PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23394834-3	2013	The H2O2 signal is generated by activation of an NADPH oxidase, DUOX, and as a consequence, the first inflammatory cells are recruited to the wound within minutes.	Hydrogen Peroxide	4-8	Dual oxidase	Drosophila melanogaster	64-68	
31575764-3	2019	Generation of hydrogen peroxide (H2O2) by the dual oxidase (Duox) pathway is a critical component of the innate immune response, which functions to impede infection and maintain homeostatic regulation of the gut microbiota.	Hydrogen Peroxide	14-31	Dual oxidase	Drosophila melanogaster	46-58	
31575764-3	2019	Generation of hydrogen peroxide (H2O2) by the dual oxidase (Duox) pathway is a critical component of the innate immune response, which functions to impede infection and maintain homeostatic regulation of the gut microbiota.	Hydrogen Peroxide	14-31	Dual oxidase	Drosophila melanogaster	60-64	
23394834-7	2013	We suggest that the wound-induced calcium flash activates DUOX via an EF hand calcium-binding motif and thus triggers the production of the attractant damage cue H2O2.	Hydrogen Peroxide	162-166	Dual oxidase	Drosophila melanogaster	58-62	
22242003-10	2011	One gene required to activate epidermal wound reporters encodes Dual oxidase, an enzyme that produces hydrogen peroxide.	Hydrogen Peroxide	102-119	Dual oxidase	Drosophila melanogaster	64-76	
34622778-5	2021	High ROS is dependent on expression of Duox, an H2O2 generating-Dual Oxidase.	Hydrogen Peroxide	48-52	Dual oxidase	Drosophila melanogaster	39-43	
34622778-7	2021	Tracheae deficient in Duox, or deficient in both Duox and regulators of DNA damage-dependent ATR/Chk1 activation (ATRIP/TOPBP1/ Claspin), can induce phosphorylation of Chk1 in response to micromolar concentrations of H2O2 in minutes.	Hydrogen Peroxide	217-221	Dual oxidase	Drosophila melanogaster	22-26	
34622778-7	2021	Tracheae deficient in Duox, or deficient in both Duox and regulators of DNA damage-dependent ATR/Chk1 activation (ATRIP/TOPBP1/ Claspin), can induce phosphorylation of Chk1 in response to micromolar concentrations of H2O2 in minutes.	Hydrogen Peroxide	217-221	Dual oxidase	Drosophila melanogaster	49-53