivo. Hydrogen Peroxide 130-147 snail family transcriptional repressor 1 Homo sapiens 10-15 20610539-0 2010 Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells. Hydrogen Peroxide 0-17 snail family transcriptional repressor 1 Homo sapiens 97-102 17350594-0 2007 Stabilization of Snail by HuR in the process of hydrogen peroxide induced cell migration. Hydrogen Peroxide 48-65 snail family transcriptional repressor 1 Homo sapiens 17-22 17350594-3 2007 Here, we have observed increased expression of Snail under the treatment of hydrogen peroxide (H(2)O(2)). Hydrogen Peroxide 76-93 snail family transcriptional repressor 1 Homo sapiens 47-52 17350594-8 2007 Our findings indicate that HuR plays a major role in regulating H(2)O(2)-induced Snail expression by enhancing Snail mRNA stability, which in turn enhances cell migrating ability through repressing expression of E-cadherin. Hydrogen Peroxide 64-72 snail family transcriptional repressor 1 Homo sapiens 81-86 17350594-8 2007 Our findings indicate that HuR plays a major role in regulating H(2)O(2)-induced Snail expression by enhancing Snail mRNA stability, which in turn enhances cell migrating ability through repressing expression of E-cadherin. Hydrogen Peroxide 64-72 snail family transcriptional repressor 1 Homo sapiens 111-116