PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32579217-6	2020	In vitro, hepatocyte injury triggered the increase of Sox9/H19 axis, whereas silence of H19 greatly alleviated the H2O2-induced hepatocyte apoptosis, suggesting that H19 functions as a downstream effector of Sox9 signaling and is involved in hepatocyte apoptosis.	Hydrogen Peroxide	115-119	H19 imprinted maternally expressed transcript	Homo sapiens	88-91	
32579217-6	2020	In vitro, hepatocyte injury triggered the increase of Sox9/H19 axis, whereas silence of H19 greatly alleviated the H2O2-induced hepatocyte apoptosis, suggesting that H19 functions as a downstream effector of Sox9 signaling and is involved in hepatocyte apoptosis.	Hydrogen Peroxide	115-119	H19 imprinted maternally expressed transcript	Homo sapiens	88-91	
30323617-11	2018	Addition of H2O2 to induce oxidative stress largely reversed TMZ sensitivity caused by H19 knockdown.	Hydrogen Peroxide	12-16	H19 imprinted maternally expressed transcript	Homo sapiens	87-90	
29520849-0	2018	LncRNA H19 targets miR-22 to modulate H2 O2 -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling.	Hydrogen Peroxide	38-43	H19 imprinted maternally expressed transcript	Homo sapiens	7-10	
29520849-4	2018	Herein, we investigated the detailed function and mechanism of H19, one of the most up-regulated lncRNAs in IDD specimens, in H2 O2 -induced cell senescence model in NPCs.	Hydrogen Peroxide	126-131	H19 imprinted maternally expressed transcript	Homo sapiens	63-66	
29520849-5	2018	H19 could accelerate H2 O2 -induced degenerative changes by promoting cell senescence, increasing ADAMTS-5 and MMPs protein levels and Collagen I content, as well as suppressing NPC proliferation through activating Wnt/beta-catenin signaling.	Hydrogen Peroxide	21-26	H19 imprinted maternally expressed transcript	Homo sapiens	0-3	
29520849-7	2018	Taken together, H19 acts as a ceRNA to compete with LEF1 for miR-22, thus modulating downstream Wnt/beta-catenin signaling in NPCs; H19/miR-22/LEF1 might be a novel target for improving H2 O2 -induced NPC senescence and treatment for IDD.	Hydrogen Peroxide	186-191	H19 imprinted maternally expressed transcript	Homo sapiens	16-19	
29520849-7	2018	Taken together, H19 acts as a ceRNA to compete with LEF1 for miR-22, thus modulating downstream Wnt/beta-catenin signaling in NPCs; H19/miR-22/LEF1 might be a novel target for improving H2 O2 -induced NPC senescence and treatment for IDD.	Hydrogen Peroxide	186-191	H19 imprinted maternally expressed transcript	Homo sapiens	132-135	
27809873-7	2016	We identified that two lncRNAs, H19 and HULC, were differentially expressed among all the samples under the treatment of hypoxic or inflammatory factors, and they were shown to be stimulated by short-term oxidative stress responses to H2O2 and glucose oxidase in CCA cell lines.	Hydrogen Peroxide	235-239	H19 imprinted maternally expressed transcript	Homo sapiens	32-35	
27062045-8	2016	Interestingly, we found that long noncoding RNA H19 and its derived miR-675 were downregulated by H2 O2 in CPCs, but melatonin treatment could counter this alteration.	Hydrogen Peroxide	98-103	H19 imprinted maternally expressed transcript	Homo sapiens	48-51	
27062045-9	2016	Furthermore, knockdown of H19 or miR-675 blocked antisenescence actions of melatonin on H2 O2 -treated CPCs.	Hydrogen Peroxide	88-93	H19 imprinted maternally expressed transcript	Homo sapiens	26-29	
27193186-8	2016	Furthermore, H19-knockdown cells were markedly more sensitive to hydrogen-peroxide treatment and exhibited lower glutathione levels.	Hydrogen Peroxide	65-82	H19 imprinted maternally expressed transcript	Homo sapiens	13-16