PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6433574-2	1983	The hydrogen peroxide released from M. pneumoniae was responsible for the induction of IFN from lymphocytes, since horseradish peroxidase inhibited the IFN production and abrogated the activity of IFN production in the supernatant of M. pneumoniae.	Hydrogen Peroxide	4-21	interferon alpha 1	Homo sapiens	87-90	
2965208-5	1988	Unexpectedly, low concentrations of IFN-alpha or -beta (3 fM-300 pM) blocked induction of H2O2-releasing capacity by rIFN-gamma (10 pM), with a 50% inhibitory dose of approximately 80 fM.	Hydrogen Peroxide	90-94	interferon alpha 1	Homo sapiens	36-45	
3919096-1	1985	Interferon (IFN)-inducing activity of hydrogen peroxide in human peripheral mononuclear cells was investigated.	Hydrogen Peroxide	38-55	interferon alpha 1	Homo sapiens	0-10	
3919096-1	1985	Interferon (IFN)-inducing activity of hydrogen peroxide in human peripheral mononuclear cells was investigated.	Hydrogen Peroxide	38-55	interferon alpha 1	Homo sapiens	12-15	
3919096-3	1985	The maximal titer of IFN by purified nonadherent cells was observed after a 72-hr cultivation in the presence of 10(-2) mM H2O2 without affecting their viability.	Hydrogen Peroxide	123-127	interferon alpha 1	Homo sapiens	21-24	
3919096-6	1985	The NK-enriched low density fractions, but not the T cell-enriched high density fractions, showed IFN production by the stimulation of hydrogen peroxide.	Hydrogen Peroxide	135-152	interferon alpha 1	Homo sapiens	98-101	
3919096-8	1985	Moreover, hydrogen peroxide-inducing IFN production seems to be regulated by monocytes.	Hydrogen Peroxide	10-27	interferon alpha 1	Homo sapiens	37-40	
6433574-2	1983	The hydrogen peroxide released from M. pneumoniae was responsible for the induction of IFN from lymphocytes, since horseradish peroxidase inhibited the IFN production and abrogated the activity of IFN production in the supernatant of M. pneumoniae.	Hydrogen Peroxide	4-21	interferon alpha 1	Homo sapiens	152-155	
6433574-2	1983	The hydrogen peroxide released from M. pneumoniae was responsible for the induction of IFN from lymphocytes, since horseradish peroxidase inhibited the IFN production and abrogated the activity of IFN production in the supernatant of M. pneumoniae.	Hydrogen Peroxide	4-21	interferon alpha 1	Homo sapiens	152-155	
16595158-2	2006	METHODS: We examined in a human hepatocellular carcinoma cell line (Huh-7) the effect of hydrogen peroxide (H2O2), as a generator of oxidative stress, on the IFN-alpha signaling pathway.	Hydrogen Peroxide	89-106	interferon alpha 1	Homo sapiens	158-167	
16595158-2	2006	METHODS: We examined in a human hepatocellular carcinoma cell line (Huh-7) the effect of hydrogen peroxide (H2O2), as a generator of oxidative stress, on the IFN-alpha signaling pathway.	Hydrogen Peroxide	108-112	interferon alpha 1	Homo sapiens	158-167	
16595158-3	2006	RESULTS: Pretreatment of Huh-7 cells with 0.5-1 mM H2O2 resulted in the suppression of the IFN-alpha-induced antiviral protein MxA and of IRF-9 mRNA expression.	Hydrogen Peroxide	51-55	interferon alpha 1	Homo sapiens	91-100	
16595158-4	2006	The reduced expression of these genes was associated to H2O2 -mediated suppression of the IFN-alpha-induced assembly of signal transducer and activator of transcription (STAT) factors to specific promoter motifs on IFN-alpha-inducible genes.	Hydrogen Peroxide	56-60	interferon alpha 1	Homo sapiens	90-99	
16595158-4	2006	The reduced expression of these genes was associated to H2O2 -mediated suppression of the IFN-alpha-induced assembly of signal transducer and activator of transcription (STAT) factors to specific promoter motifs on IFN-alpha-inducible genes.	Hydrogen Peroxide	56-60	interferon alpha 1	Homo sapiens	215-224	
2114820-4	1990	Three of the four cytokine preparations (Il-4, TNF and IFN-alpha/beta), however, increased the macrophages capacity to secrete H2O2 in response to either immune complex or PMA, IFN-gamma alone did not affect H2O2 secretion.	Hydrogen Peroxide	127-131	interferon alpha 1	Homo sapiens	55-64