PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11169101-1 2001 The Saccharomyces cerevisiae Yap1p transcription factor is required for the H2O2-dependent activation of many antioxidant genes including the TRX2 gene encoding thioredoxin 2. Hydrogen Peroxide 76-80 thioredoxin TRX2 Saccharomyces cerevisiae S288C 142-146 16219769-9 2005 In this work, we demonstrate that the proper folding of Yap1p in the presence of H(2)O(2) is required for recruitment of the mediator component Rox3p to the TRX2 promoter in addition to the nuclear accumulation of Yap1p during stress by this oxidant. Hydrogen Peroxide 81-89 thioredoxin TRX2 Saccharomyces cerevisiae S288C 157-161 11929546-5 2002 First, the trx1 and trx2 mutants show wild-type resistance to hydroperoxide during exponential phase growth; secondly, overexpression of either TRX1 or TRX2 leads to increased resistance to hydroperoxides; and, thirdly, both Trx1 and Trx2 are equally able to act as cofactors for the thioredoxin peroxidase, Tsa1. Hydrogen Peroxide 62-75 thioredoxin TRX2 Saccharomyces cerevisiae S288C 20-24 11929546-5 2002 First, the trx1 and trx2 mutants show wild-type resistance to hydroperoxide during exponential phase growth; secondly, overexpression of either TRX1 or TRX2 leads to increased resistance to hydroperoxides; and, thirdly, both Trx1 and Trx2 are equally able to act as cofactors for the thioredoxin peroxidase, Tsa1. Hydrogen Peroxide 62-75 thioredoxin TRX2 Saccharomyces cerevisiae S288C 152-156 11929546-5 2002 First, the trx1 and trx2 mutants show wild-type resistance to hydroperoxide during exponential phase growth; secondly, overexpression of either TRX1 or TRX2 leads to increased resistance to hydroperoxides; and, thirdly, both Trx1 and Trx2 are equally able to act as cofactors for the thioredoxin peroxidase, Tsa1. Hydrogen Peroxide 190-204 thioredoxin TRX2 Saccharomyces cerevisiae S288C 20-24 11929546-5 2002 First, the trx1 and trx2 mutants show wild-type resistance to hydroperoxide during exponential phase growth; secondly, overexpression of either TRX1 or TRX2 leads to increased resistance to hydroperoxides; and, thirdly, both Trx1 and Trx2 are equally able to act as cofactors for the thioredoxin peroxidase, Tsa1. Hydrogen Peroxide 190-204 thioredoxin TRX2 Saccharomyces cerevisiae S288C 152-156 7881546-6 1994 Furthermore, induction of the yeast H2O2-responsive TRX2 promoter by menadione required the metabolism of menadione. Hydrogen Peroxide 36-40 thioredoxin TRX2 Saccharomyces cerevisiae S288C 52-56 8313910-0 1994 YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. Hydrogen Peroxide 115-129 thioredoxin TRX2 Saccharomyces cerevisiae S288C 29-33 8313910-5 1994 Using a specific genetic screen, the TRX2 gene, one of two genes of S. cerevisiae that encode thioredoxin protein, was identified as being essential for YAP1 dependent resistance to hydroperoxides. Hydrogen Peroxide 182-196 thioredoxin TRX2 Saccharomyces cerevisiae S288C 37-41 12743123-2 2003 Ybp1 is required for H2O2-induced expression of the antioxidant encoding gene TRX2. Hydrogen Peroxide 21-25 thioredoxin TRX2 Saccharomyces cerevisiae S288C 78-82