PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30293571-7	2018	Moreover, mobilization and increased activation of TRPC6 by suPAR or H2O2 was blocked by concurrent exposure to PP2, an inhibitor of Src family tyrosine kinases.	Hydrogen Peroxide	69-73	neuropeptide Y receptor Y6	Mus musculus	112-115	
12237126-4	2002	Immunoprecipitated CHC showed tyrosine phosphorylation upon H(2)O(2) treatment and the phosphorylation was suppressed by the Src kinase inhibitor, PP2.	Hydrogen Peroxide	60-68	neuropeptide Y receptor Y6	Mus musculus	147-150	
10766791-5	2000	First, the specific Src family tyrosine kinase inhibitor, PP2, inhibited JNK activation by H(2)O(2) in a concentration-dependent manner but had no effect on extracellular signal-regulated kinases 1 and 2 and p38 activation.	Hydrogen Peroxide	91-99	neuropeptide Y receptor Y6	Mus musculus	58-61	
18854310-9	2008	PP2, a Fyn-specific inhibitor, blocked JAK2, STAT3, and p38 MAPK activation and significantly attenuated apoptosis induced by H(2)O(2).	Hydrogen Peroxide	126-134	neuropeptide Y receptor Y6	Mus musculus	0-3	
16914136-7	2006	The release induced by PMA/A23187 and by H(2)O(2)/A23187 was significantly inhibited by a PKC inhibitor (10 microM GF109203X) and in PKC-depleted cells, and by a Src inhibitor (2 microM PP2).	Hydrogen Peroxide	41-49	neuropeptide Y receptor Y6	Mus musculus	186-189	
15356004-0	2004	Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2.	Hydrogen Peroxide	136-140	neuropeptide Y receptor Y6	Mus musculus	30-33	
15356004-7	2004	In this study we have demonstrated that PP2 (4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine), a potent and selective inhibitor of the Src-family tyrosine kinase, greatly potentiated the ability of PMA and/or H2O2 to activate Raf-1 kinase, whereas it blocked the tyrosine phosphorylation of Raf-1.	Hydrogen Peroxide	225-229	neuropeptide Y receptor Y6	Mus musculus	40-43	
15356004-14	2004	This PP2 effect resulted in significant and sustained Ras-independent activation of Raf-1 by PMA and H2O2.	Hydrogen Peroxide	101-105	neuropeptide Y receptor Y6	Mus musculus	5-8